Patents by Inventor Hyeshik CHANG

Hyeshik CHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for analyzing 3? end sequence of messenger RNA
    Patent number: 10633696
    Abstract: The present disclosure provides a new protocol for sequencing the 3? end of messenger RNA (mRNA). The present disclosure can be very favorably used in analyzing the repetitive sequences of nucleic acids, which are difficult to analyze by current sequencing methods, especially, homopolymeric sequences (poly[A] sequence) of mRNA. The present disclosure has significantly improved sensitivity to mRNA compared with an existing method, thereby obtaining a lot of genetic information from a small amount of sample. The method of the present disclosure reduces the time and cost for sequencing the 3? end of mRNA and can be applied to various samples, and thus, can be used as a useful tool in the study of RNA synthesis/degradation and protein production in association with all life phenomena, including embryogenesis, cancer, and neurotransmission.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: April 28, 2020
    Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: V. Narry Kim, Jaechul Lim, Hyeshik Chang
  • METHOD FOR ANALYZING 3' END SEQUENCE OF MESSENGER RNA
    Publication number: 20180119213
    Abstract: The present disclosure provides a new protocol for sequencing the 3? end of messenger RNA (mRNA). The present disclosure can be very favorably used in analyzing the repetitive sequences of nucleic acids, which are difficult to analyze by current sequencing methods, especially, homopolymeric sequences (poly[A] sequence) of mRNA. The present disclosure has significantly improved sensitivity to mRNA compared with an existing method, thereby obtaining a lot of genetic information from a small amount of sample. The method of the present disclosure reduces the time and cost for sequencing the 3? end of mRNA and can be applied to various samples, and thus, can be used as a useful tool in the study of RNA synthesis/degradation and protein production in association with all life phenomena, including embryogenesis, cancer, and neurotransmission.
    Type: Application
    Filed: July 21, 2017
    Publication date: May 3, 2018
    Applicants: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCE
    Inventors: V. Narry KIM, Jaechul LIM, Hyeshik CHANG