Patents by Inventor HyeonGyu SEO

HyeonGyu SEO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GPCR HETEROMER INHIBITORS AND USES THEREOF
    Publication number: 20220273751
    Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to ADRB2 that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and ADRB2 agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for pharmaceutical compositions and kits comprising a CXCR4 inhibitor and an ADRB2 inhibitor, and methods for treating and using the same, and in the diagnosis and/or therapy for cancer.
    Type: Application
    Filed: May 14, 2020
    Publication date: September 1, 2022
    Applicant: GPCR THERAPEUTICS, INC.
    Inventors: DongSeung SEEN, Eunhee KIM, SoHui KIM, HyeonGyu SEO, Jiyeong LEE, Chang Soo YANG, DongJin LEE, Jiwon YANG