Patents by Inventor Hyun-Jung Chung

Hyun-Jung Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200140844
    Abstract: The present invention relates to a CRISPR nanocomplex for nonviral genome editing, a method for preparing the same, and the like. The CRISPR nanocomplex for nonviral genome editing of the present invention has a size of several nanometers to several microns, enables intracellular delivery without external physical stimulation, and can be utilized for genome editing through nonviral routes with respect to target genes of cells. As a result, when used for preparation of animal model, microbiological engineering, cell engineering for disease treatment, or formulations for biological administration, the CRISPR Nanocomplex shows high intracellular delivery and gene editing efficiency, and can minimize problems, such as nonspecific editing, gene mutation, and induction of cytotoxicity and biotoxicity.
    Type: Application
    Filed: November 27, 2017
    Publication date: May 7, 2020
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyun Jung CHUNG, Yoo Kyung KANG
  • Patent number: 10274490
    Abstract: The present invention provides novel methods of magnetically labeling a bacterial cell by contacting the call with an affinity ligand and subsequently contacting the cell with a magnetic agent, where the affinity ligand and magnetic agent include bioorthogonally reactive groups that can react with each other to form a covalent bond. Compounds, compositions, kits and applications of the method are also described.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: April 30, 2019
    Assignee: The General Hospital Corporation
    Inventors: Ghyslain Budin, Ralph Weissleder, Hakho Lee, Hyun Jung Chung
  • Publication number: 20150125884
    Abstract: The present invention provides novel methods of magnetically labeling a bacterial cell by contacting the call with an affinity ligand and subsequently contacting the cell with a magnetic agent, where the affinity ligand and magnetic agent include bioorthogonally reactive groups that can react with each other to form a covalent bond. Compounds, compositions, kits and applications of the method are also described.
    Type: Application
    Filed: March 8, 2013
    Publication date: May 7, 2015
    Inventors: Ghyslain Budin, Ralph Weissleder, Hakho Lee, Hyun Jung Chung
  • Patent number: 7112323
    Abstract: The present invention is directed bacterial isolates that produce proteinacious antimicrobial agents effective against a variety of food borne pathogens. The invention includes the bacteria, bacteriocin preparations derived from the bacteria and methods by which the preparations may be used.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: September 26, 2006
    Assignee: Kraft Foods Holdings, Inc.
    Inventors: Osama O. Ibrahim, Ahmed E. Yousef, Hyun-Jung Chung
  • Publication number: 20040223955
    Abstract: The present invention is directed bacterial isolates that produce proteinacious antimicrobial agents effective against a variety of food borne pathogens. The invention includes the bacteria, bacteriocin preparations derived from the bacteria and methods by which the preparations may be used.
    Type: Application
    Filed: May 7, 2003
    Publication date: November 11, 2004
    Applicant: KRAFT FOODS HOLDINGS, INC and OHIO STATE UNIVERSITY RESEARCH FOUNDATION,
    Inventors: Osama O. Ibrahim, Ahmed E. Yousef, Hyun-Jung Chung