Patents by Inventor I-Ying Kuo

I-Ying Kuo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody Binding to CHI3L1 for Treating Cancer
    Publication number: 20240400717
    Abstract: An antibody or an antigen-binding portion thereof binding to CHI3L1 includes a heavy chain variable region and a light chain variable region. The antibody or the antigen-binding portion thereof targeting CHI3L1 not just inhibit activated AKT and ERK signals, cancer cells migration, tumor progression, tumor fibrosis, angiogenesis and cancer-induced muscle loss such as cachexia, but modulate TME toward an immunostimulatory phenotype.
    Type: Application
    Filed: September 30, 2022
    Publication date: December 5, 2024
    Inventors: Yi-Ching Wang, Chih-Peng Chang, Pei-Chia Su, I-Ying Kuo, Jhong-Jhe You, Jeng-Horng Her