Abstract: Methods, systems, and non-transitory computer-readable record media for managing event messages may be provided. A message management method may include generating, by at least one processor, an event related to a chatroom based on an event message input from the chatroom, assigning, by the at least one processor, a reply to the event message, from among messages in the chatroom, to the event, and displaying, by the at least one processor, the reply to the event message in association with the event.

Abstract: Methods, systems, and non-transitory computer-readable record media for managing event messages may be provided. A message management method may include generating, by at least one processor, an event related to a chatroom based on an event message input from the chatroom, assigning, by the at least one processor, a reply to the event message, from among messages in the chatroom, to the event, and displaying, by the at least one processor, the reply to the event message in association with the event.

Abstract: A method, a system, and a non-transitory computer readable record medium for providing a reminder message are provided. A reminder providing method may include recognizing a reminder request message among one or more messages exchanged through a chatroom; creating a reminder message based on the reminder request message; and sending the reminder message in the chatroom at a time preset for the reminder request message.

Abstract: Methods, systems, and non-transitory computer-readable record media for managing event messages may be provided. A message management method may include generating, by at least one processor, an event related to a chatroom based on an event message input from the chatroom, assigning, by the at least one processor, a reply to the event message, from among messages in the chatroom, to the event, and displaying, by the at least one processor, the reply to the event message in association with the event.

Abstract: A method and an apparatus for selecting a construction scenario for remodeling a building facade are disclosed. A method for selecting a construction scenario for remodeling a building facade, according to an embodiment of the present invention, comprises the steps of: calculating a heat transmission coefficient value for each of a plurality of construction scenarios for remodeling a building facade; classifying, into candidate construction scenarios, construction scenarios of which the heat transmission coefficient value is greater than or equal to a reference value, from among the plurality of construction scenarios; calculating an environmental impact assessment value and an economic evaluation value for each of the candidate construction scenarios; and selecting, as a recommended construction scenario, at least one construction scenario among the candidate construction scenarios according to the environmental impact assessment values and the economic evaluation values.

Abstract: A method, a system, and a non-transitory computer readable record medium for providing a reminder message are provided. A reminder providing method may include recognizing a reminder request message among one or more messages exchanged through a chatroom; creating a reminder message based on the reminder request message; and sending the reminder message in the chatroom at a time preset for the reminder request message.

Abstract: Methods, systems, and non-transitory computer-readable record media for managing event messages may be provided. A message management method may include generating, by at least one processor, an event related to a chatroom based on an event message input from the chatroom, assigning, by the at least one processor, a reply to the event message, from among messages in the chatroom, to the event, and displaying, by the at least one processor, the reply to the event message in association with the event.

Abstract: Provided are urea derivatives of Formula I: with histone deacetylase (HDAC) inhibitory activity, optical isomers thereof, pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising the same. The provided urea derivatives of Formula I are selective histone deacetylase (HDAC) inhibitors and are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, and neurodegeneration.

Abstract: The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.

Abstract: The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.

Abstract: The present invention relates to novel azaindole derivatives, and more particularly, to novel azaindole derivatives having histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof or solvates thereof, the use thereof for the preparation of pharmaceutical compositions, pharmaceutical compositions containing the same, a method of treating disease using the pharmaceutical compositions, and methods for preparing the novel azaindole derivatives. The novel azaindole derivatives according to the present invention are selective histone deacetylase (HDAC) inhibitors, and may be used as agents for treating malignant tumor diseases, inflammatory diseases, rheumatoid arthritis, and neurodegenerative diseases.

Abstract: The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.

Abstract: The present invention relates to a novel hydroxamate derivatives, more specifically, to novel hydroxamate derivatives having inhibitory activity against Histone Deacetylase (HDAC), isomers thereof, pharmaceutically acceptable salts thereof, hydrates or solvates thereof, use for preparing pharmaceutical compositions, pharmaceutical compositions comprising the same, treatment method using said composition, and a preparing method of novel hydroxamate derivatives. The novel selective hydroxamate derivatives having inhibitory activity against Histone Deacetylase (HDAC) compositions can be used for treatment of inflammatory disease, rheumatoid arthritis, or degenerative disease.