Patents by Inventor HYUNGWOOK LIM

HYUNGWOOK LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for immunooncology
    Patent number: 11851659
    Abstract: The present disclosure is directed to genome editing systems, reagents and methods for immunooncology.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: December 26, 2023
    Assignees: Novartis AG, Intellia Therapeutics, Inc.
    Inventors: Jennifer Brogdon, Ming-Wei Chen, Hyungwook Lim, Yi Yang, Morag Stewart, Sarah Hesse
  • METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
    Publication number: 20230256017
    Abstract: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.
    Type: Application
    Filed: February 26, 2021
    Publication date: August 17, 2023
    Inventors: Jennifer BROGDON, Glenn DRANOFF, Michael R. GREENE, Anniesha HACK, Olja KODRASI, Elizabeth Dorothy PRATICO, Andrew PRICE, Andrew Marc STEIN, Amy RAYO, Jennifer YANG, Brian Walter GRANDA, Attilio BONDANZA, Boris ENGELS, Hyungwook LIM, Akash SOHONI, Louise TREANOR, Xu ZHU, Carla GUIMARAES, Shyamali JAYASHANKAR, Sandeep Tharian KOSHY, Regis CEBE, Michael BARDROFF, Sandra MILLER
  • METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
    Publication number: 20230174933
    Abstract: This disclosure provides methods of making immune effector cells (for example, T cells, NK cells) that comprise (i) a nucleic acid molecule that encodes a controllable chimeric antigen receptor (CCAR) or (ii) a nucleic acid molecule that encodes a CAR and a regulatory molecule, and compositions generated by such methods.
    Type: Application
    Filed: February 26, 2021
    Publication date: June 8, 2023
    Inventors: Jennifer BROGDON, Seth CARBONNEAU, Glenn DRANOFF, Michael R. Greene, Anniesha HACK, Marc Horst Peter HILD, Olja KODRASI, Elizabeth Dorothy PRATICO, Andrew PRICE, Andrew Marc STEIN, Attilio BONDANZA, Boris ENGELS, Carla Patricia Pinto GUIMARAES, Hyungwook LIM, Sujata SHARMA, Akash SOHONI, Louise TREANOR, Xu ZHU
  • METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS
    Publication number: 20220364055
    Abstract: The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.
    Type: Application
    Filed: August 30, 2019
    Publication date: November 17, 2022
    Inventors: Louise Treanor, Michael R. Greene, Jennifer Brogdon, Boris Engels, Glenn Dranoff, Olja Kodrasi, Hyungwook Lim, Akash Sohoni, Elizabeth Dorothy Pratico, Anniesha Hack, Aida Abujoub, Tony Fleming, Lu Huang, Connie Hong, John Blankenship, Brian Holmberg, Chonghui Zhang, Dexiu Bu, Andrew Price, Xu Zhu, Andrew Stein, Attilio Bondanza
  • CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
    Publication number: 20210220404
    Abstract: The invention provides immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions and methods thereof.
    Type: Application
    Filed: November 25, 2020
    Publication date: July 22, 2021
    Inventors: Aida Abujoub, John Blankenship, Attilio Bondanza, Jennifer Brogdon, Dexiu Bu, Serena De Vita, Glenn Dranoff, Boris Engels, Tony Fleming, Brian Walter Granda, Michael R. Greene, Carla Patricia Guimaraes, Anniesha Hack, Brian Holmberg, Connie Hong, Lu Huang, Olja Kodrasi, Joni Waiee Lam, Hyungwook Lim, Elizabeth Dorothy Pratico, Andrew Price, Akash Sohoni, Andrew Marc Stein, Louise Treanor, Chonghui Zhang, Xu Zhu
  • COMPOSITIONS AND METHODS FOR IMMUNOONCOLOGY
    Publication number: 20210071182
    Abstract: The present disclosure is directed to genome editing systems, reagents and methods for immunooncology.
    Type: Application
    Filed: March 21, 2018
    Publication date: March 11, 2021
    Applicants: Novartis AG, Intellia Therapeutics, Inc.
    Inventors: Jennifer BROGDON, Ming-Wei CHEN, Hyungwook LIM, Yi YANG, Morag STEWART, Sarah HESSE
  • Use of SIRT1 activators or inhibitors to modulate an immune response
    Patent number: 8748464
    Abstract: The present disclosure provides a method of increasing an immune response in an individual, the method involving administering to an individual in need thereof an inhibitor of SIRT1. The present disclosure provides a method of reducing an immune response, e.g., to treat chronic immune hyperactivity, the method generally involving administering to an individual in need thereof an activator of SIRT1. The present disclosure provides a method of modulating activation and differentiation of CD4+ T cells.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: June 10, 2014
    Assignee: The J. David Gladstone Institutes
    Inventors: Eric M. Verdin, Melanie Ott, Hye-Sook Kwon, Hyungwook Lim
  • Use of SIRT1 Activators or Inhibitors to Modulate an Immune Response
    Publication number: 20100330114
    Abstract: The present disclosure provides a method of increasing an immune response in an individual, the method involving administering to an individual in need thereof an inhibitor of SIRT1. The present disclosure provides a method of reducing an immune response, e.g., to treat chronic immune hyperactivity, the method generally involving administering to an individual in need thereof an activator of SIRT1. The present disclosure provides a method of modulating activation and differentiation of CD4+T cells.
    Type: Application
    Filed: July 16, 2010
    Publication date: December 30, 2010
    Inventors: ERIC M. VERDIN, MELANIE OTT, HYE-SOOK KWON, HYUNGWOOK LIM