Abstract: This application pertains to a hairpin nucleic acid molecule capable of modulating expression of a target gene and a use thereof. A nucleic acid molecule according to an embodiment can modulate expression of a target gene in a specific manner for cells in which a miRNA hybridizable therewith is present, finding advantageous applications in compositions for regulating expression of a target gene or pharmaceutical compositions for treating diseases.

Abstract: This application pertains to a hairpin nucleic acid molecule capable of modulating expression of a target gene and a use thereof. A nucleic acid molecule according to an embodiment can modulate expression of a target gene in a specific manner for cells in which a miRNA hybridizable therewith is present, finding advantageous applications in compositions for regulating expression of a target gene or pharmaceutical compositions for treating diseases.

Abstract: The present invention relates to a self-priming hairpin-mediated isothermal amplification (SP-HAMP) and, more specifically, to a hairpin probe having a self-priming structure, which is for detecting a target nucleic acid and can be used in the nucleic acid isothermal amplification, and to a method for detecting a target nucleic acid by using same. The SP-HAMP technique according to the present invention is convenient due to no need of a separate primer with a complicated design required in existing LAMP technology, has improved efficiency of detection compared with existing LAMP reactions, and can detect DNA as well as RNA as a target nucleic acid, and therefore the technique according to the present invention can be applied in a wider variety of fields.

Abstract: A pressure sensing insole according to an embodiment of the present invention includes: a first electrode layer including a first conductive region; a first adhesive layer disposed on the first electrode layer and including an insulating region; an intermediate layer disposed on the first adhesive layer; a second adhesive layer disposed on the intermediate layer and including an insulating region; and a second electrode layer disposed on the second adhesive layer and including a second conductive region.

Abstract: The present invention relates to a detection method for detecting a target RNA contained in a sample with high sensitivity by using nicking/extension chain reaction system-based isothermal nucleic acid amplification (NESBA) that uses activity of a cleavage enzyme and a DNA polymerase. The NESBA of the present invention is a new concept isothermal target RNA detection method that realizes higher amplification efficiency than the existing NASBA technology and is deemed to be utilizable as a new concept diagnosis technology that can replace conventional target RNA detection technologies.

Abstract: The present invention relates to a detection method for detecting a target RNA contained in a sample with high sensitivity by using nicking/extension chain reaction system-based isothermal nucleic acid amplification (NESBA) that uses activity of a cleavage enzyme and a DNA polymerase. The NESBA of the present invention is a new concept isothermal target RNA detection method that realizes higher amplification efficiency than the existing NASBA technology and is deemed to be utilizable as a new concept diagnosis technology that can replace conventional target RNA detection technologies.

Abstract: The present invention relates to a detection method for detecting a target RNA contained in a sample with high sensitivity by using nicking/extension chain reaction system-based isothermal nucleic acid amplification (NESBA) that uses activity of a cleavage enzyme and a DNA polymerase. The NESBA of the present invention is a new concept isothermal target RNA detection method that realizes higher amplification efficiency than the existing NASBA technology and is deemed to be utilizable as a new concept diagnosis technology that can replace conventional target RNA detection technologies.

Abstract: Provided is a glass product manufacturing apparatus. The glass product manufacturing apparatus includes a furnace including a gas heating zone and an electric heating zone, a first heat exchange module configured to recover heat from the furnace, and a pump configured to drive flow of a heat transfer medium fluid passing through the first heat exchange module, wherein at least a part of the first heat exchange module is thermally coupled with at least a part of an external surface of the electric heating zone. The glass product manufacturing apparatus may reduce defect rate while exhibiting high energy efficiency.

Abstract: The present invention relates to a method of preparing nucleic acid-inorganic hybrid nanoflowers, which comprises allowing a nucleic acid to react with a solution of a metal ion-containing compound at room temperature, thereby forming a complex between the metal ion and the nitrogen atom of an amide bond or amine group present in the nucleic acid. According to the present invention, organic-inorganic hybrid nanoflower structures may be synthesized using nucleic acid in a simple manner under an environmentally friendly condition without any toxic chemical substance. The produced organic-inorganic hybrid nanoflower structures show a high DNA encapsulation yield, have resistance against nuclease, and show significantly increased peroxidase activity. Thus, these nanoflower structures may be widely used as a gene therapy carrier and in biosensing technology.

Abstract: A pressure sensing element may include: an intermediate layer having a structure in which at least two functional layers are stacked on each other; a first electrode layer including a plurality of first electrode patterns; and a second electrode layer to overlap the first electrode layer with the intermediate layer between the first and second electrode layers. Among the two functional layers, the first functional layer has a thickness linearly varying in a first pressure section, and the second functional layer has a thickness linearly varying in a second pressure section. The maximum pressure in the first pressure section is lower than that in the second pressure section, and the minimum pressure in the second pressure section is included in the first pressure section.

