Patents by Inventor Hyung-Gyoo Kang

Hyung-Gyoo Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted polymerized nanoparticles for cancer treatment
    Patent number: 11337924
    Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: May 24, 2022
    Assignees: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Tim Triche, Hyung-Gyoo Kang
  • TARGETED POLYMERIZED NANOPARTICLES FOR CANCER TREATMENT
    Publication number: 20190365650
    Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.
    Type: Application
    Filed: June 18, 2019
    Publication date: December 5, 2019
    Applicants: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Tim Triche, Hyung-Gyoo Kang
  • Targeted polymerized nanoparticles for cancer treatment
    Patent number: 10369104
    Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: August 6, 2019
    Assignees: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Tim Triche, Hyung-Gyoo Kang
  • Compositions and methods for treating ewing sarcoma
    Patent number: 9956176
    Abstract: Provided herein are compositions and methods for treating cancer in a subject in need thereof. The methods include using hybrid polymerized liposomal nanoparticles comprising, both polymerizable lipids and non-polymerizable lipids. The nanoparticles further comprise targeting agents and therapeutic agents.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: May 1, 2018
    Assignees: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Timothy Triche, Hyung-Gyoo Kang, Sheetal Mitra
  • COMPOSITIONS AND METHODS FOR TREATING EWING SARCOMA
    Publication number: 20170143630
    Abstract: Provided herein are compositions and methods for treating cancer in a subject in need thereof. The methods include using hybrid polymerized liposomal nanoparticles comprising, both polymerizable lipids and non-polymerizable lipids. The nanoparticles further comprise targeting agents and therapeutic agents.
    Type: Application
    Filed: January 23, 2017
    Publication date: May 25, 2017
    Applicants: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Timothy Triche, Hyung-Gyoo Kang, Sheetal Mitra
  • TARGETED POLYMERIZED NANOPARTICLES FOR CANCER TREATMENT
    Publication number: 20170020816
    Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.
    Type: Application
    Filed: April 1, 2015
    Publication date: January 26, 2017
    Applicants: Children's Hospital Los Angeles, Nanovalent Pharmaceuticals, Inc.
    Inventors: Jon O. Nagy, Tim Triche, Hyung-Gyoo Kang