Patents by Inventor Hyun-Seung Ryu

Hyun-Seung Ryu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170354502
    Abstract: The present invention relates to a system for producing artificial osseous tissue comprising: a client computer acquiring an image information of a subject bone tissue from an imaging unit that picks up an image of a subject bone tissue of a patient to generate a 3D image information; a server computer identifying the subject bone tissue based on the image information of the subject bone tissue received from the client computer, generating a 3D image information of at least one therapeutic bone tissue model corresponding to the subject bone tissue, and transmitting the 3D image information of the at least one therapeutic bone tissue model to the client computer; and a machining unit for fabricating an artificial bone tissue based on the 3D image information of the therapeutic bone tissue model determined from the server computer.
    Type: Application
    Filed: December 24, 2015
    Publication date: December 14, 2017
    Inventor: Hyun Seung Ryu
  • Patent number: 9675731
    Abstract: The present invention relates to a bone graft composition and a preparation method thereof, and more particularly to a bone graft composition having excellent physical properties, which comprises a hydrogel comprising a combination of specific amounts of poloxamer and HPMC, and calcium phosphate compound particles, and a preparation method thereof.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: June 13, 2017
    Assignee: Bioalpha Corporation
    Inventors: Mi Young Ryu, Nam Yul Cho, Jun Hyuk Seo, Hyun Seung Ryu, So Myoung Lee
  • Publication number: 20170112969
    Abstract: The present invention relates to a carrier for growth factor related to regeneration of bone tissues that is capable of arbitrarily controlling the delivery rate of growth factors related to bone regeneration and thus especially applicable to a bone void filler in the fields of the dental or orthopedic applications. The carrier for controlling the delivery rate of the growth factor in the present invention is composed of a hyaluronic acid hydrogel having a distribution of interconnected pores and a calcium phosphate microsphere being distributed in the pores of the hyaluronic acid hydrogel. The calcium phosphate microsphere having a porosity suitable for delivery of the growth factor is positioned into the pores of the cross-linked hyaluronic acid hydrogel to complete the carrier.
    Type: Application
    Filed: January 9, 2017
    Publication date: April 27, 2017
    Inventors: JUNG JU KIM, SU HYUN JUNG, HYUN SEUNG RYU, JUN HYUK SEO
  • Patent number: 9623149
    Abstract: The present invention relates to a method for producing an acellular dermal matrix, and to an acellular dermal matrix produced by same, and more particularly, to a method for producing an acellular dermal matrix, in which sucrose is added to base ingredients consisting of glycerol, propylene glycol, and a base solvent or solution so as to produce a cryoprotectant, the solution is injected into the skin below the epidermis and dermis from which cells have been removed, and freeze-drying is then performed.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: April 18, 2017
    Assignee: CGBio Co., Ltd.
    Inventors: Wook Chun, Weon Ik Choi, Joon Pio Hong, Hyun Seung Ryu
  • Patent number: 9610378
    Abstract: The present invention relates to an antimicrobial wound dressing comprising chitosan-silver nanoparticles and a preparation method thereof The antimicrobial wound dressing is prepared by coating a wound dressing with chitosan and silver and drying the coated wound dressing and has an excellent property of releasing silver nanoparticles in a sustained manner.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: April 4, 2017
    Assignee: CG Bio Co., Ltd.
    Inventors: Hyun Seung Ryu, Jun Kyu Park, Jun Hyuk Seo, Young Koo Lee
  • Publication number: 20170087269
    Abstract: Provided is a charcoal dressing material and a method of manufacturing the same. The charcoal dressing material includes: a porous substrate having a plurality of pores; and a charcoal powder adhered to a surface of the porous substrate.
    Type: Application
    Filed: December 8, 2016
    Publication date: March 30, 2017
    Inventors: Hyun Seung RYU, Jun Hyuk SEO, Hee Jun PARK, Cho Hee PARK, Soon Gee HONG
  • Patent number: 9327049
    Abstract: The present invention relates to an anti-adhesion polymer composition capable of supporting growth factor, which effectively exhibits anti-adhesion function and, at the same time, has an excellent adhesive property so as to be able to easily and continuously adhere to a wound site, has antibacterial and hemostatic properties, and is composed of an injectable formulation suitable for use in minimally invasive surgery, laparoscopic surgery or the like. The anti-adhesion polymer composition capable of supporting growth factor comprises: 24-50 wt % of a polyethyleneglycol-polypropyleneglycol-polyethyleneglycol (PEG-PPG-PEG) block copolymer having a polyethyleneglycol (PEG) content of 65-85 wt % and a molecular weight of 6,000-20,000 Da; 0.03-5 wt % of gelatin; 0.03-5 wt % of chitosan; and distilled water.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: May 3, 2016
    Assignee: CG Bio Co., Ltd.
