Abstract: Provided is a composition comprising sonosensitive liposomes for penetrating the blood-brain barrier, wherein the sonosensitive liposomes have excellent drug loading efficiency and ultrasound-induced drug release effect and can effectively penetrating the blood-brain barrier during ultrasound stimulation, and the sonosensitive liposomes can circulate in the body for a long time, and thus have better blood-brain barrier penetration efficiency, a high affinity for brain tumor cells, and excellent delivery effect to tumor sites and can be used as a drug delivery system for delivering brain disease therapeutic agents and the like to the brain.

Abstract: The present invention relates to novel microspheres using an anionic polymer, a preparation method thereof, a composition, and the like, and the present invention is used for a method for performing a vascular embolization and/or necrosing cancer cells by blocking major blood vessels that supply nutrients to cancer cells to induce an embolic effect, and thus may be used for the treatment of patients with cancer.

Abstract: The present invention relates to a sonosensitive liposome and a method for preparing same, and the sonosensitive liposome, according to the present invention, increases the delivery efficiency of an encapsulated drug and, by being used in combination with sonication, is expected to exhibit various functions in the field of cancer treatment and drug delivery carriers through an improved drug delivery effect by means of targeting cancer cells.

Abstract: The present invention relates to an ultrasound contrast agent with drug-encapsulating nanoparticles and a method for preparing the same that increase drug delivery capabilities and drug penetration effects. According to the present invention, exposure to the focussed ultrasound triggers the cavitation of an ultrasound contrast agent, resulting in the local release of drug-encapsulating nanoparticles, which are conjugated onto the surface of the ultrasound contrast agent, and enhanced penetration of nanoparticles and drug delivery capabilities. Moreover, the present invention simultaneously and selectively diagnoses and treats cancers by conjugation cancer-targeting ligands on the surface of nanoparticles.