Abstract: The present disclosure relates to an optical transfer device for tissue treatment. An optical transfer device of the present disclosure includes an optical probe having a light divergence part at the longitudinal end thereof, and a coating part configured to surround the optical probe, wherein the coating part includes a light diffusion part formed at the end thereof configured to cover the light divergence part, the light diffusion part having multiple grooves formed thereon.

Abstract: Techniques are provided for controlling an output laser pulse signal of a medical device. A control device defines a time duration of capacitive discharge to a laser device. The time duration corresponds to an intended energy of the output laser pulse signal. The control device generates a plurality of sub-pulse control signals. The sub-pulse control signals define a series of capacitive discharge events of the capacitor bank. The control device modulates one or more of a sub-pulse control signal period or a sub-pulse time duration of the sub-pulse control signals to modify the capacitive discharge of the capacitor bank to the laser device during the time duration.

Abstract: A capsulorhexis device is inserted into an incision site of a cornea to make an incision in an anterior capsule surrounding a crystalline lens. The capsulorhexis device includes a loop having elasticity and conductivity; a moving member having one end fixed and coupled to the loop; an insertion guide configured so that, while the incision is being made in the crystalline lens capsule, a front end thereof is inserted into the incision site of the cornea; and a housing having one end coupled to a rear end of the insertion guide, wherein the loop is housed in the housing and, to make the incision in the crystalline lens capsule, slides in the housing together with the moving member to pass through the insertion guide and be deployed into an anterior chamber of the eye.

Abstract: A substrate processing apparatus includes a photoresist coater applying a photoresist film on a substrate, a humidifier increasing an amount of moisture in an ambient to which the photoresist film on the substrate is exposed, and an exposer irradiating the photoresist film exposed to the ambient having the increased amount of moisture with light. The humidifier is disposed between the photoresist coater and the exposer.

Abstract: Provided is a ceiling storage system capable of correcting a working position and constantly checking stability of a structure by detecting an amount of change in a facility. According to the ceiling storage system, a transport vehicle moves to an upper portion of a first storage area of a plurality of storage areas in a state of gripping an article, and the transport vehicle measures a first distance value between the transport vehicle and the first storage area using a distance sensor and measures a relative position value between the transport vehicle and the first storage area using a vision sensor, before unloading the article from the first storage area.

Abstract: A method of making an organ or tissue comprises: (a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers comprising one or the other of said support polymer or said cell-containing composition, to thereby produce provide a composite three dimensional structure containing both structural support regions and cell-containing regions. Apparatus for carrying out the method and composite products produced by the method are also described.

Abstract: The present invention relates to a real-time parathyroid imaging device, and a real-time parathyroid imaging device for displaying only a parathyroid in a thyroid with a separate mark, the real-time parathyroid imaging device including: a light source configured to emit light to a thyroid and excite a parathyroid; a detector configured to detect an emission spectrum of the parathyroid excited and emitted by the light source; an excitation filter disposed in front of the light source; and an emission filter disposed in front of the detector. When central Compartment Neck Dissection (CCND) for thyroidectomy is performed, the present invention clearly marks a parathyroid by an autofluorescent image, thereby allowing a surgeon to more simply and safely perform the CCND while leaving the parathyroid.

Abstract: A laser resonator includes a gain medium that produces light from pump energy and a variable light attenuator, which receives light and emits either (i) a first light including a continuous series of micropulses, or (ii) a second light including a series of macropulses at spaced time intervals, where each macropulse includes a series of micropulses. Each micropulse has a duration of 0.1 to 10 microseconds, and a duration of each macropulse is less than the time interval between each macropulse, and the micropulses have a frequency of 5 kHz to 40 kHz.

Abstract: The present invention provides an optical irradiation apparatus including: a dual laser light source unit which simultaneously or selectively outputs multiple light sources created with different outputs; an optical fiber which is connected to the dual laser light source unit, receives the light outputted from the dual laser light source unit, and emits the received light through an embossed end surface; and an inflatable balloon catheter which is formed to surround the embossed end surface of the optical fiber and expands constricted tissue. With the present invention, it is possible to effectively treat constricted tissue during a procedure of performing an anticancer therapy on entire human bodies with various types of cancers, and it is possible to mitigate patient's pain by reducing a relapse rate of stenosis after the photothermal therapy.

Abstract: A laser resonator includes a gain medium that produces light from pump energy and a variable light attenuator, which receives light and emits either (i) a first light including a continuous series of micropulses, or (ii) a second light including a series of macropulses at spaced time intervals, where each macropulse includes a series of micropulses. Each micropulse has a duration of 0.1 to 10 microseconds, and a duration of each macropulse is less than the time interval between each macropulse, and the micropulses have a frequency of 5 kHz to 40 kHz.

