Abstract: A method for preparing an aliphatic isocyanate according to an exemplary embodiment of the present disclosure includes a first step of introducing an aliphatic amine and an organic solvent into a reactor, a second step of supplying gaseous hydrogen chloride into the reactor through a sparger, and a third step of stirring the aliphatic amine and the organic solvent, and the hydrogen chloride with a stirrer installed in the reactor, wherein in the third step, a stirring force of the stirrer is controlled to 500 to 4,000 W/m3.

Abstract: Provided are a compound capable of degrading a target protein using ubiquitin and having a targeted protein binding moiety (TBM) structure binding to a target protein or polypeptide and a ubiquitin binding moiety (UBM) structure to which ubiquitin is bound, wherein the compound can be induced to polyubiquitination by the UBM structure present in the compound, and thus have an advantage of becoming a protein degrader capable of degrading a target protein or polypeptide.

Abstract: The present disclosure provides a method for surface modification of a titanium implant material and a titanium implant obtained by the method for surface treatments. A titanium implant according to one embodiment of the present disclosure has high bond strength between implant and bone and its corrosion resistance.

Abstract: A drug administration management system according to an embodiment of the present disclosure may include a smart case configured to accommodate a drug administration device, display drug administration information including whether or not a drug is administered and a drug administration dose for each drug administration site input button based on an input of a user, and transmit the drug administration information externally; and a terminal configured to receive the externally transmitted drug administration information from the smart case, and monitor the drug administration information based on a drug administration plan input from a user.

Abstract: The present invention relates to fatty acid-modified polymer nanoparticles, and a use thereof. In the present invention, nanoparticles having embedded calcium carbonate crystals can be formed using a biocompatible polymer and an adipocyte-targeting ligand (a fatty acid) to minimize delivery to surrounding cells and tissues other than adipocytes and maximize the embedding of the nanoparticles into adipocytes. The nanoparticles according to the present invention can be produced as an injectable preparation, and can be applied to local lipolysis supplements or diet and beauty products that break down localized fat.

Abstract: A batch reactor according to an embodiment of the present disclosure includes: a reactor receiving a solvent in a liquid phase; a sparger configured to supply a raw material in a gas phase into the reactor; and a stirrer having an impeller on a rotational shaft installed in the reactor in a height direction to stir the solvent and the raw material, in which the impeller includes a radial-type impeller and an axial-type impeller.

Abstract: Disclosed are a vector comprising a first expression cassette comprising a DmpR ribosomal binding site as a transcriptional regulator and a promoter operably linked thereto; and a second expression cassette comprising a sequence encoding a target polypeptide, a ribosomal binding site, and a Po promoter operably linked thereto, and a methanotroph transformed by the vector.

Abstract: The present invention pertains to: a batch-type suspension polymerization stirrer for producing polyvinyl chloride; and a batch-type suspension polymerization reactor using same. More specifically, the present invention pertains to a batch-type exothermic reactor for performing vinyl chloride polymerization while controlling the internal temperature of an exothermic reaction chamber. Even more specifically, the present invention pertains to an invention wherein the structure of a reflux condenser among jacket, baffle, and reflux condenser devices responsible for heat removal in a reactor is designed to improve productivity and polymerization efficiency.

Abstract: A method for forming a photoresist relief image including applying a layer of a coating composition on a substrate; and disposing a layer of a photoresist composition on the layer of the coating composition, wherein the coating composition comprises an amine-containing polymer comprising a hydrocarbon-substituted amino group and having nitrogen atoms in an amount from 3 to 47 weight percent, based on a total weight of the amine-containing polymer.

Abstract: An anti-reflective coating composition is provided. The anti-reflective coating composition of the present invention can be useful in preventing a pull-back phenomenon in which an anti-reflective coating layer tears on a corner of a pattern of a substrate during a heat curing process and improving gap-filling performance of the pattern since a crosslinker is attached to a polymer in the composition and the content of the low-molecular-weight crosslinker in the composition is minimized to regulate a heat curing initiation temperature.

Abstract: Organic coating compositions, particularly antireflective coating compositions for use with an overcoated photoresist, are provided that comprise that a blend of two or more resins, where one resin has epoxy groups either pendant or fused to the polymer backbone. Preferred coating compositions include: 1) a first resin that comprises one or more epoxy reactive groups; and 2) a crosslinker resin that is distinct from the first resin and comprises epoxy groups.

Abstract: Provided is a hydrogenation method of a phthalate compound. According to the present invention, in the hydrogenation reaction, generation of by-products is suppressed, and thus catalytic activity is improved and life-time is extended, thereby increasing efficiency of a commercial process and economic efficiency. Further, since the hydrogenation product prepared by the present invention has high purity and a low acid value, its quality as a plasticizer is excellent, thereby being applied to a variety of products.

Abstract: Provided is a hydrogenation method of a phthalate compound. According to the present invention, in the hydrogenation reaction, generation of by-products is suppressed, and thus catalytic activity is improved and life-time is extended, thereby increasing efficiency of a commercial process and economic efficiency. Further, since the hydrogenation product prepared by the present invention has high purity and a low acid value, its quality as a plasticizer is excellent, thereby being applied to a variety of products.

Abstract: Provided is a hydrogenation method of a phthalate compound. According to the present invention, stereoselectivity of the hydrogenation reaction may be increased, and thus the content of a cis isomer in a product may be increased. As a result, quality of the hydrogenation product as a plasticizer may be improved.

Abstract: The present invention relates to a method for forming a pattern by negative tone development (NTD) which is prepared by forming an anti-reflective coating composition layer comprising a photoacid generator between the substrate and the photoresist composition layer, and thus exhibits improved line width (CD) in the pattern and prevents pattern collapse owing to thorough activation of de-blocking of the photoresist composition layer during the exposure process.

Abstract: The present invention relates to an efficient method and apparatus for remotely providing/downloading a profile for use in a communication service in a communication system, and the method for downloading the profile in the communication system, according to one embodiment of the present invention, comprises the steps of: transmitting, to a first server, first information for processing a request for downloading a profile; receiving, from the first server, address information of a second server processing the request for downloading the profile on the basis of the first information; transmitting, to the second server, second information for calling a function, of an application, related to the downloading of the profile; receiving, from the second server, the profile-related information as a response of the second information for calling the function; and connecting to a third server providing the profile on the basis of the profile-related information, and downloading the profile.

Abstract: A method for forming a photoresist relief image including applying a layer of a coating composition on a substrate; and disposing a layer of a photoresist composition on the layer of the coating composition, wherein the coating composition comprises an amine-containing polymer comprising a hydrocarbon-substituted amino group and having nitrogen atoms in an amount from 3 to 47 weight percent, based on a total weight of the amine-containing polymer.

Abstract: Disclosed are: a communication technique and a system therefor for fusing, with IoT technology, a 5G communication system for supporting a data transmission rate higher than that of a 4G system. Provided is a method for installing a profile of a terminal having an embed universal integrated circuit card (eUICC) in a mobile communication system, the method comprising: requesting for an eUICC authentication certificate to an eUICC and receiving the eUICC authentication certificate; and transferring a profile package to the eUICC so as to install a profile, wherein the received eUICC authentication certificate further comprises an eUICC manufacturer (EUM) authentication certificate.