Patents by Inventor Hyo-Eun Yoon

Hyo-Eun Yoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pheophorbide-? conjugates and their uses
    Patent number: 8940783
    Abstract: The present invention relates to a pheophorbide-? conjugate or its salt, solvate or hydrate. The pheophorbide-? conjugate of the present invention exhibiting fluorescence upon its introduction into cells and degradation inhibits the survival of various cancer cells. Especially, the conjugate of pheophorbide-? (1) and doxorubicin shows higher fluorescence intensity at lower pH (cancer environment). Therefore, the present composition for photodynamic therapy (PDT) of cancers is also very useful in detecting cancers. Interestingly, the anticancer effects of the present composition are dually exerted with help of both the photosensitizer and the anticancer drug of the present conjugates.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: January 27, 2015
    Assignee: Gwangju Institute of Science and Technology
    Inventors: Yong-Chul Kim, Hyo Jin Ko, Hyun You, Jung-Hoon Yoon, Hyo-Eun Yoon