Abstract: A glass product manufacturing apparatus and a method of manufacturing glass products are disclosed. The glass product manufacturing apparatus includes a melting vessel, a support grating configured to support an outer wall of the melting vessel, a cooling module configured to cool the outer wall of the melting vessel, on the support grating, and a support frame detachably fastened to the support grating to limit a movement of the support grating. By using the glass product manufacturing apparatus and the method of manufacturing glass products, high energy efficiency is maintained even when operating, and a defect rate is reduced.

Abstract: A pressure detecting sensor according to an embodiment of the present invention comprises: a first electrode layer including a plurality of signal electrodes arranged in a first region and a plurality of wiring electrodes arranged in a second region and connected to the plurality of signal electrodes, the first electrode layer being made of a conductive fiber; an elastic dielectric layer arranged in the first region; and a second electrode layer arranged in the elastic dielectric layer, the second electrode layer being made of a conductive fiber.

Abstract: The present invention relates to a target nucleic acid-detecting method using hairpin probe-assisted isothermal probe amplification (HIPAmp). According to the present invention, the method has the advantage of being able to conduct detection with respect to general-use target nucleic acids by solving the problem with the conventional isothermal nucleic acid amplification technique EXPAR with regard to limited uses of target nucleic acids.

Abstract: The present invention relates to an isothermal nucleic acid amplification technique based on a three-way junction structure that is formed as a ThIsAmp template; a ThIsAmp primer; and a nucleic acid are associated with each other through a hybridization reaction. Beyond the limitation of the conventional EXPAR technique, that is, the restricted application range that the EXPAR can be used only for detecting short target nucleic acids having a 3?-OH end, the method according to the present invention can detect target nucleic acids at excellent efficiency without being limited to kinds of target nucleic acids.

Abstract: A pressure detection sensor according to one embodiment of the present invention includes a first electrode layer including a channel portion configured to output a sensing signal and a wiring portion connected to the channel portion, a first elastic dielectric layer disposed on the first electrode layer, a second electrode layer disposed on the first elastic dielectric layer at a position corresponding to the channel portion, a second elastic dielectric layer disposed on the second electrode layer, and a third electrode layer disposed on the second elastic dielectric layer, wherein, when a pressure is applied to the third electrode layer, capacitances of the first elastic dielectric layer and the second elastic dielectric layer are changed.

Abstract: A pressure sensing insole according to an embodiment of the present invention includes: a first electrode layer including a first conductive region; a first adhesive layer disposed on the first electrode layer and including an insulating region; an intermediate layer disposed on the first adhesive layer; a second adhesive layer disposed on the intermediate layer and including an insulating region; and a second electrode layer disposed on the second adhesive layer and including a second conductive region.

Abstract: A sensor device may include an elastic dielectric; a sensing unit including a first wiring and a second wiring for outputting sensing signals, and a flexible printed circuit board provided with a first connection terminal to which the first wiring is connected, and with a second connection terminal to which the second wiring is connected. The first wiring is formed on one surface of the dielectric and may be connected to the first connection terminal. The second wiring is formed on another surface of the dielectric facing the surface on which the first wiring is formed and may be connected to the second connection terminal.

Abstract: A sensor device may detect pressure. The sensor device may comprise: an elastic dielectric; a first wiring formed on one surface of the elastic dielectric; a second wiring formed on another surface of the elastic dielectric facing the surface on which the first wiring is formed; and a flexible printed circuit board, which is connected to the first wiring and the second wiring, for receiving signals transferred from the first wiring and the second wiring.

Abstract: A direction detecting device according to an exemplary embodiment of the present invention includes; a structure having at least two through-holes passing through an upper surface and a lower surface thereof; and at least two electrode units inserted into the at least two through-holes and each including a dielectric layer, a first electrode layer disposed on an upper surface of the dielectric layer and exposed at the upper surface of the structure, and a second electrode layer disposed on a lower surface of the dielectric layer and exposed at the lower surface of the structure.

Abstract: A pressure sensor formed in a sheet type is provided, including conductive fibers, nonconductive fibers, and piezoresistive fibers, which are woven together, wherein the pressure sensor includes a first electrode layer including the conductive fibers and the nonconductive fibers, a second electrode layer including the conductive fibers and the nonconductive fibers, and a piezoresistive layer including the piezoresistive fibers and disposed between the first electrode layer and the second electrode layer.