Patents by Inventor Iain Alasdair Russell

Iain Alasdair Russell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EDITING TO IMPROVE JOINT FUNCTION
    Publication number: 20230257779
    Abstract: The present disclosure provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: July 16, 2021
    Publication date: August 17, 2023
    Applicant: Orthobio Therapeutics, Inc.
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen, George Gentsch
  • GENE EDITING TO IMPROVE JOINT FUNCTION
    Publication number: 20230235321
    Abstract: The present disclosure provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: July 18, 2022
    Publication date: July 27, 2023
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen, George Gentsch
  • Optimised Methods for Cleavage of Target Sequences
    Publication number: 20230167443
    Abstract: The invention provides methods of selecting guide RNA sequences, and the use of such sequences in CRISPR-Cas gene editing of a target sequence. In particular, the invention relates to a method of selecting guide RNA sequences, based on the determined frequencies of editing outcomes, which in one case result in low mosaicism and in another case result in large deletions or knockouts.
    Type: Application
    Filed: March 16, 2021
    Publication date: June 1, 2023
    Inventor: Iain Alasdair RUSSELL
  • Gene Editing to Improve Joint Function
    Publication number: 20220265851
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: May 9, 2022
    Publication date: August 25, 2022
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen
  • Gene editing to improve joint function
    Patent number: 11324838
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: May 10, 2022
    Assignee: ORTHOBIO THERAPEUTICS, INC.
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen
  • Gene Editing to Improve Joint Function
    Publication number: 20210261956
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 26, 2021
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen
  • Gene Editing to Improve Joint Function
    Publication number: 20210252082
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: February 3, 2021
    Publication date: August 19, 2021
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen
  • Gene editing to improve joint function
    Patent number: 11033590
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: June 15, 2021
    Assignee: ORTHOBIO THERAPEUTICS, INC.
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen
  • Gene Editing to Impove Joint Function
    Publication number: 20200360454
    Abstract: The present invention provides compositions and methods for treating joint disorders that are characterized by an inflammatory component. In some aspects, the compositions and methods are to prevent the progression of osteoarthritis and other arthritides and to treat osteoarthritis and other arthritides in a mammalian joint.
    Type: Application
    Filed: June 29, 2020
    Publication date: November 19, 2020
    Inventors: Peter J. Millett, Iain Alasdair Russell, Matthew J. Allen