Patents by Inventor I-HSIN YEH

I-HSIN YEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cas9 plasmid, genome editing system and method of
    Patent number: 9988637
    Abstract: A Cas9 expression plasmid, a genome editing system and a genome editing method for Escherichia coli are provided. The Cas9 expression plasmid includes a tracrRNA sequence, a Cas9 gene and a chloramphenicol resistance gene (CmR). The Cas9 expression plasmid is applied to CRISPR/Cas-coupled ?-red recombineering system for editing genomes of E. coli with high efficiency.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: June 5, 2018
    Assignees: NATIONAL TSING HUA UNIVERISTY, CHANG CHUN PLASTICS CO., LTD, CHANG CHUN PETROCHEMICAL CO., LTD
    Inventors: Yu Chen Hu, Mu-En Chung, I-Hsin Yeh, Hung Li, Li-Yu Sung
  • CAS9 PLASMID, GENOME EDITING SYSTEM AND METHOD OF ESCHERICHIA COLI
    Publication number: 20170226522
    Abstract: A Cas9 expression plasmid, a genome editing system and a genome editing method for Escherichia coli are provided. The Cas9 expression plasmid includes a tracrRNA sequence, a Cas9 gene and a chloramphenicol resistance gene (CmR). The Cas9 expression plasmid is applied to CRISPR/Cas-coulped ?-red recombineering system for editing genomes of E. coli with high efficiency.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Inventors: YU CHEN HU, MU-EN CHUNG, I-HSIN YEH, HUNG LI, LI-YU SUNG
  • METHOD FOR BACTERIAL GENOME EDITING
    Publication number: 20170114367
    Abstract: A method for bacterial genome editing includes: providing a bacterial cell; transforming a pCas9 plasmid and a pKD46 plasmid into the bacterial cell; co-transforming a pCRISPR::LacZ plasmid and an exogenous DNA into the bacterial cell carrying the pCas9 plasmid and the pKD46 plasmid, so as to obtain a strain broth; and spreading the strain broth on a culture medium to conduct cultivation.
    Type: Application
    Filed: March 10, 2016
    Publication date: April 27, 2017
    Inventors: YU CHEN HU, MU-EN CHUNG, I-HSIN YEH, HUNG LI