Abstract: A biochip for measuring a cell density of target bio-particles in a sample is provided. The biochip includes a spiral electrode pair and a concentric electrode array. The spiral electrode pair includes a first spiral electrode and a second spiral electrode that are parallel to each other and that are spaced apart from each other. Each of the first spiral electrode and the second spiral electrode is shaped in a spiral extending in one of clockwise and counterclockwise directions. The concentric electrode array includes a plurality of arcs that are concentric and extend in a circular direction around the spiral electrode pair.

Abstract: A microfluidic particle sorter includes a chip body and at least one sorting unit provided inside the chip body and including a microfluidic channel and at least one first DLD array. The microfluidic channel extends along a length direction, has an inlet and an outlet, and has a first side and a second side. The at least one first DLD array includes first DLD columns arranged along the length direction. The first DLD columns, from the inlet toward the outlet, are gradually shifted toward the second side such that two adjacent ones of the first DLD columns are offset from each other by a predetermined distance. Each of the first DLD columns has first split pillars. Each of the first split pillars has a first upstream side and a first downstream side, and includes two first parts that are spaced apart from each other to define a first micro-gap.

Abstract: In the present disclosure, A cold waterway, a hot waterway and a mixing waterway and a main body are formed integrally in a valve structure, and a faucet structure has the valve structure, a valve core and a handle cover. The cold waterway, the hot waterway and the mixing waterway are formed in the main body by drilling the main body, such that the above three waterways and the main body are formed integrally. Then, an outlet is disposed to be connected to an annular waterway surrounding the main body, and the annular waterway outputs water to the outlet. Thus, it effectively solves the problems of water seepage caused by the tolerance between components or the long-term use of the valve core, and achieves the main advantages of effectively saving water by avoiding water seepage, and eliminating the need for gaskets to avoid poor sealing after aging.

Abstract: In the present disclosure, a cold waterway, a hot waterway and a mixing waterway and a main body are formed integrally in a valve structure, and a faucet structure has the valve structure, a valve core and a handle cover. The cold waterway, the hot waterway and the mixing waterway are formed in the main body by drilling the main body, such that the above three waterways and the main body are formed integrally. Then, an outlet is disposed to be connected to an annular waterway surrounding the main body, and the annular waterway outputs water to the outlet. Thus, it effectively solves the problems of water seepage caused by the tolerance between components or the long-term use of the valve core, and achieves the main advantages of effectively saving water by avoiding water seepage, and eliminating the need for gaskets to avoid poor sealing after aging.

Abstract: A photoelectrical device for detection of bacterial cell density includes a substrate, a driving electrode layer, an AC power source and a photoelectric conversion layer. The driving electrode layer is disposed on the substrate and includes a central electrode and a peripheral electrode pattern surrounding the central electrode. A fluid sample is disposed on the driving electrode layer. The AC power source is electrically connected to the driving electrode layer, and used to produce a non-uniform alternating electric field in the fluid sample on the driving electrode layer for driving the target bioparticles to gather up on the central electrode to form a particle cluster. The photoelectric conversion layer is used for receiving a light detecting beam after passing through the particle cluster and outputting an electric current based on the optical density of light detecting beam. The electric current changes as a concentration of the target bioparticles changes.

Abstract: A photoelectrical device for detection of bacterial cell density includes a substrate, a driving electrode layer, an AC power source and a photoelectric conversion layer. The driving electrode layer is disposed on the substrate and includes a central electrode and a peripheral electrode pattern surrounding the central electrode. A fluid sample is disposed on the driving electrode layer. The AC power source is electrically connected to the driving electrode layer, and used to produce a non-uniform alternating electric field in the fluid sample on the driving electrode layer for driving the target bioparticles to gather up on the central electrode to form a particle cluster. The photoelectric conversion layer is used for receiving a light detecting beam after passing through the particle cluster and outputting an electric current based on the optical density of light detecting beam. The electric current changes as a concentration of the target bioparticles changes.

Abstract: A bio-chip adapted for separating and concentrating particles in a solution includes a chip body defining a receiving space therein for receiving the solution, an inner electrode disposed in the receiving space, an outer electrode unit disposed in the receiving space of the chip body and including a first outer electrode that is spaced apart from and surrounds the inner electrode, and a second outer electrode that is spaced apart from and surrounds the first outer electrode, and a power source electrically connected to the inner electrode, the first outer electrode, and the second outer electrode. A method for using the bio-chip to separating and concentrating the particles in the solution is also disclosed in the present invention.

Abstract: A method of antibiotic susceptibility testing is disclosed, and includes the following steps: (A) providing a sample to be tested wherein the sample contains a microbe; (B) adding an antibiotic into the sample, wherein the antibiotic serves to inhibit cell wall synthesis; (C) checking the sample by dielectrophoresis and observing a shape change of the microbe; and (D) determining whether the microbe is susceptible to the antibiotic according to the shape change thereof. The present invention also discloses a method for determining a minimum inhibitory concentration of the antibiotic.

Abstract: A method of microbial identification is disclosed. The method includes the steps of assembling dielectrophoretic particles modified with specific DNA probes on a surface thereof in a continuous fluid at a predetermined location in a microchannel to form a particle assembly by a negative dielectrophoretic force and a hydrodynamic force provided by the continuous fluid, narrowing gaps between the dielectrophoretic particles of the particle assembly to enhance the electric field in the gaps between the dielectrophoretic particles, injecting a fluid containing target DNAs of a target microbe into the microchannel at a predetermined flow rate to move the target DNAs toward the particle assembly and generating a positive dielectrophoretic force by the enhanced electric field to attract the target DNAs toward the dielectrophoretic particles of the particle assembly for hybridization with the DNA probes. The present invention also discloses a method of manipulation of nanoscale biomolecules.

Abstract: A bio-chip adapted for separating and concentrating particles in a solution includes a chip body defining a receiving space therein for receiving the solution, an inner electrode disposed in the receiving space, an outer electrode unit disposed in the receiving space of the chip body and including a first outer electrode that is spaced apart from and surrounds the inner electrode, and a second outer electrode that is spaced apart from and surrounds the first outer electrode, and a power source electrically connected to the inner electrode, the first outer electrode, and the second outer electrode. A method for using the bio-chip to separating and concentrating the particles in the solution is also disclosed in the present invention.

Abstract: A method of antibiotic susceptibility testing is disclosed, and includes the following steps: (A) providing a sample to be tested wherein the sample contains a microbe; (B) adding an antibiotic into the sample, wherein the antibiotic serves to inhibit cell wall synthesis; (C) checking the sample by dielectrophoresis and observing a shape change of the microbe; and (D) determining whether the microbe is susceptible to the antibiotic according to the shape change thereof. The present invention also discloses a method for determining a minimum inhibitory concentration of the antibiotic.

Abstract: A method of microbial identification is disclosed. The method includes the steps of assembling dielectrophoretic particles modified with specific DNA probes on a surface thereof in a continuous fluid at a predetermined location in a microchannel to form a particle assembly by a negative dielectrophoretic force and a hydrodynamic force provided by the continuous fluid, narrowing gaps between the dielectrophoretic particles of the particle assembly to enhance the electric field in the gaps between the dielectrophoretic particles, injecting a fluid containing target DNAs of a target microbe into the microchannel at a predetermined flow rate to move the target DNAs toward the particle assembly and generating a positive dielectrophoretic force by the enhanced electric field to attract the target DNAs toward the dielectrophoretic particles of the particle assembly for hybridization with the DNA probes. The present invention also discloses a method of manipulation of nanoscale biomolecules.