Patents by Inventor Hyon Soo Han
Hyon Soo Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Adsorbents for radioisotopes, preparation method thereof, and radioisotope generators using the same
Patent number: 8758714Abstract: Disclosed is a novel adsorbent for use in a 99Mo/99mTc generator, which is a medical diagnostic radioisotope generator, and in a 188W/188Re generator, which is a therapeutic radioisotope generator. The adsorbent composed of sulfated alumina or alumina-sulfated zirconia exhibits adsorption capacity superior to that of conventional adsorbents, and is stable and is thus loaded in a dry state in an adsorption column so that the radioisotope 99Mo or 188W can be adsorbed. Thus, it is possible to miniaturize the column, and such a miniaturized column is small, convenient to use, and highly efficient, and extracts a radioisotope satisfying the requirements for pharmaceuticals, and thus can be useful for radioisotope generators extracting 99mTc or 188Re.Type: GrantFiled: June 7, 2012Date of Patent: June 24, 2014Assignee: Korea Atomic Energy Research InstituteInventors: Jun Sig Lee, Hyon Soo Han, Ul Jae Park, Kwang Jae Son, Hyeon Young Shin, Soon Bog Hong, Kang Duk Jang, Jong Sub Lee -
Patent number: 8454912Abstract: Disclosed herein is an radioisotope adsorbent including a bifunctional organosilane compound, including an organosiloxane functional group and a phosphate group, bonded on the surface of silica which is a bone structure of the adsorbent, and a method of preparing the radioisotope adsorbent, and a strontium/yttrium generator using the radioisotope adsorbent. Since the radioisotope adsorbent has a high adsorption capacity for 90Y such as 95% extraction efficiency or more from ICi 90Sr/90Y by using a column packed with 0.4 g of the adsorbent with a high-purity of 90Y, it can be usefully to be employed in the fields requiring 90Y.Type: GrantFiled: March 27, 2009Date of Patent: June 4, 2013Assignee: Korea Atomic Energy Research InstituteInventors: Jun Sig Lee, Hyon-Soo Han, Ul-Jae Park, Kyung-Duk Jang, Hyeon-Young Shin, Soon-Bog Hong, Kwang-Jae Son
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Adsorbents for Radioisotopes, Preparation Method Thereof, and Radioisotope Generators Using the Same
Publication number: 20120244055Abstract: Disclosed is a novel adsorbent for use in a 99Mo/99mTc generator, which is a medical diagnostic radioisotope generator, and in a 188W/188Re generator, which is a therapeutic radioisotope generator. The adsorbent composed of sulfated alumina or alumina-sulfated zirconia exhibits adsorption capacity superior to that of conventional adsorbents, and is stable and is thus loaded in a dry state in an adsorption column so that the radioisotope 99Mo or 188W can be adsorbed. Thus, it is possible to miniaturize the column, and such a miniaturized column is small, convenient to use, and highly efficient, and extracts a radioisotope satisfying the requirements for pharmaceuticals, and thus can be useful for radioisotope generators extracting 99mTc or 188Re.Type: ApplicationFiled: June 7, 2012Publication date: September 27, 2012Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Jun Sig LEE, Hyon Soo HAN, Ul Jae PARK, Kwang Jae SON, Hyeon Young SHIN, Soon Bog HONG, Kang Duk JANG, Jong Sub LEE -
Publication number: 20110020206Abstract: Disclosed herein is an radioisotope adsorbent including a bifunctional organosilane compound, including an organosiloxane functional group and a phosphate group, bonded on the surface of silica which is a bone structure of the adsorbent, and a method of preparing the radioisotope adsorbent, and a strontium/yttrium generator using the radioisotope adsorbent. Since the radioisotope adsorbent has a high adsorption capacity for 90Y such as 95% extraction efficiency or more from ICi 90Sr/90Y by using a column packed with 0.4 g of the adsorbent with a high-purity of 90Y, it can be usefully to be employed in the fields requiring 90Y.Type: ApplicationFiled: March 27, 2009Publication date: January 27, 2011Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Jun Sig Lee, Hyon-Soo Han, Ui-Jae Park, Kyung-Duk Jang, Hyeon-Young Shin, Soon-Bog Hong, Kwang-Jae Son
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Adsorbents for Radioisotopes, Preparation Method Thereof, and Radioisotope Generators Using the Same
Publication number: 20100248955Abstract: Disclosed is a novel adsorbent for use in a 99Mo/99mTc generator, which is a medical diagnostic radioisotope generator, and in a 188W/188Re generator, which is a therapeutic radioisotope generator. The adsorbent composed of sulfated alumina or alumina-sulfated zirconia exhibits adsorption capacity superior to that of conventional adsorbents, and is stable and is thus loaded in a dry state in an adsorption column so that the radioisotope 99Mo or 188W can be adsorbed. Thus, it is possible to miniaturize the column, and such a miniaturized column is small, convenient to use, and highly efficient, and extracts a radioisotope satisfying the requirements for pharmaceuticals, and thus can be useful for radioisotope generators extracting 99mTc or 188Re.Type: ApplicationFiled: June 11, 2010Publication date: September 30, 2010Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Jun Sig LEE, Hyon Soo HAN, Ul Jae PARK, Kwang Jae SON, Hyeon Young SHIN, Soon Bog HONG, Kang Duk JANG, Jong Sub LEE -
Adsorbents for Radioisotopes, Preparation Method Thereof, and Radioisotope Generators Using the Same
