Abstract: A light emitting element includes an emission stacked pattern and an insulating film. The emission stack pattern includes a first conductive semiconductor layer, an active layer disposed on the first conductive semiconductor layer, and a second conductive semiconductor layer disposed on the active layer. The insulating film surrounds an outer surface of the emission stacked pattern and has a non-uniform thickness.

Abstract: The present invention relates to a polysubstituted imidazolo[4,5-c][1,2]thiazine derivative and a use of an agent comprising same as an active agent, which is useful for infectious diseases associated with vascular inflammation caused by HMGB1 protein activity. It has been found that the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative of the present invention increases the sepsis survival rate as a result of searching for antiseptic effects through CLP-induced sepsis animal experiments. Accordingly, the agent comprising the polysubstituted imidazolo[4,5-c][1,2]thiazine derivative or a pharmaceutically acceptable salt thereof as an active agent may be advantageously used as a therapeutic agent for infectious diseases and vascular inflammatory diseases including sepsis caused by HMGB1 protein activity.

Abstract: Provided is a defect analysis device which may include a light source that irradiates an analysis target layer of an element with light, a position adjuster that adjusts a position in the analysis target in the analysis target to be irradiated with the light, a detector that measures a current value of current flowing between a source area of the element electrically connected to one end of the analysis target layer and a drain area of the element electrically connected to the other end of the analysis target layer in the element, and an analyzer that acquires quantitative data related to a defect in the analysis target layer on the basis of the current value in which, in a first mode, a plurality of areas of the analysis target layer are sequentially irradiated with the light.

Abstract: A balloon type retinal stimulation device includes: a substrate unit having an insertion portion provided to be inserted into an eyeball; and a stimulation unit that is provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is provided to be expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion is deformed to match a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed.

Abstract: A balloon type retinal stimulation device includes: a substrate unit having an insertion portion to be inserted into an eyeball; and a stimulation unit provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion matches a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed.

Abstract: The present invention provides a selective bonding method of polymer substrates. The present invention allows selective interfacial bonding between a polymer substrate and a parylene layer by using a mask pattern and plasma treatment, and enables the formation of a three-dimensional structure by injecting a fluid into a non-bonded area.

Abstract: A balloon type retinal stimulation device includes: a substrate unit having an insertion portion provided to be inserted into an eyeball; and a stimulation unit that is provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is provided to be expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion is deformed to match a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed.

Abstract: A drug delivery device and a method for manufacturing the same, and more specifically, a drug delivery device that can deliver a drug to a biological tissue while minimizing damage thereto and can come into close contact with the biological tissue to be able to measure an electrical signal of or apply electrical stimulation to the biological tissue and a method for manufacturing the drug delivery device are proposed. The drug delivery device includes a substrate unit that is inserted into a human body and has a porous insertion portion having one or more discharge voids. The insertion portion is provided to be deformable to match a shape of a biological tissue while expanding and contracting as a drug is injected into and discharged from an inside of the injection portion.

Abstract: The present invention provides a selective bonding method of polymer substrates. The present invention allows selective interfacial bonding between a polymer substrate and a parylene layer by using a mask pattern and plasma treatment, and enables the formation of a three-dimensional structure by injecting a fluid into a non-bonded area.