Patents by Inventor Hyun Jung Junn

Hyun Jung Junn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High Throughput Screening Method of Binding Inhibitor Between caspase3 and XIAP and Binding Inhibitor Screened Thereby
    Publication number: 20090318376
    Abstract: The present invention relates to a high throughput screening method of a binding inhibitor between caspase3 and xIAP and chromomycin screened using the same, and more specifically, the present invention provides a method for screening anticancer substance, the method comprising the steps of reacting caspase3 or xIAP and candidate inhibitors of the binding between caspase3 and xIAP on a biochip for detecting caspase3:xIAP interaction, and selecting a candidate substance inhibiting the binding of caspase3 to xIAP as an anticancer substance, and an anticancer agent inhibiting caspase3:xIAP binding, which is screened by the above method. According to present invention, it is possible to develop a target-oriented anticancer agent focused on xIAP and caspase3, apoptosis-related proteins and thus it can be applied to tailored medication and combination therapy.
    Type: Application
    Filed: June 12, 2006
    Publication date: December 24, 2009
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Bong Hyun Chung, Kwang-Hee Son, Moonil Kim, Kyoungsook Park, Byoung-Mog Kwon, Hyun Jung Junn, Dong Cho Han, Sun-Hee Jeon