Patents by Inventor Hyun Ae Bae

Hyun Ae Bae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944661
    Abstract: The present invention provides a pharmaceutical composition for prevention or treatment of a stress disease and depression, the pharmaceutical composition be safely useable without toxicity and side effects by using an extract of leaves of Vaccinium bracteatum Thunb., which is natural resource of Korea, so that the reduction of manufacturing and production costs and the import substitution and export effects can be expected through the replacement of a raw material for preparation with a plant inhabiting in nature.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: April 2, 2024
    Assignee: JEONNAM BIOINDUSTRY FOUNDATION
    Inventors: Chul Yung Choi, Dool Ri Oh, Yu Jin Kim, Eun Jin Choi, Hyun Mi Lee, Dong Hyuck Bae, Kyo Nyeo Oh, Myung-A Jung, Ji Ae Hong, Kwang Su Kim, Hu Won Kang, Jae Yong Kim, Sang O Pan, Sung Yoon Park, Rack Seon Seong
  • Patent number: 10626426
    Abstract: The present invention relates to a microorganism of the genus Corynebacterium having an ability to produce L-arginine, and a method of producing L-arginine using the same.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: April 21, 2020
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyun Ae Bae, Han Hyoung Lee, Min Gyeong Kang, Jong Hyun Kim, Hye Won Kim
  • Patent number: 10273491
    Abstract: Provided are a novel promoter and a method of producing a target product using the same.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: April 30, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Seung Bin Lee, Hyun Ae Bae, Ji Hye Lee, Young Lyeol Yang
  • Patent number: 10266858
    Abstract: The present invention relates to a microorganism of the genus Corynebacterium, which has an enhanced activity of aspartate ammonia-lyase and/or aspartate aminotransferase, and thus has an enhanced ability to produce L-arginine, and to a method of producing L-arginine using the microorganism of the genus Corynebacterium.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: April 23, 2019
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyun Ae Bae, Min Gyeong Kang, Han Hyoung Lee, Hye Won Kim, Sung Gun Lee
  • Publication number: 20180066269
    Abstract: Provided are a novel promoter and a method of producing a target product using the same.
    Type: Application
    Filed: January 15, 2016
    Publication date: March 8, 2018
    Inventors: Seung Bin LEE, Hyun Ae BAE, Ji Hye LEE, Young Lyeol YANG
  • Publication number: 20170226545
    Abstract: The present invention relates to a microorganism of the genus Corynebacterium having an ability to produce L-arginine, and a method of producing L-arginine using the same.
    Type: Application
    Filed: October 13, 2015
    Publication date: August 10, 2017
    Inventors: Hyun Ae BAE, Han Hyoung LEE, Min Gyeong KANG, Jong Hyun KIM, Hye Won KIM
  • Patent number: 9689009
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: June 27, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook Chang, Jae Hyun Jo, Hyun Ae Bae, Byeong Cheol Song, Sol Kim, Hye Won Kim, Hye Won Um, Sung Hoo Jhon, Yong Uk Shin, Eun Bin Yang, Kyoung Min Lee, Soo An Shin
  • Publication number: 20170073715
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 16, 2017
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook CHANG, Jae Hyun JO, Hyun Ae BAE, Byeong Cheol SONG, Sol KIM, Hye Won KIM
  • Publication number: 20160145661
    Abstract: The present invention relates to a microorganism of the genus Corynebacterium, which has an enhanced activity of aspartate ammonia-lyase and/or aspartate aminotransferase, and thus has an enhanced ability to produce L-arginine, and to a method of producing L-arginine using the microorganism of the genus Corynebacterium.
