Patents by Inventor Hyun-Jung Choi
Hyun-Jung Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11628164Abstract: Salsolinol is a metabolite of alcohol and is cytotoxic, so that the salsolinol has been studied as a diagnostic biomarker for a liver disease and a liver cancer, but the salsolinol has not been reported as a therapeutic agent for the liver disease or the liver cancer. Since the salsolinol regulates tumor-related genes and inflammation-related genes specifically for men, it is experimentally found that the salsolinol has an effect of alleviating a liver cancer and an alcoholic hepatitis. Therefore, the salsolinol is contained together with a pharmaceutically acceptable salt as an effective ingredient and is provided as a pharmaceutical composition for treating the liver cancer or a health functional food for preventing and improving the alcoholic liver disease to have an effect of treating the liver disease and the liver cancer or preventing and improving the liver disease and the liver cancer.Type: GrantFiled: November 6, 2020Date of Patent: April 18, 2023Assignee: Sungshin Women's University R&DB FoundationInventors: Hye Kyung Na, Hong Kyung Yang, Hyun Jung Choi
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Publication number: 20220110930Abstract: Salsolinol is a metabolite of alcohol and is cytotoxic, so that the salsolinol has been studied as a diagnostic biomarker for a liver disease and a liver cancer, but the salsolinol has not been reported as a therapeutic agent for the liver disease or the liver cancer. Since the salsolinol regulates tumor-related genes and inflammation-related genes specifically for men, it is experimentally found that the salsolinol has an effect of alleviating a liver cancer and an alcoholic hepatitis. Therefore, the salsolinol is contained together with a pharmaceutically acceptable salt as an effective ingredient and is provided as a pharmaceutical composition for treating the liver cancer or a health functional food for preventing and improving the alcoholic liver disease to have an effect of treating the liver disease and the liver cancer or preventing and improving the liver disease and the liver cancer.Type: ApplicationFiled: November 6, 2020Publication date: April 14, 2022Inventors: Hye Kyung NA, Hong Kyung YANG, Hyun Jung CHOI
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ANTIAGING COMPOSITION COMPRISING CYTOCHALASIN D OR SAG, AND METHOD FOR SCREENING ANTIAGING SUBSTANCE
Publication number: 20200345694Abstract: The present disclosure relates to an antiaging composition containing cytochalasin D or SAG, and a method for screening an antiaging substance, and provides a new antiaging substance and a new method for discovering a new antiaging substance. Thus, it is possible to greatly contribute to the development of beauty industries and to meeting demands related with beauty and antiaging, if the present disclosure is effectively used.Type: ApplicationFiled: July 24, 2018Publication date: November 5, 2020Applicant: AMOREPACIFIC CORPORATIONInventors: Hyun Jung CHOI, Hyoung June KIM, Ji Yong JUNG, Tae Ryong LEE -
Patent number: 10344260Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.Type: GrantFiled: September 27, 2012Date of Patent: July 9, 2019Assignee: AMOREPACIFIC CORPORATIONInventors: Eun Gyung Cho, Bum Ho Bin, Tae Ryong Lee, Ji Yeon Han, Hyun Jung Choi
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Patent number: 10045926Abstract: The present invention relates to a composition containing a chemokine, particularly, an interferon-inducible T-cell alpha chemoattractant (ITACT) which can decrease the gene expression of a factor related to melanin pigment production in melanocytes, thereby exhibiting a skin whitening effect.Type: GrantFiled: July 24, 2015Date of Patent: August 14, 2018Assignee: Amorepacific CorporationInventors: Eun Kyung Lee, Ji Yeon Han, Eun Gyung Cho, Tae Ryong Lee, Hyun Jung Choi
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Patent number: 9867772Abstract: Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.Type: GrantFiled: October 3, 2014Date of Patent: January 16, 2018Assignee: AMOREPACIFIC CORPORATIONInventors: Eui Dong Son, Dae Jin Min, Hui Kyoung Chang, Hyun Jung Choi, Seong A Cho, Ji Hyun Kim, Tae Ryong Lee
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Publication number: 20180008530Abstract: Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.Type: ApplicationFiled: October 3, 2014Publication date: January 11, 2018Applicant: AMOREPACIFIC CORPORATIONInventors: Eui Dong SON, Dae Jin MIN, Hui Kyoung CHANG, Hyun Jung CHOI, Seong A CHO, Ji Hyun KIM, Tae Ryong LEE
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Publication number: 20170304175Abstract: The present disclosure discloses a novel use of genistein, epigallocatechin gallate (EGCG), derivatives thereof, isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof and solvates thereof. A composition containing genistein, epigallocatechin gallate, derivatives thereof isomers thereof, pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates thereof or solvates thereof reduces the expression of factors related to increase of melanin producing ability, reduces the expression of senescence marker proteins and regulates the expression of enzymes involved in melanin production, and thus may have an effect of rejuvenating cells including melanocytes.Type: ApplicationFiled: November 27, 2015Publication date: October 26, 2017Applicant: AMOREPACIFIC CORPORATIONInventors: Eun Kyung LEE, Myeong Jin GOH, Hyun Jung CHOI, Eun Gyung CHO, Tae Ryong LEE
