Patents by Inventor Iain F. Pickersgill

Iain F. Pickersgill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for preparing 2-alkynyladenosine derivatives
    Patent number: 7671191
    Abstract: Disclosed are methods for preparing 2-alkynyladenosine derivatives of formula A: or a stereoisomer, pharmaceutically acceptable salt, hydrate, solvate, acid salt hydrate or isomorphic crystalline form thereof, the method comprising the step of: contacting 2-iodoadenosine-5?-N-ethyluronamide with a compound of formula B: wherein Z is —C(?O)OR or —CH2C(?O)R, where R is a C1 to C5 alkyl, preferably The methods are useful for preparing 2-alkynyladenosine derivatives that are, in certain embodiments, adenosine receptor agonists.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: March 2, 2010
    Assignee: PGx Health, LLC
    Inventors: Iain F. Pickersgill, Edward H. Cheesman
  • Methods for preparing 2-alkynyladenosine deriviatives
    Publication number: 20080177055
    Abstract: Disclosed are methods for preparing 2-alkynyladenosine derivatives of formula A: or a stereoisomer, pharmaceutically acceptable salt, hydrate, solvate, acid salt hydrate or isomorphic crystalline form thereof, the method comprising the step of: contacting 2-iodoadenosine-5?-N-ethyluronamide with a compound of formula B: wherein Z is —C(?O)OR or —CH2C(?O)R, where R is a C1 to C5 alkyl, preferably The methods are useful for preparing 2-alkynyladenosine derivatives that are, in certain embodiments, adenosine receptor agonists.
    Type: Application
    Filed: October 17, 2007
    Publication date: July 24, 2008
    Inventors: Iain F. Pickersgill, Edward H. Cheesman