    Type: Application
    Filed: April 23, 2014
    Publication date: May 26, 2016
    Inventors: Hyun Ae Bae, Min Gyeong Kang, Han Hyoung Lee, Hye Won Kim, Sung Gun Lee
  • Patent number: 9267161
    Abstract: The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: February 23, 2016
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyun Won Bae, Hyung Joon Kim, Jun Ok Moon, Jae Woo Jang, Jong Chul Kim, Tae Han Kim, Jin Suck Sung, Kyung Han Lee, Dae Cheol Kim, Hyo Jin Kim, Hyun Ae Bae, Sang Jo Lim
  • Publication number: 20140099680
    Abstract: The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
    Type: Application
    Filed: April 2, 2012
    Publication date: April 10, 2014
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Hyun Won Bae, Hyung Joon Kim, Jun Ok Moon, Jae Woo Jang, Jong Chul Kim, Tae Han Kim, Jin Suck Sung, Kyung Han Lee, Dae Cheol Kim, Hyo Jin Kim, Hyun Ae Bae, Sang Jo Lim
  • Patent number: 8623620
    Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: January 7, 2014
    Assignee: CJ Chieljedang Corporation
    Inventors: Jae Yeong Ju, Kwang Ho Lee, Hyun Ae Bae
  • Patent number: 8574874
    Abstract: The present invention relates to a transformed microorganism producing an L-amino acid using sucrose as a main carbon source, and a method for producing an L-amino acid using the same.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: November 5, 2013
    Assignee: CJ Cheiljedang Corporation
    Inventors: Jae Yeong Ju, Kwang Ho Lee, Hyun Ae Bae, Hyo Jin Kim, Keun Chul Lee, Young Bin Hwang, Kyu Soo Cho, Hye Min Park, Hyun Ah Kim
  • Patent number: 8557549
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: October 15, 2013
    Assignee: CJ Cheildjedang Corporation
    Inventors: Jin Sook Chang, Jae Hyun Jo, Hyun Ae Bae, Byeong Cheol Song, Sol Kim, Hye Won Kim
  • Patent number: 8426165
    Abstract: The present invention relates to a method for producing fermentation product from various carbon sources containing glycerol using Corynebacteria. More particularly, the present invention relates to a method for producing fermentation product from carbon sources containing glycerol or a part of glycerol with high yield and high productivity, by fermenting Corynebacteria introduced with the foreign gene glpDFK facilitating the use of glycerol and accumulating industrially useful amino acids in the culture medium.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: April 23, 2013
    Assignee: CJ Cheiljedang Corporation
    Inventors: Kwang-myung Cho, Kyung-oh Choi, Hyun-ae Bae
  • Publication number: 20120252078
    Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. with sucrose assimilability and L-amino acid producing ability is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to the sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability.
    Type: Application
    Filed: February 16, 2010
    Publication date: October 4, 2012
    Applicant: CJ Cheiljetdang Corporation
    Inventors: Jae Yeong Ju, Kwang Ho Lee, Hyun Ae Bae
  • Publication number: 20120190082
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
    Type: Application
    Filed: October 20, 2011
    Publication date: July 26, 2012
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook CHANG, Jae Hyun JO, Hyun Ae BAE, Byeong Cheol SONG, Sol KIM, Hye Won KIM
  • Publication number: 20120190081
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
    Type: Application
    Filed: October 20, 2011
    Publication date: July 26, 2012
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook CHANG, Jae Hyun JO, Hyun Ae BAE, Byeong Cheol SONG, Sol KIM, Hye Won KIM
  • Publication number: 20120190083
    Abstract: The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.
    Type: Application
    Filed: October 20, 2011
    Publication date: July 26, 2012
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Jin Sook CHANG, Jae Hyun JO, Hyun Ae BAE, Byeong Cheol SONG, Sol KIM, Hye Won KIM, Hye Won UM, Sung Hoo JHON, Yong Uk SHIN, Eun Bin YANG, Kyoung Min LEE, Soo An SHIN
  • Publication number: 20120122163
    Abstract: The present invention relates to a microorganism belonging to the genus Escherichia sp. and a method for producing L-amino acid using the same. The microorganism belonging to the genus Escherichia sp. has a sucrose assimilability and L-amino acid producing ability, which is obtained by introducing a gene encoding a sucrose assimilative microorganism-derived sucrose metabolic enzyme to sucrose non-assimilative microorganism belonging to the genus Escherichia sp. having an L-amino acid producing ability and sucrose PTS (phosphoenolpyruvate dependent sucrose phosphotransferase system) activity.
    Type: Application
    Filed: February 16, 2010
    Publication date: May 17, 2012
    Applicant: CJ Cheiljedang Corporation
    Inventors: Jae Yeong Ju, Kwang Ho Lee, Hyun Ae Bae