Abstract: The present invention relates to a novel chimeric antigen receptor comprising a CD99 region which participates in immune synapse stabilization as a backbone of the chimeric antigen receptor, an immune cell comprising the same, and the uses thereof. CD99-based CAR-T cells are capable of forming very stable immune synapses with tumor cells compared to conventional backbone-based CAR-T cells and can exhibit improved tumor therapeutic efficiency, so they can be useful for immune cell therapy for the treatment of cancer.

Abstract: A hybrid catalyst composition containing a heterogeneous transition metal compound, a catalyst for olefin polymerization containing the heterogeneous transition metal compound, and a method for preparing an olefin-based polymer in which generation of a gel is suppressed using the catalyst are disclosed. The method for preparing an olefin-based polymer can provide an olefin-based polymer in which non-uniformity of the olefin-based polymer, and in particular, generation of a gel is suppressed.

Abstract: The present invention relates to an olefin-based polymer, and a method for preparing the same. The olefin-based polymer according to an embodiment of the present invention has a wide molecular weight distribution and thus has excellent processability. Moreover, a relatively large number of short-chain branches are present in high molecular weight components of the olefin-based polymer, and thus the olefin-based polymer has excellent mechanical strength and heat-sealing properties.

Abstract: An olefin-based polymer and a method for preparing the olefin-based polymer are disclosed. The olefin-based polymer has excellent heat-sealing property due to the high proportion of a copolymer, which has many branches and is derived from comonomers. The olefin-based polymer has a density of 0.915 to 0.950 g/cm3, a melt index (I2.16) of 0.5 to 1.5 g/10 min as measured with a load of 2.16 kg at 190° C., and a polydispersity index (Mw/Mn) of 2 to 6.

Abstract: The present invention relates to an olefin-based polymer, a film prepared therefrom, and preparation methods therefor. An olefin-based polymer according to an embodiment of the present invention has excellent processability, and a film prepared therefrom, particularly, a linear low density polyethylene film has excellent mechanical strength and heat sealability, in particular, low-temperature heat sealability.

Abstract: The present invention relates to an olefin-based polymer, a film prepared therefrom, and preparation methods therefor. An olefin-based polymer according to an embodiment of the present invention has excellent processability, and a film prepared therefrom, particularly, a linear low density polyethylene film has excellent mechanical strength, in particular, drop impact strength.

Abstract: The present invention relates to an olefin-based polymer and a method for preparing same. Specifically, the present invention relates to an olefin-based polymer for which processability can be controlled according to a change in density, and a method for preparing same. Processability of the olefin-based polymer according to an embodiment of the present invention can be controlled according to a change in density.

Abstract: The present invention relates to a process for preparing a hybrid catalyst for olefin polymerization, to a hybrid catalyst for olefin polymerization, and to a polyolefin. The supported hybrid metallocene catalyst for olefin polymerization prepared by the process for preparing a supported hybrid metallocene catalyst for olefin polymerization according to an embodiment of the present invention is capable of preparing a polyolefin having a broad molecular weight distribution of bimodal characteristics and being excellent in mechanical strength and processability.

Abstract: A catalyst containing mixed transition metal compounds is disclosed. The catalyst is capable of producing various polyolefins having excellent processability and mechanical properties. A polyolefin prepared using the catalyst and processes for preparing the polyolefin are disclosed. In the preparation process, it is possible to conveniently prepare a catalyst for olefin polymerization including mixed transition metal compounds by readily adjusting the ratio of the transition metal compounds.

Abstract: The present invention relates to a polyolefin film and to a process for preparing the same. The polyolefin film, specifically, the linear low-density polyethylene film according to an embodiment of the present invention is readily formed and has excellent mechanical strength and excellent heat seal characteristics.

Abstract: A display device in one example includes a display panel, a supporting frame supporting the display panel, and an adhesive between the display panel and the supporting frame. The supporting frame includes a case, and a thermal shape changing part constituting a portion of the case. The thermal shape changing part includes a shape memory material.

Abstract: An embodiment pertains to a method for evaluating efficacy of a drug which increases or decreases the secretion of a particular neurotransmitter, by measuring a concentration change of the particular neurotransmitter in a specific intracerebral site with reference to a brain map, the method comprising the steps of: selecting as a microdialysis target region in the brain map a first site of an animal, which corresponds to a site that the brain map represents as being the highest in the concentration of a first neurotransmitter of which the secretion is increased or decreased by the drug; and injecting the drug to the animal and monitoring a concentration change of the first neurotransmitter in the first site between pre- and post-injection of the drug.

