Patents by Inventor Hyo-Ick HWANG

Hyo-Ick HWANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220144774
    Abstract: Provided are a novel process for preparing (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine or a salt thereof, which is an intermediate useful for the preparation of tofacitinib, an intermediate used in the process, i.e., isopropanol solvate of methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate dibenzoyl-L-tartrate, an intermediate, having excellent stability, useful for the preparation of tofacitinib, i.e., (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine acetate, and a process for preparing tofacitinib or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 3, 2020
    Publication date: May 12, 2022
    Applicant: YUHAN CORPORATION
    Inventors: Sang-Ho OH, Doo-Byung LEE, Kyoung-Chan KWON, Sang-Won KIM, Hyo-Ick HWANG, Kyeong-Sill LEE, Ik-Su JO, Ji-Hye CHOI, Sung-Hee CHO, Su-Young LEE