Abstract: A micro-fluidic electronic device includes a micro-fluidic component and an electronic component formed on a sheet of paper. An electrically-active layer of the electronic component, such as a nano-material layer, interacts with a fluid sample deposited within a fluid reservoir of the component, and changes the electronic properties of the electronic component. This can be detected by passing an electrical signal through the electronic component. The micro-fluidic electronic device can be formed straightforwardly and inexpensively by printing or mold-casting.

Abstract: The invention relates to a method for detecting the presence or amount of an analyte, said method comprising (a) coupling the analyte to a carrier molecule, wherein the carrier molecule is larger in size, electrically charged and/or polar, to form an analyte:carrier molecule complex; (b) contacting the analyte:carrier molecule complex of (a) with an analyte-binding molecule coupled to a semiconducting nanostructure; and (c) determining the change in conductance upon binding of the analyte:carrier molecule complex to the analyte-binding molecule and correlating the determined change in conductance to the presence or amount of the analyte. Alternatively, the analyte:carrier molecule complex of (a) is immobilized on the nanostructure and the immobilized analyte:carrier molecule complex is contacted with the analyte-binding molecule.