Abstract: The present invention relates to a process for preparing a catalyst for olefin polymerization. Specifically, the present invention relates to a process for preparing a supported metallocene catalyst capable of enhancing the operational stability during olefin polymerization by treating the supported metallocene catalyst with an antistatic agent. In the process for preparing a supported metallocene catalyst according to the embodiment of the present invention, it is possible to enhance the operational stability during olefin polymerization by treating the supported metallocene catalyst with an antistatic agent in an improved method.

Abstract: The present invention relates to a process for preparing a catalyst for olefin polymerization. Specifically, the present invention relates to a process for preparing a supported metallocene catalyst capable of producing a polyolefin in which the formation of gels is suppressed. In the process for preparing a supported metallocene catalyst according to an embodiment of the present invention, it is treated with a metallic stearate after a transition metal compound has been supported, which suppresses the formation of a macromolecular polyolefin. Thus, a polyolefin with minimal gel formation can be prepared.

Abstract: The present invention relates to a method for screening a pain-inhibiting substance, said method comprising the steps of: (a) inserting a microdialysis probe into the L1 site of a spinal cord dorsal horn of a neuropathic pain animal model; (b) collecting a first test sample from the L1 site by microdialysis; (c) administering a pain-inhibiting candidate substance into the body of the animal model; (d) after having administered the pain inhibiting candidate substance, then collecting a second test sample from the L1 site by microdialysis; (e) measuring the concentrations of a pain indicator substance in the first test sample and second test sample respectively; and (f) comparing the concentrations of the pain indicator substance in the first test sample and second test sample.

Abstract: Provided are an ethylene-based polymer having excellent long-term pressure resistance characteristics and a pipe using the ethylene-based polymer. The ethylene-based polymer satisfies the balance of mechanical characteristics and excellent molding processability, as compared with a conventional ethylene-based polymer. Also provided are an ethylene-based polymer having a wide molecular weight distribution and a small lamellar thickness, thereby increasing tie molecules and obtaining excellent long-term pressure resistance characteristics, and a pipe using the same.

Abstract: The present invention relates to a novel Group 4 transition metal compound, a method for preparing the compound, a catalyst composition comprising the compound, and a method for preparing a polyolefin comprising performing a polymerization reaction of olefin monomers, in the presence of the catalyst composition. Since the Group 4 transition metal compound of the present invention exhibits an excellent catalytic activity in polyolefin synthesis reactions, as well as having excellent thermal stability, it can be used for polyolefin synthesis reactions at high temperatures, and by changing the type of a central metal and ligand, the weight average molecular weight of synthesized polyolefins and the octene content in the polymer can be controlled. Therefore, it can be effectively used in polyolefin synthesis processes in which grades are controlled.

Abstract: The present invention relates to a novel Group 4 transition metal compound, a method for preparing the compound, a catalyst composition comprising the compound, and a method for preparing a polyolefin comprising performing a polymerization reaction of olefin monomers, in the presence of the catalyst composition. Since the Group 4 transition metal compound of the present invention exhibits an excellent catalytic activity in polyolefin synthesis reactions, as well as having excellent thermal stability, it can be used for polyolefin synthesis reactions at high temperatures, and by changing the type of a central metal and ligand, the weight average molecular weight of synthesized polyolefins and the octene content in the polymer can be controlled. Therefore, it can be effectively used in polyolefin synthesis processes in which grades are controlled.

Abstract: The present invention relates to a novel group 4 transition metal compound, a method for preparing the compound, a catalyst composition containing the compound, and a method for preparing a polyolefin, comprising a step for forming a polymerization reaction of olefin monomers in the presence of the catalyst composition. The group 4 transition metal compound of the present invention exhibits an excellent catalytic activity and has excellent thermal stability in a polyolefin synthesis reaction, and thus can be used even in a polyolefin synthesis reaction at a high temperature. In addition, the compound of the present invention can be advantageously used in the synthesis process of grade-controlled polyolefin since the weight average molecular weight of the synthesized polyolefin and the octane content in the polymer can be adjusted by varying the kinds of center metal and ligand.

Abstract: A display device in one example includes a display panel, a supporting frame supporting the display panel, and an adhesive between the display panel and the supporting frame. The supporting frame includes a case, and a thermal shape changing part constituting a portion of the case. The thermal shape changing part includes a shape memory material.