Patents by Inventor I-Chen Sun

I-Chen Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylated betulin and dihydrobetulin derivatives, preparation thereof and use thereof
    Patent number: 6172110
    Abstract: Betulin and dihydrobetulin acyl derivatives according to the present invention have been found to have potent anti-HIV activity. The compounds of the present invention have the following formulae: or pharmaceutically acceptable salts thereof, wherein R1 is a C2-C20 substituted or unsubstituted carboxyacyl, R2 is a C2-C20 substituted or unsubstituted carboxyacyl; and R3 is hydrogen, halogen, amino, optionally substituted mono- or di-alkylamino, or —OR4, where R4 is hydrogen, C1-4 alkanoyl, benzoyl, or C2-C20 substituted or unsubstituted carboxyacyl; wherein the dashed line represents an optional double bond between C20 and C29.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: January 9, 2001
    Assignees: The University of North Carolina at Chapel Hill, BBI Biotech Research Laboratories, Inc.
    Inventors: Kuo-Hsiung Lee, I-Chen Sun, Hui-Kang Wang, Louis Mark Cosentino