Abstract: A time resolved spectroscopy system and method are provided using digital processing techniques of a low power, continuous wave signal generated by a continuous wave light source, such as a cw laser. Time elapse is determined by measuring the time shift of the signal modulation sequence using the cross correlation of a return signal with the reference signal. The high resolution time delay is introduced at the start of each modulation cycle and the high resolution measurement is constructed by interlacing a data set based on the delay information. The high resolution TRS or fluorescence measurement is achieved by correlation calculation of the measured data and the reference code and deconvolving the autocorrelation function of the reference code.

Abstract: An apparatus for interpolating pixels using correlated dual sample-hold processing for detecting and removing dark current occurring during the feed through period to thereby improve the resolution of a 3-panel type video camera includes first and second composite delay elements for selectively delaying respective ones of signals corresponding to R, G and B channels to permit selected delay of a pair of the signals by 1/2 pitch delays of 1/3 pitch delays during interlacing for interpolating pixels. A method for signal processing using selected pitch delay values is also disclosed.

Abstract: The present invention relates to a conjugated medicinal agent prepared by combining asialoglycoprotein with a medicine which acts specifically on the liver. The conjugated medicinal agent of the present invention has the following formula (1): P-(S)x-Gal-GA-R, wherein in the P-(S)x-moiety, P is a peptide residue of a human serum glycoprotein and S is a sugar residue of a human serum glycoprotein; Gal is galactose residue; GA is glutaraldehyde residue; x is an integer equal to or greater than 1; and R is a medicinal component selected from the group consisting of interferon, acyclovir sodium, ribavirin, vidarabine, zidovudine, suramin, anti-sense oligonucleotide, ribozyme, leucovorin calcium, sodium-meglumine diatrizoate, gadolinium-DTPA, glutathione (GSH), prostaglandins, .sup.99m Tc and .sup.131 I. The present invention also includes a process for preparing the conjugated medicinal agent of formula (I), a pharmaceutical composition containing the conjugated medicine and the use of the conjugated medicine.