Patents by Inventor Iakov Iurevich USTIUGOV

Iakov Iurevich USTIUGOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Trispecific antibodies against IL-17A, IL-17F and other pro-inflammatory molecule
    Patent number: 11453717
    Abstract: The present invention relates to the field of biotechnology and provides monoclonal tri-specific binding molecules that specifically bind to human IL-17A, human IL-17F, and a human pro-inflammatory molecule (in particular, TNF?) with high affinity. The invention also relates to DNA constructs encoding said binding molecules, related expression vectors and methods of production, and methods of treatment using said binding molecules.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 27, 2022
    Inventors: Dmitry Valentinovich Morozov, Andrei Borisovich Ulitin, Ekaterina Sergeevna Zubareva, Iakov Iurevich Ustiugov, Aleksandr Vladimirovich Karabelskii, Dmitry Valeryevich Korzhavin, Tatiana Veniaminovna Chernovskaya, Aleksandr Valerevich Grachev, Yury Ivanovich Basovskiy, Ekaterina Aleksandrovna Lomkova, Veronika Sergeevna Usatova, Aleksei Aleksandrovich Aleksandrov, Elena Leonidovna Morozova, Roman Alekseevich Ivanov, Pavel Andreevich Iakovlev
  • MONOCLONAL ANTIBODY THAT BINDS SPECIFICALLY TO GITR
    Publication number: 20220213209
    Abstract: The present invention relates to biotechnology, in particular to antibodies or antigen-binding fragments thereof, and to use thereof. More particularly, the present invention relates to monoclonal antibodies that specifically bind to GITR. The invention also relates to a nucleic acid encoding said antibody or antigen-binding fragment thereof, an expression vector, a method for preparing said antibody, and use of said antibody in treatment of diseases or disorders associated with GITR.
    Type: Application
    Filed: April 23, 2020
    Publication date: July 7, 2022
    Inventors: Andrei Borisovich ULITIN, Olesya Nikolaevna KOZLOVA, Aleksandr Andreevich GORDEEV, Ksenia Mihailovna BURNYSHEVA, Anastasia Nikolaevna ISHUTINOVA, Aleksandra Aleksandrovna SOZONOVA, Sergei Andreevich AGEEV, Aleksandr Nikolaevich DORONIN, Vladimir Sergeevich TSYMPILOV, Ivan Vladimirovich MITROSHIN, Valery Vladimirovich SOLOVYEV, Iakov Iurevich USTIUGOV, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV
  • MONOCLONAL ANTIBODY THAT SPECIFICALLY BINDS TO CD20
    Publication number: 20220089761
    Abstract: The present invention relates to biotechnology and provides a monoclonal antibody that specifically binds to CD20. The invention also relates to DNA encoding said antibody, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibody.
    Type: Application
    Filed: October 30, 2019
    Publication date: March 24, 2022
    Inventors: Pavel Andreevich IAKOVLEV, Natalia Eugenievna PESTOVA, Arina Vitalevna ANIKINA, Anna Alexandrovna TRUDOVISHNIKOVA, Mariia Aleksandrovna SHCHEMELEVA, Nina Grachyaevna KHARATIAN, Valery Vladimirovich SOLOVYEV, Alexey Konstantinovich MISORIN, Sergei Vasilyevich DIDUK, Anna Vladimirovna EROSHOVA, Veronika Sergeevna USATOVA, Elena Andreevna KRENDELEVA, Iakov Iurevich USTIUGOV, Aleksei Aleksandrovich ALEKSANDROV, Iana Andreevna SMIRNOVA, Svetlana Vladimirovna KOSKOVA, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV
  • Monoclonal antibody to PD-L1
    Patent number: 11236167
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 1, 2022
    Inventors: Andrei Borisovich Ulitin, Viktoriia Mikhailovna Ekimova, Ekaterina Vladimirovna Sofronova, Yulia Sergeevna Chernykh, Sergei Andreevich Ageev, Anna Konstantinovna Vladimirova, Aleksei Aleksandrovich Aleksandrov, Pavel Alekseevich Grebnev, Valery Vladimirovich Solovyev, Iakov Iurevich Ustiugov, Pavel Andreevich Iakovlev, Timofey Aleksandrovich Nemankin, Dmitry Valentinovich Morozov
  • TRISPECIFIC ANTIBODIES AGAINST IL-17A, IL-17F AND OTHER PRO-INFLAMMATORY MOLECULE
    Publication number: 20210332120
    Abstract: The present invention relates to the field of biotechnology and provides monoclonal tri-specific binding molecules that specifically bind to human IL-17A, human IL-17F, and a human pro-inflammatory molecule (in particular, TNF?) with high affinity. The invention also relates to DNA constructs encoding said binding molecules, related expression vectors and methods of production, and methods of treatment using said binding molecules.