Publication number: 20090277828Abstract: Disclosed is a novel adsorbent for use in a 99Mo/99mTc generator, which is a medical diagnostic radioisotope generator, and in a 188W/188Re generator, which is a therapeutic radioisotope generator. The adsorbent composed of sulfated alumina or alumina-sulfated zirconia exhibits adsorption capacity superior to that of conventional adsorbents, and is stable and is thus loaded in a dry state in an adsorption column so that the radioisotope 99Mo or 188W can be adsorbed. Thus, it is possible to miniaturize the column, and such a miniaturized column is small, convenient to use, and highly efficient, and extracts a radioisotope satisfying the requirements for pharmaceuticals, and thus can be useful for radioisotope generators extracting 99mTc or 188Re.Type: ApplicationFiled: May 8, 2008Publication date: November 12, 2009Applicant: KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Jun Sig LEE, Hyon Soo HAN, Ul Jae PARK, Kwang Jae SON, Hyeon Young SHIN, Soon Bog HONG, Kang Duk JANG, Jong Sub LEE -
Publication number: 20080300444Abstract: Disclosed is an ophthalmic applicator for the treatment of pterygium or or glaucoma using a radioisotope. It comprises a source volume for containing the radioisotope therein; a filter volume for controlling a radiation dose emitted from the radioisotope; and an encapsulation volume for encompassing the source volume and the filter volume, wherein the radioisotope is pure 32P or a combination of 32P and 103Pd. Ensuring the formation of more ideal dose distributions than do the conventional 90Sr ophthalmic applicators, as described hitherto, the ophthalmic applicator for the treatment of pterygium or glaucoma using 32P or a combination of 32P and 103Pd can promise both high therapeutic effects on pterygium or glaucoma and high safety effects on the eye lens. Further, 32P and 103Pd are easier to produce and treat than is 90Sr, thereby allowing the radiotherapy to be useful.Type: ApplicationFiled: May 23, 2008Publication date: December 4, 2008Applicants: SEOUL NATIONAL UNIVERSITY HOSPITAL, KOREA ATOMIC ENERGY RESEARCH INSTITUTEInventors: Sung-Joon Ye, IlHan Kim, Won Ryang Wee, Mee Kum Kim, Kwang Jae Son, Hyon Soo Han, Ul Jae Park, Hyeon Young Shin
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Patent number: 7266173Abstract: A method for distillation of sulfur for preparing radioactive phosphorous nuclide includes the steps of: charging powdered sulfur into a target tube designed to have an upper and a bottom neck; degassing the target tube to form a vacuum therein, followed by heating the upper neck to seal the target tube; irradiating neutrons into the sealed target tube to produce radioactive phosphorous nuclide; heating the distillation zone to distill the remaining unreacted sulfur; and cleaving the target tube at the bottom neck to separate the distillation and the cooling zone from each other, the separated zones containing the radioactive phosphorous nuclide and the unreacted sulfur, respectively, whereby the radioactive phosphorous nuclide of high purity can be prepared while the sulfur can be recovered at high efficiency.Type: GrantFiled: June 4, 2002Date of Patent: September 4, 2007Assignee: Korea Atomic Energy Research InstituteInventors: Hyon Soo Han, Ul Jae Park, Hyeon Young Shin, Kwon Mo Yoo
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Patent number: 6627908Abstract: A radiation source assembly and a connector press used in producing such assemblies. In the radiation source assembly, each of the cap connector and the female connector is provided with internal round threads on its pigtail fitting hole, thus engaging with the large-diameter coil of the pigtail at the internal round threads through a thread engagement prior to a compression process of the press. The assembly also allows a person to know whether both ends of the pigtail fully reach desired points within the two connectors, thus securing a precise compressing target portion during a compression process of the press. The inserted lengths of the pigtail relative to the two connectors are maximize accomplishing a desired linearity of the assembly. In the assembly, a target biasing spring is provided on the capsule lid and allows the disc targets within the source capsule to effectively maintain a desired condition as point sources regardless of the number of targets.Type: GrantFiled: June 26, 2000Date of Patent: September 30, 2003Assignee: Korea Atomic Energy Research InstituteInventors: Hyon Soo Han, Woon Kap Cho, Soon Buk Hong, Kyeong Deuk Jang, Ul Jae Park
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Publication number: 20030095915Abstract: A method for distillation of sulfur for preparing radioactive phosphorous nuclide includes the steps of: charging powdered sulfur into a target tube designed to have an upper and a bottom neck; degassing the target tube to form a vacuum therein, followed by heating the upper neck to seal the target tube; irradiating neutrons into the sealed target tube to produce radioactive phosphorous nuclide; heating the distillation zone to distill the remaining unreacted sulfur; and cleaving the target tube at the bottom neck to separate the distillation and the cooling zone from each other, the separated zones containing the radioactive phosphorous nuclide and the unreacted sulfur, respectively, whereby the radioactive phosphorous nuclide of high purity can be prepared while the sulfur can be recovered at high efficiency.Type: ApplicationFiled: June 4, 2002Publication date: May 22, 2003Inventors: Hyon Soo Han, Ul Jae Park, Hyeon Young Shin, Kwon Mo Yoo