Abstract: Disclosed is a toothbrush using an up-and-down movement pattern, in which two brushes are attached in series to each of inner surfaces of parallel first and second heads having an obtusely bent shape to perform up-and-down brushing. The toothbrush enables simultaneous brushing of inner and outer portions and a cusp portion of a tooth and a cheek pouch and removal of a tongue coating. The toothbrush includes the first and second heads, brushes longitudinally attached to the first and second heads, holes perforated in opposite end positions of the first and second heads, a C-shaped loop pivotally rotatably fitted into the holes of the first and second heads, an elongated U-shaped guide fixed to both ends of the first head, a transfer member connected to the elongated U-shaped guide so as to reciprocate in a longitudinal direction of the first head, and a gripper extending downward from the transfer member.