Patents by Inventor I. Caroline Le Poole

I. Caroline Le Poole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210024599
    Abstract: Methods of treating autoimmune diseases, such as vitiligo, by using compositions comprising DNA encoding a variant inducible heat shock protein 70 (HSP70i) having a mutation in the dendritic cell binding region thereof (HSP70i435-447) or an isolated variant gene product in the form of HSP70i with a modification in the dendritic cell activating region thereof (HSP70i435-447).
    Type: Application
    Filed: October 6, 2020
    Publication date: January 28, 2021
    Inventors: I. Caroline Le Poole, Jose Alejandro Guevara, Andrew Zloza
  • Patent number: 10829526
    Abstract: Methods of treating autoimmune diseases, such as vitiligo, by using compositions comprising DNA encoding a variant inducible heat shock protein 70 (HSP70i) having a mutation in the dendritic cell binding region thereof (HSP70i435-447) or an isolated variant gene product in the form of HSP70i with a modification in the dendritic cell activating region thereof (HSP70i435-447).
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: November 10, 2020
    Assignee: LOYOLA UNIVERSITY OF CHICAGO
    Inventors: I. Caroline Le Poole, Jose Alejandro Guevara, Andrew Zloza
  • Publication number: 20180066030
    Abstract: Methods of treating autoimmune diseases, such as vitiligo, by using compositions comprising DNA encoding a variant inducible heat shock protein 70 (HSP70i) having a mutation in the dendritic cell binding region thereof (HSP70i435-447) or an isolated variant gene product in the form of HSP70i with a modification in the dendritic cell activating region thereof (HSP70i435-447).
    Type: Application
    Filed: October 24, 2017
    Publication date: March 8, 2018
    Inventors: I. Caroline Le Poole, Jose Alejandro Guevara, Andrew Zloza
  • Publication number: 20140341935
    Abstract: A vaccine and method of treatment suitable for treating autoimmune diseases, such as Vitiligo, by using variant peptides representing a sequence of amino acids found in heat shock protein 70. The vaccine includes a peptide derived from inducible heat shock protein 70 and a plasmid containing a full inducible heat shock protein 70 DNA sequence encoding the peptide.
    Type: Application
    Filed: August 30, 2012
    Publication date: November 20, 2014
    Applicant: Loyola University Chicago
    Inventors: I. Caroline Le Poole, Jose Alejandro Guevara-Patino, Andrew Zloza