Abstract: A method for fabrication of microparticles using a photo-polymerizable colloidal dispersant is provided. The method includes (a) preparing liquid droplets in a continuous phase from photo-polymerizable resin containing colloidal particles dispersed therein, then, allowing the colloidal particles to move toward an interface of the liquid droplets; and (b) UV exposing the liquid droplets to enable photo-polymerization thereof, so as to produce microparticles having a structure formed of colloidal particles on a surface of the microparticles. In addition, in order to improve the surface structure and characteristics, the foregoing method further includes (c) selective chemical reaction of the colloidal particles formed on the surface of the microparticles or, otherwise, removal of the colloidal particles.