Abstract: Disclosed are a biochip capable of detecting and analyzing multivalent bindings between target protein and binding mediator from monovalent bindings and a method for manufacturing the same. A biochip according to an embodiment comprises: a hydrogel functional layer on which a binding mediator is formed and of which physical properties are changed by a reaction between target protein to be introduced and the binding mediator; and a transducer configured to deliver a displacement signal corresponding to a change in the physical properties of the hydrogel functional layer to an analysis instrument, wherein the reaction is multivalent bindings between the target protein and the binding mediator, and de-swelling occurs in at least a portion of the hydrogel functional layer by the multivalent bindings.

Abstract: Disclosed are a biochip capable of detecting and analyzing multivalent bindings between target protein and binding mediator from monovalent bindings and a method for manufacturing the same. A biochip according to an embodiment comprises: a hydrogel functional layer on which a binding mediator is formed and of which physical properties are changed by a reaction between target protein to be introduced and the binding mediator; and a transducer configured to deliver a displacement signal corresponding to a change in the physical properties of the hydrogel functional layer to an analysis instrument, wherein the reaction is multivalent bindings between the target protein and the binding mediator, and de-swelling occurs in at least a portion of the hydrogel functional layer by the multivalent bindings.

Abstract: Disclosed are a biochip capable of detecting and analyzing multivalent bindings between target protein and binding mediator from monovalent bindings and a method for manufacturing the same. A biochip according to an embodiment comprises: a hydrogel functional layer on which a binding mediator is formed and of which physical properties are changed by a reaction between target protein to be introduced and the binding mediator; and a transducer configured to deliver a displacement signal corresponding to a change in the physical properties of the hydrogel functional layer to an analysis instrument, wherein the reaction is multivalent bindings between the target protein and the binding mediator, and de-swelling occurs in at least a portion of the hydrogel functional layer by the multivalent bindings.

Abstract: Apparatus and method for increasing optical transmission bandwidth in response to chaining, in cascade, one or more slave lasers onto a master laser. Each laser is configured for optical injection locking (OIL) and each slave laser is locked onto the master laser. The first and each subsequent slave laser are detuned to tailor frequency characteristics of apparatus output. The transmitter can be scaled up by cascading additional injection-locked lasers together. The invention supports multiple compatible modulation formats, such as amplitude modulation (AM), phase modulation (PM), and frequency modulation (FM), for tailoring the output to the application of interest, while any type of laser can be used for the master and slave lasers.

Abstract: In one aspect, the invention relates to a semiconductor laser. The laser includes a substrate and an elongate unitary laser structure disposed on the substrate. In turn, the elongate unitary laser structure includes a first laser section, a second laser section, and a plurality of shared layers. The first and second laser sections are capable of lasing independently of each other. The shared layers form both the first laser section and the second laser section. The first laser section is adapted for injection locking the second laser section.