    Type: Application
    Filed: December 2, 2016
    Publication date: October 28, 2021
    Inventors: Dmitry Valentinovich MOROZOV, Andrei Borisovich ULITIN, Ekaterina Sergeevna ZUBAREVA, Iakov Iurevich USTIUGOV, Aleksandr Vladimirovich KARABELSKII, Dmitry Valeryevich KORZHAVIN, Tatiana Veniaminovna CHERNOVSKAYA, Aleksandr Valerevich GRACHEV, Yury Ivanovich BASOVSKIY, Ekaterina Aleksandrovna LOMKOVA, Veronika Sergeevna USATOVA, Aleksei Aleksandrovich ALEKSANDROV, Elena Leonidovna MOROZOVA, Roman Alekseevich IVANOV, Pavel Andreevich IAKOVLEV
  • MONOCLONAL ANTIBODY TO PD-L1
    Publication number: 20200369771
    Abstract: The present invention relates to the field of biotechnology and provides antibodies that specifically binds to PD-L1. The invention also relates to DNA encoding said antibodies, to corresponding expression vectors and to methods of producing, and to methods of treatment using said antibodies.
    Type: Application
    Filed: April 11, 2018
    Publication date: November 26, 2020
    Inventors: Andrey Borisovich ULITIN, Victoria Mikhailovna EKIMOVA, Ekaterina Vladimirovna SOFRONOVA,, Yulia Sergeevna CHERNYKH, Sergei Andreevich AGEEV, Anna Konstantinovna VLADIMIROVA, Aleksei Aleksandrovich ALEKSANDROV, Pavel Alekseevich GREBNEV, Valery Vladimirovich SOLOVYEV, Iakov Iurevich USTIUGOV, Pavel Andreevich IAKOVLEV, Timofey Aleksandrovich NEMANKIN, Dmitry Valentinovich MOROZOV
  • ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME
    Publication number: 20190127478
    Abstract: The present invention relates to biotechnology and comprises isolated monoclonal antibodies, in particular human monoclonal antibodies, which specifically bind to PD-1 with high affinity. The antibodies according to the invention may be chimeric, humanized or human antibodies, or antigen-binding fragments thereof, and may be used as a medicinal agent in oncology and immuno-oncology, for treating diseases associated with various cell proliferation or development disorders. The invention also relates to methods for producing said antibodies and a method for treating human diseases using said antibodies.
    Type: Application
    Filed: July 4, 2017
    Publication date: May 2, 2019
    Inventors: Viktoriia Mikhailovna EKIMOVA, Dmitry Valeryevich KORZHAVIN, Yulia Sergeevna CHERNYKH, Timofey Aleksandrovich NEMANKIN, Valery Vladimirovich SOLOVYEV, Anna Konstantinovna VLADIMIROVA, Irina Andreevna BULANKINA, Sergei Vasilyevich DIDUK, Olga Vladimirovna GONCHAROVA, Anna Vladimirovna EROSHOVA, Iakov Iurevich USTIUGOV, Marina Vladimirovna ARTIUKHOVA, Andrei Borisovich ULITIN, Roman Alekseevich IVANOV, Dmitry Valentinovich MOROZOV