Patents by Inventor Hyun Guy KANG
Hyun Guy KANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10801011Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.Type: GrantFiled: August 30, 2017Date of Patent: October 13, 2020Assignee: National Cancer CenterInventors: Byoung S. Kwon, Hyun-Guy Kang, Kwang-Hui Kim, Young-Woo Kim, Young-Ho Kim, Byung-Kiu Park, Sang-Yoon Park, Sang-Jae Park, Hyeon-Seok Eom, Ho-Sik Oh, Heon Yoo, Don-Gil Lee, Seung-Hoon Lee, Young-Joo Lee, Jin-Soo Lee, Beom-Kyu Choi
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Patent number: 10695039Abstract: The following description provides a biotissue sampling apparatus comprising a housing, a firing button configured on a rear-end of the housing; a tube with an aspirating hole configured to inject medicine in a tissue according to a longitudinal direction of a lower end and extended from a front-end of a housing; and a needle assembly that may move from the tube to a biopsy region by a button thereby cut a solid tissue and store or aspire a fluid tissue.Type: GrantFiled: November 29, 2013Date of Patent: June 30, 2020Assignee: NATIONAL CANCER CENTERInventors: Hyun Guy Kang, Kwang Gi Kim, Na Ri Yang, Sang Bong Lee
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Patent number: 10570371Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+ T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.Type: GrantFiled: March 26, 2018Date of Patent: February 25, 2020Assignee: Eutilex Co., Ltd.Inventors: Byoung S. Kwon, Hyun-Guy Kang, Kwang-Hui Kim, Young-Woo Kim, Young Ho Kim, Byung-Kiu Park, Sang-Yoon Park, Sang-Jae Park, Hyeon-Seok Eom, Ho-Sik Oh, Heon Yoo, Don-Gil Lee, Seung-Hoon Lee, Young-Joo Lee, Jin-Soo Lee, Beom-Kyu Choi
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Publication number: 20180216066Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+ T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.Type: ApplicationFiled: March 26, 2018Publication date: August 2, 2018Inventors: Byoung S. Kwon, Hyun-Guy Kang, Kwang-Hui Kim, Young-Woo Kim, Young Ho Kim, Byung-Kiu Park, Sang-Yoon Park, Sang-Jae Park, Hyeon-Seok Eom, Ho-Sik Oh, Heon Yoo, Don-Gil Lee, Seung-Hoon Lee, Young-Joo Lee, Jin-Soo Lee, Beom-Kyu Choi
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Publication number: 20180057793Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.Type: ApplicationFiled: August 30, 2017Publication date: March 1, 2018Inventors: Byoung Se Kwon, Hyun-Guy Kang, Kwang-Hui Kim, Young-Woo Kim, Young-Ho Kim, Byung-Kiu Park, Sang-Yoon Park, Sang-Jae Park, Hyeon-Seok Eom, Ho-Sik Oh, Heon Yoo, Don-Gil Lee, Seung-Hoon Lee, Young-Joo Lee, Jin-Soo Lee, Beom-Kyu Choi
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Publication number: 20150305721Abstract: The following description provides a biotissue sampling apparatus comprising a housing, a firing button configured on a rear-end of the housing; a tube with an aspirating hole configured to inject medicine in a tissue according to a longitudinal direction of a lower end and extended from a front-end of a housing; and a needle assembly that may move from the tube to a biopsy region by a button thereby cut a solid tissue and store or aspire a fluid tissue.Type: ApplicationFiled: November 29, 2013Publication date: October 29, 2015Inventors: Hyun Guy Kang, Kwang Gi Kim, Na Ri Yang, Sang Bong Lee
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Publication number: 20150259646Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.Type: ApplicationFiled: March 12, 2015Publication date: September 17, 2015Inventors: Byoung Se Kwon, Hyun-Guy Kang, Kwang-Hui Kim, Young-Woo Kim, Young-Ho Kim, Byung-Kiu Park, Sang-Yoon Park, Sang-Jae Park, Hyeon-Seok Eom, Ho-Sik Oh, Heon Yoo, Don-Gil Lee, Seung-Hoon Lee, Young-Joo Lee, Jin-Soo Lee, Beom-Kyu Choi
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Patent number: 9131970Abstract: A pin assembly for operation includes a hollow pin for operation having a plurality of side holes defined through an outer surface thereof and a head which is closed or open due to the presence of a through-hole; a hollow support having a pin fastening part formed therein in the shape of a groove to fasten one end of the pin for operation, and being open at both ends thereof, and a hollow injector for insertion into an insertion hole formed in the support, wherein the hollow pin for operation is fastened to the pin fastening part of the support, and by applying external force to one end of the support, the hollow pin for operation is inserted into a bone.Type: GrantFiled: June 11, 2013Date of Patent: September 15, 2015Assignee: National Cancer CenterInventor: Hyun Guy Kang
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Publication number: 20130345763Abstract: A pin assembly for operation includes a hollow pin for operation having a plurality of side holes defined through an outer surface thereof and a head which is closed or open due to the presence of a through-hole; a hollow support having a pin fastening part formed therein in the shape of a groove to fasten one end of the pin for operation, and being open at both ends thereof, and a hollow injector for insertion into an insertion hole formed in the support, wherein the hollow pin for operation is fastened to the pin fastening part of the support, and by applying external force to one end of the support, the hollow pin for operation is inserted into a bone.Type: ApplicationFiled: June 11, 2013Publication date: December 26, 2013Applicant: National Cancer CenterInventor: Hyun Guy Kang
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Publication number: 20100256692Abstract: Provided are a bone graft shaping system and method that are capable of precisely shaping a bone graft to compactly couple the bone graft to a bone area from which an affected part is removed during bone graft surgery.Type: ApplicationFiled: November 4, 2009Publication date: October 7, 2010Inventors: Hyun-Guy Kang, Kwang-Gi Kim
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Publication number: 20090318981Abstract: A pin assembly for operation includes a hollow pin for operation having a plurality of side holes defined through a wall thereof and a root part which is closed or open due to the presence of a through-hole; and a hollow support member having a pin fastening part formed therein in the shape of a groove to fasten one end of the pin for operation, and being open at both ends thereof, wherein the pin for operation is fastened to the pin fastening part of the support member, and by applying external force to one end of the support member, the pin for operation is inserted into a bone.Type: ApplicationFiled: August 13, 2008Publication date: December 24, 2009Applicant: NATIONAL CANCER CENTERInventor: Hyun Guy KANG