    Inventors: Jung Ju Kim, Jung Won So, Hyun Seung Ryu, Jun Hyuk Seo
  • Publication number: 20160051725
    Abstract: The present invention relates to a bone graft composition and a preparation method thereof, and more particularly to bone graft composition having excellent physical properties, which comprises a hydrogel comprising a combination of specific amounts of poloxamer and HPMC, and calcium phosphate compound particles, and a preparation method thereof.
    Type: Application
    Filed: March 28, 2014
    Publication date: February 25, 2016
    Inventors: Mi Young Ryu, Nam Yul Cho, Jun Hyuk Seo, Hyun Seung Ryu
  • Patent number: 9072817
    Abstract: The present invention relates to a bone-repair composition comprising a micro-pulverized demineralized bone matrix; a nonmicro-pulverized demineralized bone matrix; and a hydrating material. The bone-repair composition of the present invention provides easier injectability and shape-maintenance (handling), and exhibits excellent bone-repairing effects due to a large surface area of the micro-pulverized demineralized bone matrix and an early release of the bone growth factors, compared with conventional compositions comprising the nonmicro-pulverized demineralized bone matrix alone. It also has an advantage of being biocompatible and harmless to the human body because there is no use of synthetic materials.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: July 7, 2015
    Assignee: CG BIO Co., Ltd.
    Inventors: Seok Beom Song, Jung Won So, Hyun Seung Ryu, Byoung Suck Kim
  • Publication number: 20150182666
    Abstract: The present invention relates to a carrier for growth factor related to regeneration of bone tissues that is capable of arbitrarily controlling the delivery rate of growth factors related to bone regeneration and thus especially applicable to a bone void filler in the fields of the dental or orthopedic applications. The carrier for controlling the delivery rate of the growth factor in the present invention is composed of a hyaluronic acid hydrogel having a distribution of interconnected pores and a calcium phosphate microsphere being distributed in the pores of the hyaluronic acid hydrogel. The calcium phosphate microsphere having a porosity suitable for delivery of the growth factor is positioned into the pores of the cross-linked hyaluronic acid hydrogel to complete the carrier.
    Type: Application
    Filed: March 30, 2012
    Publication date: July 2, 2015
    Applicant: BIOALPHA INC.
    Inventors: Jung Ju Kim, Su Hyun Jung, Hyun Seung Ryu, Jun Hyuk Seo
  • Patent number: 9040156
    Abstract: This invention relates to whitlockite and a method for manufacturing the same. The method includes adding, to water, a calcium ion supplying material and a cation supplying material containing a cation (X) other than the calcium ion to prepare a cation aqueous solution, adding a phosphoric acid supplying material to the cation aqueous solution, and aging the cation aqueous solution including the phosphoric acid supplying material. As a result, whitlockite having high purity and high crystallinity can be mass produced using a simple process.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: May 26, 2015
    Assignee: SNU R&DB FOUNDATION
    Inventors: Kug Sun Hong, Ki Tae Nam, Hae Lin Jang, Hyun Seung Ryu, Kyoung Suk Jin
  • Patent number: 9029077
    Abstract: The present invention relates to a manufacturing method for fibrous demineralized bone matrix, the method comprising: (a) a step for subjecting a bone, separated from a body, to a primary demineralization in an acid solution for 1-5 hours; (b) a step for slicing the bone obtained in step (a) to a thickness of 0.1-3 mm, thus forming a sheet of bone; (c) a step for subjecting the sheet of bone obtained in step (b) to a secondary demineralization in an acid solution for 2-6 hours; and (d) a step for grinding the demineralized bone obtained in step (c).
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: May 12, 2015
    Assignee: CG Bio Co., Ltd.
    Inventors: Seok-Beom Song, Goo-Won Jeong, Jung-Won So, Han-Sol Seo, Hyun-Seung Ryu, Giue-Nam Kim, Byoung-Suck Kim
  • Patent number: 8961497
    Abstract: Provided is a portable vacuum generator that can effectively save battery power of a vacuum pump for absorbing exudates from a suction head that is connected to a tube, and a medical suction device using the same.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: February 24, 2015
    Assignee: Bioalpha Inc.
    Inventors: Hyun Seung Ryu, Joon Pio Hong, Myong Chul Park, Jun Kyu Park
  • Publication number: 20150010490
    Abstract: The present invention relates to an anti-adhesion polymer composition capable of supporting growth factor, which effectively exhibits anti-adhesion function and, at the same time, has an excellent adhesive property so as to be able to easily and continuously adhere to a wound site, has antibacterial and hemostatic properties, and is composed of an injectable formulation suitable for use in minimally invasive surgery, laparoscopic surgery or the like. The anti-adhesion polymer composition capable of supporting growth factor comprises: 24-50 wt % of a polyethyleneglycol-polypropyleneglycol-polyethyleneglycol (PEG-PPG-PEG) block copolymer having a polyethyleneglycol (PEG) content of 65-85 wt % and a molecular weight of 6,000-20,000 Da; 0.03-5 wt % of gelatin; 0.03-5 wt % of chitosan; and distilled water.
