Patents by Inventor Ian A. Cook

Ian A. Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230093826
    Abstract: The present disclosure relates to methods, devices, and systems used for the treatment of and/or promoting recovery from various neurological disorders and conditions, including epilepsy and other seizure disorders and movement and other related disorders, as well as for the treatment of mood, anxiety, post traumatic stress disorder, and cognitive and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 30, 2023
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Christopher DeGiorgio, Ian A. Cook, Alejandro Covalin, Patrick R. Miller, Lara Schrader
  • Publication number: 20220378436
    Abstract: Thin-film mesh for medical devices, including stent and scaffold devices, and related methods are provided. Micropatterned thin-film mesh, such as thin-film Nitinol (TFN) mesh, may be fabricated via sputter deposition on a micropatterned wafer. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh used as a cover for a stent device. The stent device may include two stent modules that may be implanted at a bifurcated aneurysm such that one module passes through a medial surface of the other module. The thin-film mesh may include pores with complex, fractal, or fractal-like shapes. The thin-film mesh may be used as a scaffold for a scaffold device. The thin-film scaffold may be placed in a solution including structural protein such as fibrin, seeded with cells, and placed in the body to replace or repair tissue.
    Type: Application
    Filed: August 1, 2022
    Publication date: December 1, 2022
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta
  • Publication number: 20220331581
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of neurological disorders via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, minimally invasive methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infratrochlear, auriculotermporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal, infraorbital, and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein. Systems and devices configured for therapeutic stimulation of the branches of the trigeminal nerves, such as the superficial trigeminal nerve, and their methods of application are also described.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 20, 2022
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC.
    Inventors: Christopher DeGiorgio, Ian A. Cook, Leon Ekchian
  • Patent number: 11399841
    Abstract: Thin-film mesh for medical devices, including stent and scaffold devices, and related methods are provided. Micropatterned thin-film mesh, such as thin-film Nitinol (TFN) mesh, may be fabricated via sputter deposition on a micropatterned wafer. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh used as a cover for a stent device. The stent device may include two stent modules that may be implanted at a bifurcated aneurysm such that one module passes through a medial surface of the other module. The thin-film mesh may include pores with complex, fractal, or fractal-like shapes. The thin-film mesh may be used as a scaffold for a scaffold device. The thin-film scaffold may be placed in a solution including structural protein such as fibrin, seeded with cells, and placed in the body to replace or repair tissue.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: August 2, 2022
    Assignee: MONARCH BIOSCIENCES, INC.
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta
  • Publication number: 20210251785
    Abstract: A thin-film covered stent device may include a thin-film mesh and a stent backbone covered by the thin-film mesh, thereby forming a dual-layer stent structure. The thin-film covered stent device may have smaller pores and a high pore density compared to conventional stents. For example, the thin-film covered stent device may have a slit length of between 50 and 250 micrometers and a pore density of between 134 and 227 pores per mm2. The thin-film covered stent device facilitates rapid healing of tissue defects such as those encountered during the endovascular treatment of an aneurysm.
    Type: Application
    Filed: April 30, 2021
    Publication date: August 19, 2021
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta
  • Patent number: 11020254
    Abstract: A thin-film covered stent device may include a thin-film mesh and a stent backbone covered by the thin-film mesh, thereby forming a dual-layer stent structure. The thin-film covered stent device may have smaller pores and a high pore density compared to conventional stents. For example, the thin-film covered stent device may have a slit length of between 50 and 250 micrometers and a pore density of between 134 and 227 pores per mm2. The thin-film covered stent device facilitates rapid healing of tissue defects such as those encountered during the endovascular treatment of an aneurysm.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: June 1, 2021
    Assignee: Monarch Biosciences, Inc.
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta
  • Patent number: 10932896
    Abstract: Methods and devices are provided for the use of thin-film cuffs on endovascular grafts. A method includes forming a fenestrated thin-film Nitinol sheet, expanding the fenestrated thin-film Nitinol sheet to expand the fenestrations, and attaching the expanded thin-film Nitinol sheet to a longitudinal end of a cover for an endovascular graft to form a cuff for the endovascular graft. The method may further include implanting the endovascular graft into a blood vessel. An endovascular graft may include a cover having a proximal and distal end, a proximal thin-film mesh cuff extending from the proximal end, and a distal thin-film mesh cuff extending form the distal end.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: March 2, 2021
    Assignee: Monarch Biosciences, Inc.
    Inventors: Ian A. Cook, Colin Kealey, Vikas Gupta
  • Patent number: 10639468
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: May 5, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ian A. Cook, Christopher M. DeGiorgio
  • Patent number: 10537729
    Abstract: Trigeminal nerves are stimulated based upon pulse counting and chronobiology. A cutaneous electrode assembly is applied to the forehead to stimulate the ophthalmic nerves. A method may include determining a number of pulses to be administered to a patient based upon the disorder being treated, and pulsing current through an electrode assembly to stimulate the patient's supraorbital and supratrochlear nerves with the determined number of pulses. Another method may include determining a pulse repetition frequency for pulses to be administered to a patient based upon the disorder being treated, and pulsing current through an electrode assembly to stimulate the patient's supraorbital and supratrochlear nerves at the pulse repetition frequency.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: January 21, 2020
    Assignee: NEUROSIGMA, INC.
