Abstract: The present invention provides methods for treating or preventing aggression, agitation, irritability and/or anger in a subject comprising administrating to a subject in need thereof a therapeutically effective amount of a compound of Formula (I).

Abstract: An integrated circuit (IC) chip includes system circuitry having system memory, and a master processor and a checker processor configured to operate in lockstep; and monitoring circuitry comprising an internal lockstep monitor, a master tracer and a checker tracer. The internal lockstep monitor is configured to: observe states of internal signals of the master processor and the checker processor, compare corresponding observed states of the master processor and the checker processor, and if the corresponding observed states differ: trigger the master tracer to output stored master trace data recorded from the output of the master processor, and trigger the checker tracer to output stored checker trace data recorded from the output of the checker processor.

Abstract: Disclosed herein are compounds, compositions and methods for the treatment of neurological, psychiatric disorders which are characterized by a fundamental disruption of social behaviour, and substance use disorders. In particular, disclosed herein are compounds of Formula (I), or salts or prodrugs thereof. Methods of treating or preventing neurological, psychiatric disorders and substance use disorders, using compounds of Formula (I), or salts and prodrugs are also disclosed.

Abstract: Disclosed herein are compounds according to Formula I; a pharmaceutical composition including, consisting essentially of, or consisting of: a pharmaceutically acceptable compound of Formula I and a pharmaceutically acceptable carrier, diluent, or excipient; the use of compounds of Formula I in the preparation of a medicament; and a method including administering a pharmaceutical compositions comprising the compound of Formula I to a patient. The compounds, compositions, use, and methods are directed to the treatment of neurological, psychiatric disorders which are characterised by a fundamental disruption of social behaviour, and substance use disorders.

Abstract: Disclosed herein are compounds, compositions and methods for the treatment of neurological, psychiatric disorders which are characterized by a fundamental disruption of social behaviour, and substance use disorders. In particular, disclosed herein are compounds of Formula (I), or salts or prodrugs thereof. Methods of treating or preventing neurological, psychiatric disorders and substance use disorders, using compounds of Formula (I), or salts and prodrugs are also disclosed.

Abstract: This invention relates to methods of treating, preventing, managing and/or controlling opioid withdrawal and/or a symptom associated with the opioid withdrawal. Compounds, compositions, medicaments and kits are provided that may be used in these methods.

Abstract: Disclosed herein are methods for causing weight loss, for managing weight, and for suppressing an appetite for food in a subject, and methods for reducing the consumption of food by a subject by administering the compounds, or pharmaceutically acceptable salts or prodrugs thereof, of the invention.

Abstract: Disclosed herein are compounds, compositions and methods for the treatment of neurological, psychiatric disorders which are characterised by a fundamental disruption of social behaviour, and substance use disorders. In particular, disclosed herein are compounds of Formula (I), or salts or prodrugs thereof. Methods of treating or preventing neurological, psychiatric disorders and substance use disorders, using compounds of Formula (I), or salts and prodrugs are also disclosed.

Abstract: Disclosed herein are compounds, compositions and methods for the treatment of neurological, psychiatric disorders which are characterised by a fundamental disruption of social behaviour, and substance use disorders. In particular, disclosed herein are compounds of Formula (I), or salts or prodrugs thereof. Methods of treating or preventing neurological, psychiatric disorders and substance use disorders, using compounds of Formula (I), or salts and prodrugs are also disclosed.

Abstract: The present invention provides methods for the therapy and prevention of problem drinking in alcohol-dependent and non-dependent subjects and those at risk of developing problem drinking behavior, and compositions of matter comprising oxytocin or an analog or derivative thereof or an agonist or partial agonist of an oxytocin receptor that are useful in preventing or treating problem drinking.

Abstract: The present invention provides methods for the therapy and prevention of problem drinking in alcohol-dependent and non-dependent subjects and those at risk of developing problem drinking behavior, and compositions of matter comprising oxytocin or an analog or derivative thereof or an agonist or partial agonist of an oxytocin receptor that are useful in preventing or treating problem drinking.

Abstract: The present invention provides methods for the therapy and prevention of problem drinking in alcohol-dependent and non-dependent subjects and those at risk of developing problem drinking behavior, and compositions of matter comprising oxytocin or an analog or derivative thereof or an agonist or partial agonist of an oxytocin receptor that are useful in preventing or treating problem drinking.

Abstract: The invention provides a method for the removal of contaminating materials from pipework, the contaminating materials comprising deposits on the pipework which cause a reduction in the effective internal diameter of the pipes and thereby effect a reduction in the rate of flow of a fluid through the pipework, the method comprising treating the contaminating materials with at least one carbamate salt. The methods is also suitable for the treatment of contaminating materials which have a particularly deleterious effect on fluid flow and comprise partial or total blockages of the pipework. The carbamate is preferably in the form of an aqueous solution, and a preferred carbamate salt is ammonium carbamate. The treatment may be carried out in the presence of an additive such as caesium carbonate or ammonium bicarbonate. Optionally the treatment may be accompanied by a pre-treatment or post-treatment with aid, this being followed by a water wash.

Abstract: There is disclosed an oral cleansing product comprising as an abrasive an alumnina in the form of particles having d10 below 3.5 &mgr;m, d50 below 1.0 &mgr;m, and a specific surface area below 6 m2/g.

Abstract: There is disclosed a toothpaste comprising as an abrasive an alumina in the form of particles having d10 below 3.5 &mgr;m, d50 below 1.0 &mgr;m and a specific surface area below 6 m2/g.

Abstract: A spent fuel reprocessing method includes at least the formation of an aqueous solution and at least one solvent extraction step. Formohydroxarmic acid is used to reduce any Np(VI) to Np(V) and/or to form a complex with Np(IV). As a result, substantially all the neptunium present is retained in the aqueous phase during solvent extraction.

Abstract: An apparatus for removing cigarettes from a package. The apparatus has at least one cutter for cutting open the package with a full cut at right angles to the lengthwise orientation of the cigarettes. The apparatus has a separating station in which the cigarettes are removed from the cut-open package prior to further processing. The separating station has two vertically oriented spaced-apart deformation faces that extend parallel to one another and are rotatable for pivoting the package out of an essentially horizontal position and into an inclined to even vertical position. The distance between the deformation faces is less than the width of the package as measured between its two narrow long sides via which the package rests against the deformation faces during the pivoting process.

Abstract: A method and apparatus for recovering tobacco from imperfect cigarettes that are ejected downstream of a cigarette-producing machine and are supplied to a recovery apparatus for opening the paper casings and separating the tobacco from the paper pieces and any filters that are present. The imperfect cigarettes of a given cigarette-producing machine are continuously supplied to an in-line recovery apparatus, which has a space-saving configuration, is coordinated to the output of the cigarette-producing machine, and is mounted adjacent thereto. Varying quantities of imperfect cigarettes are collected within the recovery apparatus, which is equipped with a rotary conveyer. A uniform stream of the recovered tobacco is returned to the cigarette-producing machine.