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Publication number: 20170209358Abstract: The present invention relates to a composition containing a chemokine, particularly, an interferon-inducible T-cell alpha chemoattractant (ITACT) which can decrease the gene expression of a factor related to melanin pigment production in melanocytes, thereby exhibiting a skin whitening effect.Type: ApplicationFiled: July 24, 2015Publication date: July 27, 2017Applicant: Amorepacific CorporationInventors: Eun Kyung LEE, Ji Yeon HAN, Eun Gyung CHO, Tae Ryong LEE, Hyun Jung CHOI
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Patent number: 9417136Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.Type: GrantFiled: February 15, 2012Date of Patent: August 16, 2016Assignees: AMOREPACIFIC CORPORATION, SNU R&DB FOUNDATIONInventors: Eui Dong Son, Hyeon Chung Kim, Ji Hyun Kim, Hyun Jung Choi, Gae Won Nam, Tae Ryong Lee, Jin Ho Chung, Seon Pil Jin
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Patent number: 9303261Abstract: Disclosed is a composition for a whitening effect or for the prevention of gray hair, which includes antisense nucleic acid molecules of SEQ ID NO: 2, wherein the composition has an miRNA of SEQ ID NO: 1 or a base sequence complementary thereto. Also disclosed is a method for controlling chromogenesis in test materials and for screening for expression control materials of chromogenic genes. The composition and the screening methodcan be used for the whitening effect or for the prevention of gray hair.Type: GrantFiled: June 13, 2012Date of Patent: April 5, 2016Assignee: Amorepacific CorporationInventors: Kyu Han Kim, Hyun Jung Choi, Bum Ho Bin, Tae Ryong Lee
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Publication number: 20150044265Abstract: Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.Type: ApplicationFiled: October 3, 2014Publication date: February 12, 2015Applicant: AMOREPACIFIC CORPORATIONInventors: Eui Dong SON, Dae Jin MIN, Hui Kyoung CHANG, Hyun Jung CHOI, Seong A CHO, Ji Hyun KIM, Tae Ryong LEE
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Publication number: 20140227779Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.Type: ApplicationFiled: September 27, 2012Publication date: August 14, 2014Applicant: AMOREPACIFIC CORPORATIONInventors: Eun Gyung Cho, Bum Ho Bin, Tae Ryong Lee, Ji Yeon Han, Hyun Jung Choi
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Publication number: 20140134636Abstract: Disclosed is a composition for a whitening effect or for the prevention of gray hair, which includes antisense nucleic acid molecules of SEQ ID NO: 2, wherein the composition has an miRNA of SEQ ID NO: 1 or a base sequence complementary thereto. Also disclosed is a method for controlling chromogenesis in test materials and for screening for expression control materials of chromogenic genes. The composition and the screening method can be used for the whitening effect or for the prevention of gray hair.Type: ApplicationFiled: June 13, 2012Publication date: May 15, 2014Applicant: AMOREPACIFIC CORPORATIONInventors: Kyu Han Kim, Hyun Jung Choi, Bum Ho Bin, Tae Ryong Lee
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Publication number: 20130329766Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.Type: ApplicationFiled: February 15, 2012Publication date: December 12, 2013Applicants: SNU R&DB FOUNDATION, AMOREPACIFIC CORPORATIONInventors: Eui Dong Son, Hyeon Chung Kim, Ji Hyun Kim, Hyun Jung Choi, Gae Won Nam, Tae Ryong Lee, Jin Ho Chung, Seon Pil Jin
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Publication number: 20130303605Abstract: Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, as well as the use thereof for skin whitening.Type: ApplicationFiled: July 11, 2013Publication date: November 14, 2013Inventors: Hui Kyoung CHANG, Dae Gun KIM, Myeong Hoon YEOM, Hyun Jung CHOI, Kyung Mi JOO, Jae Sung HWANG, Soo Mi AHN
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Publication number: 20130171274Abstract: Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.Type: ApplicationFiled: August 30, 2011Publication date: July 4, 2013Applicant: AMOREPACIFIC CORPORATIONInventors: Eui Dong Son, Dae Jin Min, Hui Kyoung Chang, Hyun Jung Choi, Seong A. Cho, Ji Hyun Kim, Tae Ryong Lee
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Publication number: 20120301413Abstract: Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, as well as the use thereof for skin whitening.Type: ApplicationFiled: August 7, 2012Publication date: November 29, 2012Applicant: AMOREPACIFIC CORPORATIONInventors: Hui Kyoung CHANG, DaeGun KIM, Myeong Hoon YEOM, Hyun Jung CHOI, Kyung Mi JOO, Jae Sung HWANG, Soo Mi AHN
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Publication number: 20100256228Abstract: Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, ad well as the use thereof for skin whitening.Type: ApplicationFiled: November 2, 2007Publication date: October 7, 2010Applicant: Amorepacific CorporationInventors: Hui Kyoung Chang, Dae Gun Kim, Myeong Hoon Yeom, Hyun Jung Choi, Kyung Mi Joo, Jae Sung Hwang, Soo Mi Ahn
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Patent number: 7517911Abstract: The present invention relates to ester compounds derived from 3,4,5-trimethoxy phenyl acetate, 3,4,5-trimethoxy cinnamate or 3,4,5-trimethoxy hydrocinnamate that are represented by Formula (I), wherein R1 is CH2—, —CH?CH— or CH2—CH2, R2 is thymyl or carvacryl, to methods for preparing them, and to a whitening cosmetic composition containing the ester compounds. Because the ester compounds of the present invention inhibit the generation of melanin, the cosmetic composition can improve the skin pigmentation and can be used for whitening cosmetics.Type: GrantFiled: September 23, 2002Date of Patent: April 14, 2009Assignee: Amorepacific CorporationInventors: Ho-Sik Rho, Jae-Sung Hwang, Hyun-Jung Choi, Hyun-Jung Shin, Bae-Hwan Kim, Eun-Young Lee, Byeong-Gon Lee, Duck-Hee Kim