Abstract: The present invention relates to a pharmaceutical composition comprising (S)-2-(((4?-trifluoromethylbiphenyl-4-yl)methyl)amino)propanamide methanesulfonate or a pharmaceutically acceptable salt thereof as an effective ingredient for prevention or treatment of stroke.

Abstract: Disclosed are a syringe capable of measuring an inner temperature of a patient body and a method of manufacturing the same. In the syringe, a different metal from that of a syringe needle is deposited on an inclined surface of a tip portion of the syringe needle to form a thermocouple junction with the metal of the syringe needle, whereby the region causing pain in a patient body can be diagnosed while allowing administration of medicine thereto, thereby enabling efficient treatment and significantly reducing potential harm due to drug abuse.

Abstract: A diagnostic probe includes a tube having a predetermined length; a deformable cylinder installed by being fitted into the tube such that both ends thereof are exposed to an outside; a guide needle formed in a hollow shape, having a predetermined length, and arranged to surround an outer circumference of the tube; a direction controller connected with an end of the tube, and positioning or vibrating the tube in a radial direction by receiving power from the outside; a vibration generator vibrating the cylinder in an axial direction by receiving power from the outside; and a handle unit connected with the other end of the tube, and connected with the direction controller and the vibration generator.

Abstract: The present invention relates to a probe and a device for detecting abnormality of an intervertebral disc. More particularly, the present invention relates to a probe and a device for detecting abnormality of an intervertebral disc that gives vibration stimulation to the inner part of the intervertebral disc and obtains an ultrasonic image in order to sense the abnormality of the intervertebral disc causing discogenic pains and inspects whether the intervertebral disc is abnormal by measuring impedance in the intervertebral disc. The present invention provides a probe for detecting abnormality of an intervertebral disc including: a shaft connector; a vibration generator connected to the shaft connector; and an inspector connected to the vibration generator, wherein the vibration generator vibrates the inspector by using a piezoelectric element and a device for detecting abnormality of an intervertebral disc.

Abstract: Disclosed are a syringe capable of measuring an inner temperature of a patient body and a method of manufacturing the same. In the syringe, a different metal from that of a syringe needle is deposited on an inclined surface of a tip portion of the syringe needle to form a thermocouple junction with the metal of the syringe needle, whereby the region causing pain in a patient body can be diagnosed while allowing administration of medicine thereto, thereby enabling efficient treatment and significantly reducing potential harm due to drug abuse.

Abstract: The present invention relates to a probe and a device for detecting abnormality of an intervertebral disc. More particularly, the present invention relates to a probe and a device for detecting abnormality of an intervertebral disc that gives vibration stimulation to the inner part of the intervertebral disc and obtains an ultrasonic image in order to sense the abnormality of the intervertebral disc causing discogenic pains and inspects whether the intervertebral disc is abnormal by measuring impedance in the intervertebral disc. The present invention provides a probe for detecting abnormality of an intervertebral disc including: a shaft connector; a vibration generator connected to the shaft connector; and an inspector connected to the vibration generator, wherein the vibration generator vibrates the inspector by using a piezoelectric element and a device for detecting abnormality of an intervertebral disc.

Abstract: New and useful neurostimulation systems are provided that include an implantable pulse generator dimensioned and configured for implantation in the skull of a patient. The implantable pulse generator has an electrode operatively associated with a distal end portion thereof and can be provided with adjustment means, such as an adjustable biasing member or spring arranged between the electrode to the distal end portion of the pulse generator. Also provided are systems involving networked neurostimulators that are configured and adapted to work jointly in accordance with prescribed treatment protocol to effect a desired recovery from brain injury. Such networked neurostimulation systems are particularly advantageous for effecting relatively large and/or relatively distant regions of the brain. Additionally, systems and methods for motor-evoked potential (MEP)-based neuromodulation are provided. Further, AC and/or DC stimulation can be utilized, depending on the precise implementation.

Abstract: An implantable cortical electrical stimulation device having wireless power control function comprises: an electrical stimulation device (100) which is arranged through a perforation part of cranial bone (1) and upper part of which is covered with scalp and thus electrical stimulation is transferred outside dura meter (2) to cerebral cortex (3); a head set (200) which is provided controllably with antenna (210) connecting wirelessly with the electrical stimulation device (100) outside scalp and applying power, and is fixed to a head; and a control element (300) which controls the electrical simulation device (310) through a power wire (211) connected to the antenna (210) of the head set (200).

Abstract: Disclosed is an auto examination system for intervertebral discs which injects a contrast material into a human intervertebral disc at a regular velocity through a needle and then measures internal pressure of the intervertebral disc from the outside, and uses data, obtained by synchronizing the measured pressure data and a captured image of the intervertebral disc, as diagnosis data, so as to more accurately identify a pain region of intervertebral discs of a patient based on a variation in the internal pressure of the intervertebral disc.

Abstract: An epidural cortical stimulation system includes a stimulation body and a connecting lead. The stimulation body has a core formed of a shape-memory material, insulation provided around the core, defining an outer surface of the stimulation body, and at least one electrode arranged on the outer surface of the stimulation body, adapted and configured to contact the dura of a patient. The connecting lead extends from a proximal end of the body, and is adapted and configured for electrical communication with a control unit for providing power to the body electrical cortical stimulation.

Abstract: A self-expandable epidural cortical electrode includes an electrically conductive expandable body and a connecting lead extending from the body. The body has an insulating layer on a first side and at least one region on a second side without an insulating layer. The connecting lead is adapted and configured for electrical communication with a control unit for providing power to the body electrical cortical stimulation.

Abstract: The subject invention is directed to new and useful neurostimulation systems that include an implantable pulse generator dimensioned and configured for implantation in the skull of a patient. The implantable pulse generator has an electrode operatively associated with a distal end portion thereof and can be provided with adjustment means, such as an adjustable biasing member or spring arranged between the electrode to the distal end portion of the pulse generator. The subject invention is also directed to systems involving networked neurostimulators that are configured and adapted to work jointly in accordance with prescribed treatment protocol to effect a desired recovery from brain injury. Such networked neurostimulation systems are particularly advantageous for effecting relatively large and/or relatively distant regions of the brain. The subject invention is further directed to systems and methods for motor-evoked potential (MEP)-based neuromodulation.