Abstract: A medicament delivery device for dispensing discrete doses of medicament comprises: first and second medicament carriers each comprising said doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer; first and second opening mechanisms each arranged to handle a respective one of the first and second medicament carriers and to open each compartment of the respective medicament carrier by separating the sealing layer from the carrier strip as the medicament carrier is advanced through the device; a take-up spool arranged to wind the separated sealing layers thereon such as to maintain the separated sealing layers in tension, each separated sealing layer having a path of travel between a respective one of the first and second opening mechanisms and the take-up spool; and a tension control element in contact with each of the separated sealing layers, wherein at least a part of the tension control element is arranged to be movable by a biasi

Abstract: A manifold for a medicament delivery device configured to deliver discrete doses of medicament contained in a plurality of individual compartments spaced along a carrier strip and sealed by a sealing layer to form a medicament carrier, the manifold comprising: at least one opening mechanism comprising a release member arranged to engage between the carrier strip and the sealing layer of a medicament carrier so as to separate the sealing layer from the carrier strip and thereby open a compartment of the medicament carrier as it is advanced into an entrainment position; wherein the release member includes a surface configured to cover the opened compartment when in the entrainment position so as substantially to contain the medicament dose of said opened compartment.

Abstract: A device for releasing discrete doses of medicament carried in a plurality of spaced-apart compartments on a medicament carrier, each compartment being arranged in a carrier strip and sealed by a sealing layer, the device comprising: a release mechanism arranged to engage between the carrier strip and the sealing layer so as to unseal at least a portion of the compartment and expose the medicament dose contained therein, wherein the release mechanism preferably covers said exposed compartment in place of the sealing layer.

Abstract: An inhaler comprising a reservoir of an inhalable composition. A valve element moved by a flexible diaphragm and biased into a position in which it closes a composition flow path from a reservoir. A first air flow path is partly defined by one side of the diaphragm and a second air flow path is partly defined by the opposite side of the diaphragm. Each flow path has an outlet opening at an outlet end and the second flow path has an inlet upstream of the outlet end. The air flow paths are arranged such that suction at the outlet end causes a reduction in pressure in the first air flow path relative to the pressure in the second air flow path creating a pressure differential across the diaphragm that moves the valve element against the biasing force to open the composition flow path.

Abstract: An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.

Abstract: A combination of an inhaler and a refill pack. The inhaler comprises a reservoir for an inhalable composition, a heating element and/or vibrating transducer to selectively volatilise at least some components of the composition and at least one inhaler capacitor arranged to supply electrical power to the heater and/or vibrating transducer when a user inhales from the inhaler. The refill pack comprises a refill reservoir of inhalable composition and a battery coupled to a refill capacitor, and is arranged to engage with the inhaler and to simultaneously refill the reservoir and recharge the inhaler capacitor from the refill capacitor. The invention also extends to the inhaler and refill pack separately and to a method of refilling and recharging the inhaler.

Abstract: An inhaler comprising a reservoir of an inhalable composition. A housing contains the reservoir and has an outlet end and an opposite end. A composition flow path for the flow of the composition extends from the reservoir along the flow path and out of a composition outlet at the outlet end of the housing. A flexible diaphragm within the housing defines an air flow path from an air inlet to an air outlet at the outlet end of the housing, the diaphragm extending past the air flow inlet towards the opposite end separating the air flow path on one side of the diaphragm from the remainder of the housing on the opposite side of the diaphragm.

Abstract: There is disclosed a liquid formulation for inhalation into the lungs, comprising an aqueous solution of nicotine or a nicotine analogous molecule, at least one organic and/or inorganic salt, an organic liquid having a viscosity higher than water, and optionally an organic alcohol, wherein the pH of the formulation is greater than pH 7 and the formulation does not include a propellant. There is further disclosed a corresponding method of aerosolising the liquid formulation, a method for delivering nicotine to the user, and an aerosol-generating device.

