Patents by Inventor Hyun-Kee Kim

Hyun-Kee Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11970732
    Abstract: The present invention relates to a method for determining the DNA quality of a biological sample and, more specifically, to a method for determining the DNA quality of a biological sample by performing a quantitative polymerase chain reaction (PCR) using primers capable of amplifying a target gene, a method for preparing the primers used in the method, and a method for standardizing the amount of detected target gene mutation by using the determined DNA quality. The method of the present invention enables objective evaluation of the DNA quality of a biological sample used in gene analysis and the presentation of objective results on the expression ratio of a gene mutation, thereby providing reliable information in the fields of clinical research and companion diagnosis.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: April 30, 2024
    Assignees: GENCURIX INC., LOGONE BIO CONVERGENCE RESEARCH FOUNDATION
    Inventors: Young Kee Shin, Jin Ju Kim, Sung Su Kim, Hyun Jeung Choi, Young Ho Moon, Myung Sun Kim, Jee Eun Kim
  • Publication number: 20230312614
    Abstract: The present disclosure relates to a novel Group 4 metal element-containing compound having excellent thermal stability, a precursor composition including the compound, and a method for manufacturing a thin film using the precursor composition. The novel Group 4 metal element-containing compound according to the present disclosure and the vapor deposition precursor composition including the compound can have excellent thermal stability, realize thin film deposition in a wide temperature range, and reduce residues caused by heat loss, thereby preventing side reactions in a process. Additionally, the vapor deposition precursor composition according to the present disclosure can realize uniform thin film deposition, thereby securing excellent physical properties of the thin film.
    Type: Application
    Filed: September 6, 2021
    Publication date: October 5, 2023
    Inventors: Hyun-Kee KIM, Cheol-Wan PARK, Ki-Yeung MUN, Ee-Seul SHIN, Eun-Jeong CHO, Jang-Hyeon SEOK, Jung-Woo PARK
  • Patent number: 11382935
    Abstract: The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by A? (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: July 12, 2022
    Inventors: Sang Hee Kim, Hyun Kee Kim
  • Publication number: 20220105139
    Abstract: The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by A? (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 7, 2022
    Inventors: Sang Hee KIM, Hyun Kee KIM
  • Patent number: 11253553
    Abstract: The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by A? (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: February 22, 2022
    Inventors: Sang Hee Kim, Hyun Kee Kim
  • Publication number: 20220040240
    Abstract: The present invention relates to a composition for improving cognitive ability, and preventing or treating dementia and a hyperactivity disorder, which includes a Galla rhois extract and fraxin as active ingredients. It was identified that the composition including the Galla rhois extract and fraxin significantly improves cognitive memory in an Alzheimer's disease model induced by A? (1-42) administration and an APPswe/PS1dE9 double-expressing Alzheimer's disease model, and inhibits the generation of amyloid plaques, suggesting the usefulness of the combination of the Galla rhois extract and fraxin, as a therapeutic material, against Alzheimer's disease, and showing that the combination of the Galla rhois extract and fraxin is able to be used as a therapeutic agent for ADHD.
    Type: Application
    Filed: December 18, 2018
    Publication date: February 10, 2022
    Inventors: Sang Hee KIM, Hyun Kee KIM
  • Patent number: 9631011
    Abstract: The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 25, 2017
    Assignee: SNU R&DB FOUNDATION
    Inventors: Hyun Kee Kim, Junho Chung, Min Soo Kim, Soo Min Yoon
  • Publication number: 20150158938
    Abstract: The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.
    Type: Application
    Filed: March 15, 2013
    Publication date: June 11, 2015
    Inventors: Hyun Kee Kim, Junho Chung, Min Soo Kim, Soo Min Yoon
  • Publication number: 20120181175
    Abstract: The present invention relates to filler for analyzing capillary electrophoresis-based single strand conformation polymorphism, and to a method for using the filler for analyzing capillary electrophoresis-based single strand conformation polymorphism, and more particularly, to filler for analyzing capillary electrophoresis-based single strand conformation polymorphism, the filler containing a polymer micelle formed by dispersing a sandwich-block copolymer comprising (Hydrophilic group)-(Hydrophobic group)-(Hydrophilic group) in an aqueous medium, and to a method for using the filler for analyzing capillary electrophoresis-based single strand conformation polymorphism.
    Type: Application
    Filed: October 9, 2009
    Publication date: July 19, 2012
    Applicant: THE BIO CO., LTD
    Inventors: Hyun Kee Kim, Gyoo Yeol Jung, Gi Won Shin, Hee Sung Hwang
  • Publication number: 20100205681
    Abstract: A prognostic marker for breast cancer and a composition for inducing obesity are provided, wherein said marker and said composition comprise HCCR-1.
    Type: Application
    Filed: July 6, 2007
    Publication date: August 12, 2010
    Inventors: Hyun-Kee Kim, Jin-woo Kim
  • Publication number: 20090258878
    Abstract: The present invention relates to a Triazine derivative compound, pharmaceutically acceptable salt thereof and a pharmaceutical composition containing them. Compound or composition of the present invention is useful for cancer treatment, and especially has superior effect in breast cancer treatment.
    Type: Application
    Filed: July 6, 2007
    Publication date: October 15, 2009
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20090221794
    Abstract: Disclosed are a novel protooncogene and a protein encoded by the same. The protooncogene of the present invention may be effectively used for diagnosing various cancers including breast cancer, leukemia, uterine cancer, malignant lymphoma, etc.
    Type: Application
    Filed: March 30, 2006
    Publication date: September 3, 2009
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20090155896
    Abstract: Disclosed are a human cancer suppressor gene, a protein encoded therein, an expression vector containing the same, and a cell transformed by the vector. The gene of the present invention can be used for diagnosing, preventing and treating the human cancers.
    Type: Application
    Filed: December 22, 2005
    Publication date: June 18, 2009
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20090123918
    Abstract: Disclosed are a protooncogene and a protein encoded by the same. The protooncogene of the present invention, known to be involved in human carcinogenesis, may be effectively used for diagnosing various cancers including uterine cancer, leukemia, lymphoma, colon cancer, lung cancer, skin cancer, etc.
    Type: Application
    Filed: March 30, 2006
    Publication date: May 14, 2009
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20080293134
    Abstract: Disclosed are a human cancer suppressor gene, a proteins encoded therein, an expression vectors containing the same, and a microorganism transformed with the vector. The genes of the present invention may be useful to diagnose and prevent the human cancers.
    Type: Application
    Filed: December 28, 2005
    Publication date: November 27, 2008
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20080213764
    Abstract: Disclosed are a novel protooncogene and a protein encoded therein. The protooncogene of the present invention, which is a novel gene that takes part in human carcinogenesis and simultaneously has an ability to induce cancer metastasis, may be effectively used for diagnosing the cancers, including lung cancer, leukemia, uterine cancer, lymphoma, colon cancer, skin cancer, etc., as well as producing transformed animals, etc.
    Type: Application
    Filed: December 28, 2005
    Publication date: September 4, 2008
    Inventors: Hyun-Kee Kim, Jin-Woo Kim
  • Publication number: 20080213763
    Abstract: Disclosed are a novel protooncogene and a protein encoded by same. The protooncogene of the present invention is a novel gene, and may be effectively used for diagnosing the cancers, including leukemia, uterine cancer, lymphoma, colon cancer, lung cancer, skin cancer, etc., as well as producing transformed animals, etc.
    Type: Application
    Filed: December 28, 2005
    Publication date: September 4, 2008
    Inventors: Hyun-Kee Kim, Jin-Woo Kim