Abstract: Disclosed is a method for manufacturing a monocrystalline semiconductor material of the nitride of a group 13 element, comprising a step of depositing at least one separation layer comprising an element M selected among Ge, Zr, Y, Si, Se, Sc, Mg, In, W, La, Ti, Ta and Hf, by epitaxial growth on a starting substrate; characterised in that an interface layer of formula MvAlxOyNz is deposited between the starting substrate and the separation layer, wherein: - the atomic indices x and z are greater than 0 and less than or equal to 1; and, - the atomic indices v and y are between 0 and 1; and - the sum y+z is greater than 0.9 and less than or equal to 1.5; and - the sum v+y is greater than or equal to 0.3 and less than or equal to 1.