Abstract: An inhaler comprising a reservoir of an inhalable composition, a heater to selectably volatilize at least some components of the composition, and a power source arranged to selectively supply electrical power to the heater when the user inhales from the inhaler. The power source is arranged to heat the heater to a temperature that will volatilize some, but not all of the components of the composition.

Abstract: An inhaler comprising a reservoir of an inhalable composition, a heater to selectably volatilise at least some components of the composition, and a power source arranged to selectively supply electrical power to the heater when the user inhales from the inhaler. The power source is arranged to heat the heater to a temperature that will volatilise some, but not all of the components of the composition.

Abstract: An inhaler comprising a reservoir for an inhalable composition and a heating element and/or vibrating transducer to selectively volatilise at least some components of the composition. A power source supplies electrical power to the heater/transducer when the user inhales from the inhaler. The inhaler further comprises at least one airflow path arranged to draw air in through the inhaler as a user inhales from an inhaling end, and impinge on a plume of composition downstream of the heater/transducer at the inhaling end to reduce the mean particle size of the plume.

Abstract: A combination of an inhaler and a refill pack. The inhaler comprises a reservoir for an inhalable composition, a heating element and/or vibrating transducer to selectively volatilise at least some components of the composition and at least one inhaler capacitor arranged to supply electrical power to the heater and/or vibrating transducer when a user inhales from the inhaler. The refill pack comprises a refill reservoir of inhalable composition and a battery coupled to a refill capacitor, and is arranged to engage with the inhaler and to simultaneously refill the reservoir and recharge the inhaler capacitor from the refill capacitor. The invention also extends to the inhaler and refill pack separately and to a method of refilling and recharging the inhaler.

Abstract: An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.

Abstract: An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.

Abstract: Container assembly comprising a container and a top chime fixed to each other, the container having a top part and a peripheral side wall, characterized in that the fixation between the chime and the container is situated at the top part of the container and at a distance from said peripheral side wall.

Abstract: An inhaler comprising a reservoir of an inhalable composition. A valve element moved by a flexible diaphragm and biased into a position in which it closes a composition flow path from a reservoir. A first air flow path is partly defined by one side of the diaphragm and a second air flow path is partly defined by the opposite side of the diaphragm. Each flow path has an outlet opening at an outlet end and the second flow path has an inlet upstream of the outlet end. The air flow paths are arranged such that suction at the outlet end causes a reduction in pressure in the first air flow path relative to the pressure in the second air flow path creating a pressure differential across the diaphragm that moves the valve element against the biasing force to open the composition flow path.

Abstract: A simulated cigarette device containing a pressurised reservoir of inhalable composition and an outlet valve controlling the output of the inhalable composition. A capillary plug extends from the vicinity of the outlet to fill a substantial portion of the reservoir and is configured to wick the inhalable composition towards the outlet valve.

Abstract: A diaphragm for use in a valve assembly, comprising at least one sealing portion and a fixation portion, characterized in that the fixation portion and the at least one sealing portion are connected by a flexible portion.

Abstract: An inhaler comprising a reservoir of an inhalable composition with an outlet at one end through which the inhalable composition is discharged. A non-metered breath-activated valve is provided between the one end and the reservoir, the breath-activated valve comprising a flow path extending from the reservoir to the outlet end. At least a portion of the flow path is a deformable tube. A clamping member pinches the deformable tube closed when no suction force is applied to the device and releases the tube to open the flow path when suction is applied at the outlet, to provide uninterrupted flow from the reservoir to the outlet.

Abstract: An inhaler comprising a reservoir of an inhalable composition. A housing contains the reservoir and has an outlet end and an opposite end. A composition flow path for the flow of the composition extends from the reservoir along the flow path and out of a composition outlet at the outlet end of the housing. A flexible diaphragm within the housing defines an air flow path from an air inlet to an air outlet at the outlet end of the housing, the diaphragm extending past the air flow inlet towards the opposite end separating the air flow path on one side of the diaphragm from the remainder of the housing on the opposite side of the diaphragm.