Abstract: A composition including one or more bacteria of the order Anaeroplasmatales for use as a medicament in methods of treatment or prevention of an inflammatory disorder of the digestive system. Preferred embodiments of the invention relate to methods employing Anaeroplasma in the treatment or prevention of an inflammatory disorder of the digestive system. Preferably, the inflammatory disorders of the digestive system are inflammatory bowel disease, colitis, Crohn's disease (CD) or ulcerative colitis (UC). Furthermore, it is preferable that the composition of the present invention causes increased TGF-? and/or IgA production in the intestine or other component of the digestive tract compared to subjects who have not received administration of the composition.

Abstract: A composition including one or more bacteria of the order Anaeroplasmatales for use as a medicament in methods of treatment or prevention of an inflammatory disorder of the digestive system. Preferred embodiments of the invention relate to methods employing Anaeroplasma in the treatment or prevention of an inflammatory disorder of the digestive system. Preferably, the inflammatory disorders of the digestive system are inflammatory bowel disease, colitis, Crohn's disease (CD) or ulcerative colitis (UC). Furthermore, it is preferable that the composition of the present invention causes increased TGF-? and/or IgA production in the intestine or other component of the digestive tract compared to subjects who have not received administration of the composition.

Abstract: The invention relates to a composition comprising an anchor region capable of binding to a plasma cell; and a binding region associated with the anchor region, wherein the binding region binds a specific plasma cell antibody.

Abstract: The invention relates to a composition comprising an anchor region capable of binding to a plasma cell; and a binding region associated with the anchor region, wherein the binding region binds a specific plasma cell antibody.

Abstract: The invention relates to a method for in-vitro detecting pathogenic T helper cells by incubating a sample of a body fluid or tissue taken from a mammal with substances specifically interacting with at least one gene product encoded by selected genes, which are differentially expressed compared to normal T helper cells, determining specific incubation products, correlating an amount of signal or change in signal with a concentration of the gene product in the sample, and detecting cell pathogenicity by comparing the concentration with another gene product concentration in a sample of non-pathogenic and/or pathogenic cells. Another object if the invention concerns a pharmaceutical composition for prophylaxis and therapy of chronicinflammatory. The invention also relates to a method for screening substances with the property to reduce the pathogenicity of T helper cells along with the symptoms of chronic inflammatory diseases.