Abstract: The present invention relates to a novel oligonucleotide primer used for the synthesis of 5?-capped RNA. The novel oligonucleotide primer for RNA capping provided as Formula 1 in the present invention can be usefully utilized in the fields of nucleic acid therapeutic agents or vaccines.

Abstract: The present invention relates to a pyrrolopyridine derivative, a racemate thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and use thereof. The compound of the present invention has high selectivity and bioactivity against human immunodeficiency virus (HIV), and low toxicity, thus being useful as a therapeutic agent for viral infection, particularly human immunodeficiency virus (HIV) infection.

Abstract: The present disclosure relates to a novel nucleoside or nucleotide derivative, a racemate thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating viral infection-associated diseases, containing the same as an active ingredient.

Abstract: Provided is a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; a pharmaceutical composition for the prevention or treatment of Sirt6-associated diseases, including as an active ingredient, a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; and a method for treating Sirt6-associated diseases including administering a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof to a subject in need.

Abstract: The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Abstract: The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Abstract: The present invention relates to a novel imidazotriazinone or imidazopyrazinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Abstract: The present invention relates to a novel triazolopyrimidinone or triazolopyridinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.

Abstract: In an alternator having a vacuum pump capable of improving a cooling characteristic, and having a rotary shaft supported by bearings installed in a rear bracket of the alternator, a housing of the vacuum pump has vanes and a rotation rotor is installed on the rotary shaft. A pump bracket is assembled to a lower portion of the housing and includes a packing inserted in an outer circumferential portion of a center shaft hole of the pump bracket for implementing a sealing operation in surface-contact with the rear bracket. A certain space is formed between the packing and the shaft hole for preventing a heat transfer, and a heat radiating unit is installed in a lower surface of the pump bracket.

Abstract: The present invention relates to an alternator having a vacuum pump capable of improving a cooling characteristic, and in particular to an alternator having a vacuum pump capable of improving a cooling characteristic which is capable of restraining a heat transfer to a bracket and brush of an alternator by effectively radiating a heat of a vacuum pump by providing a cooling unit which performs a heat sink function in a bracket installed in one side of a housing of a vacuum pump and capable of preventing a heat-degradation of oil supplied to the brush and into the vacuum pump in a vehicle vacuum pump which is installed in a portion of an alternator of a vehicle and which supports an operation of a brake, for thereby significantly enhancing a durability of the brush.