    Inventors: Ian A. Cook, Colin Kealey
  • Publication number: 20190269922
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of neurological disorders via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, minimally invasive methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infratrochlear, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal, infraorbital, and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein. Systems and devices configured for therapeutic stimulation of the branches of the trigeminal nerves, such as the superficial trigeminal nerve, and their methods of application are also described.
    Type: Application
    Filed: March 4, 2019
    Publication date: September 5, 2019
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC.
    Inventors: Christopher DeGiorgio, Ian A. Cook, Leon Ekchian
  • Patent number: 10322283
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of mood, anxiety, post traumatic stress disorder, and cognitive and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: June 18, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Christopher DeGiorgio, Ian A. Cook, Alejandro Covalin, Patrick R. Miller, Lara Schrader
  • Patent number: 10238862
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 26, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ian A. Cook, Christopher M. DeGiorgio
  • Patent number: 10195435
    Abstract: The present disclosure relates to methods, devices, and systems used for the treatment of mood, anxiety, cognitive, and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: February 5, 2019
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC.
    Inventors: Christopher M. Degiorgio, Ian A. Cook, Leon Ekchian
  • Publication number: 20180229029
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Application
    Filed: April 10, 2018
    Publication date: August 16, 2018
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ian A. Cook, Christopher M. DeGiorgio
  • Patent number: 10035013
    Abstract: An implantable subcutaneous electrode system is disclosed. The implantable subcutaneous electrode system may include an electrode body with electrical contacts disposed thereon or integrally formed therein. The electrode body also may include an insulation region defined between the electrical contacts and an aperture defined in the electrode body for receiving an anchoring device. A minimally invasive delivery device and methods for delivery of an implantable electrode system is also provided. The methods may include steps of introducing a needle comprising a cannula and a stylet through a patient's skin, removing the stylet while leaving the cannula in place, introducing an electrode applicator through the cannula, the electrode applicator comprising a hollow driver which receives the electrode assembly, and anchoring the electrode assembly to a bone by driving the hollow driver such that a self-tapping screw within the electrode assembly screws into the bone.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: July 31, 2018
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC.
    Inventors: Antonio A. F. Desalles, Alessandra Gorgulho, Christopher M. DeGiorgio, Ian A. Cook, Colin Kealey, Leon Ekchian, Patrick Miller
  • Patent number: 10016601
    Abstract: A system for trigeminal nerve stimulation includes a pulse generator, which includes a user control configured to receive a user adjustment and a microcontroller configured to receive electric stimulation parameters and operate the pulse generator to produce electrical pulses according to the electric stimulation parameters during a treatment session. A method for nerve stimulation includes receiving, by a pulse generator, electric stimulation parameters, and producing, by the pulse generator, electrical pulses according to electric stimulation parameters during a treatment session. The electric stimulation parameters include at least one user-set parameter, which includes a current amplitude that is responsive to the user adjustment of the user control, and at least one physician-set parameter, which includes an upper bound and a lower bound for the current amplitude.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: July 10, 2018
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC.
    Inventors: Ian A. Cook, Christopher M. DeGiorgio, Leon Ekchian, Patrick Miller, Colin Kealey
  • Publication number: 20180110637
    Abstract: A thin-film covered stent device may include a thin-film mesh and a stent backbone covered by the thin-film mesh, thereby forming a dual-layer stent structure. The thin-film covered stent device may have smaller pores and a high pore density compared to conventional stents. For example, the thin-film covered stent device may have a slit length of between 50 and 250 micrometers and a pore density of between 134 and 227 pores per mm2. The thin-film covered stent device facilitates rapid healing of tissue defects such as those encountered during the endovascular treatment of an aneurysm.
    Type: Application
    Filed: December 20, 2017
    Publication date: April 26, 2018
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta
  • Publication number: 20180001077
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Application
    Filed: July 14, 2017
    Publication date: January 4, 2018
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Ian A. Cook, Christopher M. DeGiorgio
  • Publication number: 20170348521
    Abstract: The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.
    Type: Application
    Filed: June 15, 2017
    Publication date: December 7, 2017
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NEUROSIGMA, INC., UNITED STATES GOVERNMENT DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Ian A. Cook, Christopher M. DeGiorgio, Leon Ekchian, Patrick Miller, Antonio De Salles
  • Publication number: 20170265870
    Abstract: Thin-film mesh for medical devices, including stent and scaffold devices, and related methods are provided. Micropatterned thin-film mesh, such as thin-film Nitinol (TFN) mesh, may be fabricated via sputter deposition on a micropatterned wafer. The thin-film mesh may include slits to be expanded into pores, and the expanded thin-film mesh used as a cover for a stent device. The stent device may include two stent modules that may be implanted at a bifurcated aneurysm such that one module passes through a medial surface of the other module. The thin-film mesh may include pores with complex, fractal, or fractal-like shapes. The thin-film mesh may be used as a scaffold for a scaffold device. The thin-film scaffold may be placed in a solution including structural protein such as fibrin, seeded with cells, and placed in the body to replace or repair tissue.
    Type: Application
    Filed: June 6, 2017
    Publication date: September 21, 2017
    Inventors: Colin Kealey, Ian A. Cook, Vikas Gupta