Patents by Inventor Hyo-Jeong Bang

Hyo-Jeong Bang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing entecavir and intermediate used therein
    Patent number: 8569491
    Abstract: Disclosed are a novel, high-yield method for preparing entecavir and intermediates used therein.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: October 29, 2013
    Assignee: Hanmi Science Co., Ltd
    Inventors: Jae Heon Lee, Gha Seung Park, Jin Hee Kim, Tae Jin Choi, Ji Eun Lee, Jung Hee Han, Hyo Jeong Bang, Sun Young Jung, Young Kil Chang, Gwan Sun Lee, Maeng Sup Kim
  • NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN
    Publication number: 20120202998
    Abstract: Disclosed are a novel, high-yield method for preparing entecavir and intermediates used therein.
    Type: Application
    Filed: September 15, 2010
    Publication date: August 9, 2012
    Applicant: HANMI HOLDINGS CO., LTD.
    Inventors: Jae Heon Lee, Gha Seung Park, Jin Hee Kim, Tae Jin Choi, Ji Eun Lee, Jung Hee Han, Hyo Jeong Bang, Sun Young Jung, Young Kil Chang, Gwan Sun Lee, Maeng Sup Kim
  • 1-?-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivatives and process for the preparation thereof
    Patent number: 7858761
    Abstract: 1-?-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) having the 3-hydroxy group protected with a biphenylcarbonyl group is a solid which can be easily purified by a simple procedure such as recrystallization, and therefore, it can be advantageously used as an intermediate in the preparation of gemcitabine in a large scale. Further, the 1-?-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) can be prepared with high stereoselectivity using the compound of formula (V) as an intermediate.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: December 28, 2010
    Assignee: Hanmi Pharm. Co., Ltd
    Inventors: Jaeheon Lee, Gha-Seung Park, Moonsub Lee, Han Kyong Kim, Hyo-Jeong Bang, Young-Kil Chang, Gwan Sun Lee
  • Method for the preparation of 2?-deoxy-2?,2?-difluorocytidine
    Patent number: 7799907
    Abstract: Provided is an improved method for stereoselectively preparing 2?-deoxy-2?,2?-difluorocytidine of formula (I), which includes reacting a 1-halo ribofuranose compound with a nucleobase of formula (IV) in a solvent to obtain a nucleo side of formula (II) with removal of a silyl halide ((alkyl)3SiX (X=halide)); and deprotecting the nucleoside of formula (II) to obtain 2?-deoxy-2?,2?-difluorocytidine of formula (I). 2?-Deoxy-2?,2?-difluorocytidine of formula (I) is effective for treating various cancers such as non-small cell lung (NSCLC), pancreatic, bladder, breast or ovarian cancers.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: September 21, 2010
    Assignee: Hanmi Pharm. Co., Ltd
    Inventors: Jaeheon Lee, Gha Seung Park, Moonsub Lee, Hyo-Jeong Bang, Jae Chul Lee, Cheol Kyong Kim, Chang-Ju Choi, Han Kyong Kim, Hoe Chul Lee, Young-Kil Chang, Gwan Sun Lee
  • METHOD OF PREPARING S-(-)-AMLODIPINE OR A SALT THEREOF AND AN INTERMEDIATE USED THEREIN
    Publication number: 20100099884
    Abstract: The present invention provides a novel method for preparing S-(?)-amlodipine having a high optical purity or a salt thereof and an intermediate used therein.
    Type: Application
    Filed: January 29, 2008
    Publication date: April 22, 2010
    Applicant: HANMI PHARM. CO., LTD
    Inventors: Sun Young JANG, Sungbum Kim, Sangmin Yun, Hyo Jeong Bang, Han Kyong Kim, Kwee Hyun Suh
  • Method for the Preparation of 2'-Deoxy-2',2'-Difluorocytidine
    Publication number: 20070249818
    Abstract: This invention relates to an improved method for stereoselectively preparing 2¢¥-deoxy-2¢¥,2¢¥-difluorocytidine of formula (I), which comprises the steps of reacting a 1-halo ribofuranose compound of formula (III) with a nucleobase of formula (IV) in a solvent to obtain a nucleoside of formula (II) with removing the silyl halide of formula (V) produced during the reaction; and deprotecting the nucleoside of formula (II) to obtain 2¢¥-deoxy-2¢¥,2¢¥-difluorocytidine of formula (I).
    Type: Application
    Filed: December 29, 2003
    Publication date: October 25, 2007
    Applicant: Hanmi Pharm. Co.,Ltd
    Inventors: Jaeheon Lee, Gha Seung Park, Moonsub Lee, Hyo-Jeong Bang, Jae Lee, Cheol Kim, Chang-Ju Choi, Han Kyong Kim, Hoe Chul Lee, Young-Kil Chang, Gwan Lee
  • 1-Alpha-Halo-2,2-Difluoro-2-Deoxy-D-Ribofuranose Derivatives and Process for the Preparation Thereof
    Publication number: 20070238865
    Abstract: 1-?-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) having the 3-hydroxy group protected with a biphenylcarbonyl group is a solid which can be easily purified by a simple procedure such as recrystallization, and therefore, it can be advantageously used as an intermediate in the preparation of gemcitabine in a large scale. Further, the 1-?-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) can be prepared with high stereoselectivity using the compound of formula (V) as an intermediate.
    Type: Application
    Filed: June 21, 2005
    Publication date: October 11, 2007
    Applicant: Hanmi Pharm Co., Ltd
    Inventors: Jaeheon Lee, Gha Park, Moonsub Lee, Han Kim, Hyo-Jeong Bang, Young-Kil Chang, Gwan Lee