Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by utilizing a stabilizing structure that preferentially contracts to provide for movement of the tissue. Some embodiments may utilize a protective layer, such as a mesh or net layer, attached to a top surface of the stabilizing structure. The protective layer prevents a drape positioned over the stabilizing structure from being drawn into cells of the stabilizing structure, and permits visualization of the collapse of the cells.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by utilizing a stabilizing structure that preferentially contracts to provide for movement of the tissue. Some embodiments may utilize a protective layer, such as a mesh or net layer, attached to a top surface of the stabilizing structure. The protective layer prevents a drape positioned over the stabilizing structure from being drawn into cells of the stabilizing structure, and permits visualization of the collapse of the cells.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: Disclosed embodiments relate to a wound therapy system that can deliver nitric oxide and apply negative pressure to a wound. The wound therapy system can include a wound dressing for placement over the wound, a source of negative pressure connected to the wound dressing, a source of nitric oxide connected to the wound dressing, and a controller configured to regulate nitric oxide delivery and negative pressure application to the wound dressing. The controller can be programmed to deliver various concentrations of nitric oxide to the wound dressing at various times over the course of treatment of the wound. The controller can also be programmed to apply various levels of negative pressure to the wound dressing at various times over the course of treatment of the wound.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may include wound closure devices built from smaller units that are modular, assemble-able and/or customizable.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may include wound closure devices built from smaller units that are modular, assemble-able and/or customizable.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by utilizing a stabilizing structure that preferentially contracts to provide for movement of the tissue. Some embodiments may utilize a protective layer, such as a mesh or net layer, attached to a top surface of the stabilizing structure. The protective layer prevents a drape positioned over the stabilizing structure from being drawn into cells of the stabilizing structure, and permits visualization of the collapse of the cells.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may include wound closure devices built from smaller units that are modular, assemble-able and/or customizable.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The activator layer may include a copolymer of monomers with one or more covalently linked multifunctional groups.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The nitric oxide source layer may include a nitrite salt. Nitrite ions of the nitric oxide source layer may react with the acidic groups of the activating layer to generate nitric oxide. The activating layer may include a window at the center, and a central absorbent material may be positioned at the window. Various separating layers may also be incorporated into the dressing to control the interaction between activating layer and nitric oxide source layer.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing comprises a cover layer, an acid providing layer and a nitrite providing layer. The acid providing layer comprises acidic groups and may be hydrogel or Xerogel. The nitrite providing layer comprises a nitrite salt. The wound dressing may also include other layers, one or more acquisition distribution layers or masking layers. The masking layers can at least partially prevent visualization of the layer below the masking layer. Nitrite ions of the nitrite providing layer may react with the acidic groups of the acid providing layer to generate nitric oxide. The acid providing layer further includes one or more material layers to reduce the adhesiveness of the acid providing layer. The acid providing layer can also include perforations.

Abstract: A negative pressure wound closure devices, systems and methods. Embodiments of the invention facilitate closure of the wound by preferentially contracting under negative pressure to provide for movement of the surrounding tissues. Some embodiments may utilize a stabilizing structure with a plurality of cells configured to collapses more in the x-direction than in the y-direction.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Some embodiments may include wound closure devices built from smaller units that are modular, assemble-able and/or customizable.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by utilizing a stabilizing structure that preferentially contracts to provide for movement of the tissue. Some embodiments may utilize a protective layer, such as a mesh or net layer, attached to a top surface of the stabilizing structure. The protective layer prevents a drape positioned over the stabilizing structure from being drawn into cells of the stabilizing structure, and permits visualization of the collapse of the cells.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment. In certain embodiments, a wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound. The wound dressing further includes a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer and configured to transmit wound fluid away from the wound, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. The apparatus also includes an oxygen source configured to supply oxygen to the wound through the orifice.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Abstract: A negative pressure wound closure system and methods for using such a system are described. Preferred embodiments of the invention facilitate closure of the wound by utilizing a stabilizing structure that preferentially contracts to provide for movement of the tissue. Some embodiments may utilize a protective layer, such as a mesh or net layer, attached to a top surface of the stabilizing structure. The protective layer prevents a drape positioned over the stabilizing structure from being drawn into cells of the stabilizing structure, and permits visualization of the collapse of the cells.