Abstract: A method of making an organ or tissue comprises: (a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers comprising one or the other of said support polymer or said cell-containing composition, to thereby produce provide a composite three dimensional structure containing both structural support regions and cell-containing regions. Apparatus for carrying out the method and composite products produced by the method are also described.

Abstract: The present invention provides an optical irradiation apparatus including: a dual laser light source unit which simultaneously or selectively outputs multiple light sources created with different outputs; an optical fiber which is connected to the dual laser light source unit, receives the light outputted from the dual laser light source unit, and emits the received light through an embossed end surface; and an inflatable balloon catheter which is formed to surround the embossed end surface of the optical fiber and expands constricted tissue. With the present invention, it is possible to effectively treat constricted tissue during a procedure of performing an anticancer therapy on entire human bodies with various types of cancers, and it is possible to mitigate patient's pain by reducing a relapse rate of stenosis after the photothermal therapy.

Abstract: A method of making an organ or tissue comprises: (a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers comprising one or the other of said support polymer or said cell-containing composition, to thereby produce provide a composite three dimensional structure containing both structural support regions and cell-containing regions. Apparatus for carrying out the method and composite products produced by the method are also described.

Abstract: Techniques are provided for controlling an output laser pulse signal of a medical device. A control device defines a time duration of capacitive discharge to a laser device. The time duration corresponds to an intended energy of the output laser pulse signal. The control device generates a plurality of sub-pulse control signals. The sub-pulse control signals define a series of capacitive discharge events of the capacitor bank. The control device modulates one or more of a sub-pulse control signal period or a sub-pulse time duration of the sub-pulse control signals to modify the capacitive discharge of the capacitor bank to the laser device during the time duration.

Abstract: Provided are an apparatus and method for sterilizing an internal channel surface of an endoscope, and more particularly, to an apparatus and method for sterilizing an internal channel surface of an endoscope, in which ultrasonic and infrared rays are irradiated to an internal channel of the endoscope to partially or entirely sterilize and removing a biofilm generated on the internal channel surface of the endoscope during a procedure or diagnosis.

Abstract: Disclosed is a process of manufacturing cell spheroids using a bioink. More particularly, provided is a method of manufacturing a cell spheroid, the method including extruding a first bioink including an alginate; extruding a second bioink including cells into the extruded first bioink; adding a calcium chloride (CaCl2) solution to the alginate included in the first bioink; and dissolving the second bioink, present in the first bioink, in a cell culture medium to form a cell spheroid from the cells.

Abstract: Embodiments of a surgical laser system comprise a laser source (102), a laser fiber (104), a photodetector (106) and a controller (108). The laser source is configured to generate laser energy (1 10). The laser fiber is optically coupled to the laser source and is configured to discharge the laser energy generated by the laser source. The photodetector is configured to generate an output signal (1 12) that is indicative of an intensity level of electromagnetic energy feedback (114) that is produced in response to the discharge of the laser energy. The controller is configured to control the laser source based on the output signal.

Abstract: The present invention relates to an energy delivery device for expanding a tubular organ, the energy delivering device delivering energy to a tubular organ by an optical fiber for treatment and expanding a tissue in the tubular organ, the device comprising a light diffusing optical fiber connected between a laser device and a fixing tip and delivering light; a contraction unit having one end connected to the fixing tip and arranged in a circumference of an end of the light diffusing optical fiber; a movement unit closely adhered to the other end of the contraction unit, in which the light diffusing optical fiber is inserted; and an expansion adjustment unit adjusting a moving distance of the movement unit and expanding the contraction unit in a radial direction while contracting the contraction unit.

Abstract: Embodiments of a surgical laser systems may include a laser source configured to generate a laser energy; a laser fiber optically coupled to the laser source to discharge laser energy; a photodetector configured to generate an output signal indicative of an intensity level of electromagnetic energy feedback produced in response to the discharge of the laser energy; and a controller configured to control the laser source based on the output signal. Embodiments of a method of controlling a surgical laser system also are disclosed, wherein laser energy is generated using a laser source and discharged through a laser fiber. Electromagnetic energy feedback produced in response to discharging the laser energy is delivered to a photodetector. An output signal from the photodetector is analyzed using a controller. The laser source is controlled in response to analyzing an output signal using the controller.

Abstract: The present invention relates to a real-time parathyroid imaging device, and a real-time parathyroid imaging device for displaying only a parathyroid in a thyroid with a separate mark, the real-time parathyroid imaging device including: a light source configured to emit light to a thyroid and excite a parathyroid; a detector configured to detect an emission spectrum of the parathyroid excited and emitted by the light source; an excitation filter disposed in front of the light source; and an emission filter disposed in front of the detector. When central Compartment Neck Dissection (CCND) for thyroidectomy is performed, the present invention clearly marks a parathyroid by an autofluorescent image, thereby allowing a surgeon to more simply and safely perform the CCND while leaving the parathyroid.