Abstract: Mechanical thrombectomy devices adapted for removing an occluding blood clot in a patient, and methods of manufacturing and using mechanical thrombectomy devices. Such a mechanical thrombectomy device includes a bore defining an interior passage of an aspiration catheter, and microstructures extending radially into the interior passage. The microstructures are adapted to engage a clot drawn into the aspiration catheter.

Abstract: A device for measuring and monitoring heart rate, respiration rate, and oxygen saturation of a subject is disclosed, which includes a biometric sensor board having a photosensor adapted to measure reflectance of red and infrared lights off skin tissue, wherein the biometric sensor board adapted to control one or more light emitting diodes (LEDs), wherein brightness of the LEDs are automatically adjusted to account for skin tone, thereby generating photoplethysmographic data, a processor unit adapted to analyze data measured by the biometric sensor board, and a display adapted to display results of the processed data remotely.

Abstract: A tissue stretching system includes a motor, a first pillar, a second pillar, a force sensor, and an imaging device. The tissue stretching system may be provided as a 2D axial tissue stretcher that may monitor changes in mechanical properties over time. Tissues may be coated onto the first pillar and/or the second pillar. In a specific example, the first pillar and/or the second pillar may be a PDMS (Polydimethylsiloxane) structure configured to probe the mechanical properties in between a designed gap of the first pillar and the second pillar. The motor of the tissue stretching system includes a microcontroller. The motor of the tissue stretching system may have high resolution capabilities to provide the appropriate strain to the sample. The tissue stretching system then determines the actual amount of strain applied to the sample.

Abstract: A transceiver includes a transmitter up-converting a frequency of input data to transmit data of a first frequency, an orthogonal basis generator receiving the input data from the transmitter to generate an orthogonal basis; and a receiver receiving the orthogonal basis from the orthogonal basis generator and receiving the transmitted data for down-converting a frequency of the received data to a second frequency different from the first frequency. The orthogonal basis generator includes, a multiplier multiplying the input data by a Gaussian characteristic value obtained by extracting a Gaussian characteristic of the data to generate an out of band emission (OOBE) value, and a polynomial block generating the orthogonal basis by using the OOBE value as an input to an Itô-Hermite polynomial.

Abstract: A reception signal processing device for cancelling a self-interference signal generated by a transmission signal of a transceiver includes: a reception unit for receiving a reception signal including a self-interference signal; a moment generation unit for generating a moment of the reception signal; an orthogonal polynomial generation unit for generating an orthogonal polynomial by calculating orthogonal polynomial coefficients from the moment; and a digital interference cancelling unit for cancelling the self-interference signal included in the reception signal using the orthogonal polynomial.

Abstract: Electronic devices having one or more platinum-based electrodes and methods of producing the same. Such an electronic device includes a platinum-based electrode having a protective layer thereon that includes graphene in an amount effective to reduce platinum corrosion of the electrode.

Abstract: Disclosed are a user detection technique, and a method and apparatus for channel estimation in a wireless communication system supporting massive multiple-input multiple-output.

Abstract: Drainage devices have a self-clearing capability for reducing obstructions and a controllable flow restriction capability for controlling drainage flow, and microactuators for providing such capabilities. Such a microactuator includes a frame and an appendage anchored to the frame such that the frame supports the appendage, the frame at least partially surrounds the appendage, and the appendage is disposed in an opening or window defined by the frame. The appendage includes a platform and at least one beam that anchors the platform to the frame to enable the appendage to deflect out of a plane defined by the frame. The platform may include a ferromagnetic material that enables the appendage to deflect in response to an applied magnetic field.

Abstract: A device for measuring and monitoring heart rate, respiration rate, and oxygen saturation of a subject is disclosed, which includes a biometric sensor board having a photosensor adapted to measure reflectance of red and infrared lights off skin tissue, wherein the biometric sensor board adapted to control one or more light emitting diodes (LEDs), wherein brightness of the LEDs are automatically adjusted to account for skin tone, thereby generating photoplethysmographic data, a processor unit adapted to analyze data measured by the biometric sensor board, and a display adapted to display results of the processed data remotely.

Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain the drug, a temporary seal closing the at least one opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release the drug within the reservoir through the at least one opening of the housing.

Abstract: A self-cleaning cannula for placement in a patient, including an elongated tube portion having an inner surface and an oppositely disposed outer surface, a first end fluidically connectable to a fluid source outside the patient and a second, oppositely disposed end for fluidically communicating with the patient, and a plurality of magnetic nanoparticles operationally connected to at least a portion of the cannula. The metallic nanoparticles may be energized by an applied oscillating magnetic field to heat the cannula.

Abstract: The self-clearing system includes a microactuator, a catheter lumen, and an actuation device. The microactuator includes a polyimide structural layer and a conduction layer. The polyimide structural layer has a main body and a flexure. The conduction layer is coupled to the polyimide structural layer. The catheter lumen is configured to accept the microactuator. The actuation device is configured to wirelessly engage the microactuator.

Abstract: A self-cleaning cannula for placement in a patient, including an elongated tube portion having an inner surface and an oppositely disposed outer surface, a first end fluidically connectable to a fluid source outside the patient and a second, oppositely disposed end for fluidically communicating with the patient, and a plurality of magnetic nanoparticles operationally connected to at least a portion of the cannula. The metallic nanoparticles may be energized by an applied oscillating magnetic field to heat the cannula.

Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.

Abstract: A transceiver includes a transmitter up-converting a frequency of input data to transmit data of a first frequency, an orthogonal basis generator receiving the input data from the transmitter to generate an orthogonal basis; and a receiver receiving the orthogonal basis from the orthogonal basis generator and receiving the transmitted data for down-converting a frequency of the received data to a second frequency different from the first frequency. The orthogonal basis generator includes, a multiplier multiplying the input data by a Gaussian characteristic value obtained by extracting a Gaussian characteristic of the data to generate an out of band emission (OOBE) value, and a polynomial block generating the orthogonal basis by using the OOBE value as an input to an Itô-Hermite polynomial.

Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain a drug, a temporary seal closing the opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release a drug within the reservoir through the opening of the housing.

Abstract: Drainage devices and microactuator systems adapted to be incorporated into drainage devices to provide a self-clearing capability for reducing obstructions in the drainage devices and/or a self-monitoring capability to confirm the overall operating condition of the drainage devices and their microactuators. Such a microactuator system includes a microactuator having a base, a cantilever comprising a flexure extending from the base and a plate structure at a distal end of the flexure, a sensing element on the flexure for sensing deflection of the cantilever, and a device for inducing an oscillating deflection of the cantilever relative to the base.

Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain a drug, a temporary seal closing the opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release a drug within the reservoir through the opening of the housing.

Abstract: A direct electron transfer amperometric biosensor fabricated using direct write printing technology for in vivo electrochemical monitoring, such as monitoring of neurotransmitters and other biomarkers, e.g., in traumatic spinal cord injury. The biosensor is fabricated by immobilizing glutamate oxidase on nanocomposite electrodes made of platinum nanoparticles, multiwall carbon nanotubes and a conductive polymer on a flexible substrate.

Abstract: Electronic devices having one or more platinum-based electrodes and methods of producing the same. Such an electronic device includes a platinum-based electrode having a protective layer thereon that includes graphene in an amount effective to reduce platinum corrosion of the electrode.