Patents by Inventor Hyung Hwan Baik

Hyung Hwan Baik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES CONTAINING FLUOXETINE AND VITAMIN C AS ACTIVE INGREDIENTS
    Publication number: 20200316020
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • Pharmaceutical composition for preventing and treating central nervous system diseases containing fluoxetine and vitamin C as active ingredients
    Patent number: 10772866
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: September 15, 2020
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASES CONTAINING FLUOXETINE AND VITAMIN C AS ACTIVE INGREDIENTS
    Publication number: 20160317492
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Application
    Filed: April 28, 2016
    Publication date: November 3, 2016
    Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • PHARMACEUTICAL COMPOSITION COMPRISING FLUOXETINE AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING BLOOD-BRAIN DISORDERS
    Publication number: 20140303256
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder comprising fluoxetine as an active ingredient. More particularly, fluoxetine inhibits the expressions of matrix metalloproteinase(MMP)-2, MMP-9, and MMP-12, which are reported to be related to blood-brain barrier (BBB) disruption and inflammatory reaction after spinal cord injury, specifically inhibits the activations of MMP-2 and MMP-9, inhibits the decomposition of ZO-1, the most representative tight junction protein, so as to maintain tight junction between endothelial cells and to protect blood-brain barrier thereby, inhibits the increase of blood-brain barrier permeability, and inhibits the expressions of chemoattractants of blood cells, such as CXCL-1, CXCL-2, CCL-2, CCL-3 and CCL-4 so as to reduce inflow of blood into spinal cord and recover exercise function which has been deteriorated by spinal cord injury.
    Type: Application
    Filed: October 19, 2012
    Publication date: October 9, 2014
    Applicant: UNIVERSITY INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Tae Hwan Oh, Hyung Hwan Baik, Jee Youn Lee