    Type: Application
    Filed: March 8, 2012
    Publication date: January 8, 2015
    Applicant: CG BIO CO., LTD.
    Inventors: Jung Ju Kim, Jung Won So, Hyun Seung Ryu, Jun Hyuk Seo
  • Publication number: 20140377331
    Abstract: The present invention relates to an antimicrobial wound dressing comprising chitosan-silver nanoparticles and a preparation method thereof The antimicrobial wound dressing is prepared by coating a wound dressing with chitosan and silver and drying the coated wound dressing and has an excellent property of releasing silver nanoparticles in a sustained manner.
    Type: Application
    Filed: December 28, 2012
    Publication date: December 25, 2014
    Inventors: Hyun Seung Ryu, Jun Kyu Park, Jun Hyuk Seo, Young Koo Lee
  • Publication number: 20140220142
    Abstract: The present invention provides a composition for bone regeneration comprising: particulate demineralized bone matrix; fibrous demineralized bone matrix; and a hydrate. In addition, it is preferable that the present invention comprises a demineralized solution-derived isolated product obtained by neutralizing a demineralized solution, separated from a demineralization process, and separating the precipitate generated.
    Type: Application
    Filed: October 11, 2011
    Publication date: August 7, 2014
    Applicant: CG BIO CO., LTD.
    Inventors: Seok-Beom Song, Soo-Yong Kim, Jung-Won So, Han-Sol Seo, Hyun-Seung Ryu, Giue-Nam Kim, Byoung-Suck Kim
  • Publication number: 20140208980
    Abstract: The present invention relates to a manufacturing method for fibrous demineralized bone matrix, the method comprising: (a) a step for subjecting a bone, separated from a body, to a primary demineralization in an acid solution for 1-5 hours; (b) a step for slicing the bone obtained in step (a) to a thickness of 0.1-3 mm, thus forming a sheet of bone; (c) a step for subjecting the sheet of bone obtained in step (b) to a secondary demineralization in an acid solution for 2-6 hours; and (d) a step for grinding the demineralized bone obtained in step (c).
    Type: Application
    Filed: October 11, 2011
    Publication date: July 31, 2014
    Applicant: CG BIO CO., LTD.
    Inventors: Seok-Beom Song, Goo-Won Jeong, Jung-Won So, Han-Sol Seo, Hyun-Seung Ryu, Giue-Nam Kim, Byoung-Suck Kim
  • Publication number: 20140044966
    Abstract: This invention relates to whitlockite and a method for manufacturing the same. The method includes adding, to water, a calcium ion supplying material and a cation supplying material containing a cation (X) other than the calcium ion to prepare a cation aqueous solution, adding a phosphoric acid supplying material to the cation aqueous solution, and aging the cation aqueous solution including the phosphoric acid supplying material. As a result, whitlockite having high purity and high crystallinity can be mass produced using a simple process.
    Type: Application
    Filed: October 4, 2012
    Publication date: February 13, 2014
    Applicant: SNU R&DB FOUNDATION
    Inventors: Kug Sun HONG, Ki Tae NAM, Hae Lin JANG, Hyun Seung RYU, Kyoung Suk JIN
  • Publication number: 20120329034
    Abstract: The present invention relates to a method for producing an acellular dermal matrix, and to an acellular dermal matrix produced by same, and more particularly, to a method for producing an acellular dermal matrix, in which sucrose is added to base ingredients consisting of glycerol, propylene glycol, and a base solvent or solution so as to produce a cryoprotectant, the solution is injected into the skin below the epidermis and dermis from which cells have been removed, and freeze-drying is then performed.
    Type: Application
    Filed: June 11, 2010
    Publication date: December 27, 2012
    Inventors: Wook Chun, Weon Ik Choi, Joon Pio Hong, Hyun Seung Ryu
  • Publication number: 20120259299
    Abstract: Provided is a portable vacuum generator that can effectively save battery power of a vacuum pump for absorbing exudates from a suction head that is connected to a tube, and a medical suction device using the same.
    Type: Application
    Filed: November 3, 2010
    Publication date: October 11, 2012
    Applicant: BIOALPHA INC.
    Inventors: Hyun Seung Ryu, Joon Pio Hong, Myong Chul Park, Jun Kyu Park