Patents by Inventor Hyung-Sik Kang

Hyung-Sik Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for astringin product
    Patent number: 9890409
    Abstract: Provided is a composition for producing astringin among metabolites of polydatin, wherein the astringin may be mass-produced by oxidizing the polydatin using a CYP102A1 chimera and mutants thereof as a catalyst, the CYP102A1 chimera being produced by fusing a reductase domain of a wild-type CYP102A1 which is a bacterial cytochrome P450 enzyme, with a heme domain of a CYP102A1 mutant.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: February 13, 2018
    Assignee: Industry Foundation of Chonnam National University
    Inventors: Chul-Ho Yun, Hyung-Sik Kang, Young-Hee Joung, Gun Su Cha
  • NOVEL COMPOSITION FOR ASTRINGIN PRODUCT
    Publication number: 20170073720
    Abstract: Provided is a composition for producing astringin among metabolites of polydatin, wherein the astringin may be mass-produced by oxidizing the polydatin using a CYP102A1 chimera and mutants thereof as a catalyst, the CYP102A1 chimera being produced by fusing a reductase domain of a wild-type CYP102A1 which is a bacterial cytochrome P450 enzyme, with a heme domain of a CYP102A1 mutant.
    Type: Application
    Filed: May 3, 2016
    Publication date: March 16, 2017
    Inventors: Chul-Ho Yun, Hyung-Sik Kang, Young-Hee Joung, Gun Su Cha
  • TREM-2 gene and protein as inhibitors of expression of GA733-2, and transgenic animals comprising the same and uses thereof
    Patent number: 8263822
    Abstract: Disclosed are a composition for inhibiting the expression of GA733-2 or for detecting GA733-2, which comprises TREM-2 gene or protein, a transgenic animal containing same, and a method using the same.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: September 11, 2012
    Assignee: GLO Biotech
    Inventors: Hyung-Sik Kang, Eun-Mi Kim, Dong-Hern Kim, Ha-Rim Choi, Eun-Hee Lee, Il-Soo Kim, Chang-Eon Park
  • TREM-2 GENE AND PROTEIN AS INHIBITORS OF EXPRESSION OF GA733-2, AND TRANSGENIC ANIMALS COMPRISING THE SAME AND USES THEREOF
    Publication number: 20100299767
    Abstract: Disclosed are a composition for inhibiting the expression of GA733-2 or for detecting GA733-2, which comprises TREM-2 gene or protein, a transgenic animal containing same, and a method using the same.
    Type: Application
    Filed: February 18, 2009
    Publication date: November 25, 2010
    Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
    Inventors: Hyung-Sik Kang, Eun-Mi Kim, Dong-Hern Kim, Ha-Rim Choi, Eun-Hee Lee, Il-Soo Kim, Chang-Eon Park
  • Differentiation regulating agent containing gene which regulating differentiation from stem cells into natural killer cells as effective ingredient
    Publication number: 20070042344
    Abstract: The present invention relates to a cell differentiation regulating agent containing a gene regulating differentiation from stem cells into natural killer cells as an effective ingredient, more precisely, a cell differentiation regulating agent containing a gene regulating differentiation from stem cells into premature natural killer cells as an effective ingredient and a screening method of the gene by taking advantage of SAGE. The gene of the present invention is a novel one that is confirmed not to be like any other known genes regulating differentiation from stem cells into natural killer cells. Though, the gene can be easily screened by SAGE and a natural killer cell differentiation-regulating agent containing the gene as an effective ingredient can be effectively used as an anticancer agent.
    Type: Application
    Filed: January 20, 2005
    Publication date: February 22, 2007
    Inventors: Inpyo Choi, Hyung-Sik Kang, Suk-Ran Yoon, Eun-Mi Kim
  • Method for inhibiting interleukin-6 production by administering extracts from root of Stephania tetrandra
    Patent number: 6162437
    Abstract: Method for inhibiting the production of interleukin-6 (hereinafter, referred to as "IL-6") in human body, which comprises administering extracts from a root of Stephania tetrandra S. Moore; and method for treating a patient of an immune disease caused by an overproduction of interleukin-6 by inhibiting the production of interleukin-6, which comprises administering extracts from a root of Stephania tetrandra S. Moore to the patient.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: December 19, 2000
    Assignee: Korea Institute of Science & Technology
    Inventors: Kwang-Ho Pyun, Inpyo Choi, Hyung-Sik Kang, Jung-Joon Lee, Young-Ho Kim
  • Method for inhibiting the production of interleukin-1 or tumor necrosis factor-.alpha. by administering acanthoic acid
    Patent number: 5900434
    Abstract: Process for the preparation of (-)-pimara-9(11),15-diene-19-oic acid(acanthoic acid) and pharmaceutical compositions comprising acanthoic acid useful for the treatment of diseases caused by an excessive production of interleukin-1 or tumor necrosis factor-.alpha..
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: May 4, 1999
    Assignee: Korea Institute of Science and Technology
    Inventors: Kwang-Ho Pyun, Inpyo Choi, Hyung-Sik Kang, Jung-Joon Lee, Young-Ho Kim