Patents by Inventor Ian A. Harding
Ian A. Harding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240271815Abstract: A method is provided for determining whether a future time period for performing a future process run is satisfactory. The process run employs process equipment disposed within an interior space. In a first step a relationship is obtained between an environmental condition within the interior space and an environmental condition exterior to the interior space. In a second step a future value representative of the environmental condition exterior to the interior space during the future time period is obtained. In a third step a predicted value representative of the environmental condition within the interior space during the future time period is determined by comparing the future value obtained in step (b) to the relationship obtained in step (a). Next the predicted value determined in step (c) is compared to a reference. It is then determined from the comparison whether the future time period for performing the future process run is satisfactory.Type: ApplicationFiled: June 10, 2022Publication date: August 15, 2024Applicant: Elemental Machines, Inc.Inventors: Casey Peters, Sridhar Iyengar, Ian Harding
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Publication number: 20240108697Abstract: Liquid or gel antimicrobial compositions are described. The compositions comprise enzyme that is able to convert a substrate to release hydrogen peroxide; and substrate for the enzyme. The compositions do not comprise sufficient free water to allow the enzyme to convert the substrate, or have a water activity (aw) of 0.7 or less. The compositions may comprise polymer, and there may be greater than 50%, by weight, of the polymer and/or less than 20%, by weight, of sugar in the composition. The compositions may comprise non-aqueous solvent, no honey and 5% or less, by weight, of the substrate in the composition. There may be greater than 50%, by weight, of the non-aqueous solvent and/or there is less than 20%, by weight, of sugar in the composition.Type: ApplicationFiled: March 16, 2021Publication date: April 4, 2024Inventors: Stewart GREEN, Mark BROUGHTON, Wendy RICHINGS-BARROW, Ian HARDING
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Patent number: 11905547Abstract: A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively-charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.Type: GrantFiled: August 27, 2020Date of Patent: February 20, 2024Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Mary Y. Lee, Sandie Tan
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Publication number: 20230419225Abstract: A method for determining whether a given run of a process having a defined protocol is on a trajectory for successful completion is provided. The method includes the step of initiating a run of the defined protocol of the process. During the initiated run, obtaining information reflecting variables that may affect the quality of the process. A preferred trajectory model for achieving a successful implementation of a process is also obtained. The information reflecting the variables that affect the quality of the process are compared with the preferred trajectory model. This comparison allows a determination of offset of the value of the determined variables to the value of the same variables of the preferred trajectory model. The magnitude or amount of offset is indicative of the whether the run initiated in step is on a path or trajectory for success.Type: ApplicationFiled: August 29, 2023Publication date: December 28, 2023Applicant: Elemental Machines, Inc.Inventors: Sridhar Iyengar, Ian Harding
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Publication number: 20230368635Abstract: Determining, generating, and issuing a contextual alert message to a user regarding an alert condition of a process system is provided. Described is determining variable data from a sensor associated with a process system, transmitting a first set of variable data from the sensor to a server and using the server to develop an alert classification model using the first set of variable data, where the alert classification model contains contextual information about an alert condition of the process system, transmitting a second set of data from the sensor to the server and using the server to compare the second set of data to a threshold value to determine if the process system is in an alert condition or approaching an alert condition.Type: ApplicationFiled: September 20, 2021Publication date: November 16, 2023Applicant: Elemental Machines, Inc.Inventors: Ian Harding, Sridhar Iyengar, Casey Peters
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Patent number: 11790299Abstract: A method for determining whether a given run of a process having a defined protocol is on a trajectory for successful completion is provided. The method includes the step of initiating a run of the defined protocol of the process. During the initiated run, obtaining information reflecting variables that may affect the quality of the process. A preferred trajectory model for achieving a successful implementation of a process is also obtained. The information reflecting the variables that affect the quality of the process are compared with the preferred trajectory model. This comparison allows a determination of offset of the value of the determined variables to the value of the same variables of the preferred trajectory model. The magnitude or amount of offset is indicative of the whether the run initiated in step is on a path or trajectory for success.Type: GrantFiled: October 1, 2019Date of Patent: October 17, 2023Assignee: Elemental Machines, Inc.Inventors: Sridhar Iyengar, Ian Harding
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Patent number: 11719687Abstract: A method for obtaining information encoded on an electrochemical test strip is provided. The test strip has two electrodes disposed within a sample space and the information is encoded on the test strip prior to introduction of liquid sample. The method includes the step of introducing sample to the sample space so that the sample is in contact with the two electrodes within the sample space. In another step a value is determined that is representative of the double layer capacitance of the test strip and/or the equivalent capacitance of the test strip. The determined value is then translated into information reflecting a characteristic of the test strip prior to introduction of sample.Type: GrantFiled: December 17, 2018Date of Patent: August 8, 2023Assignee: AgaMatrix, Inc.Inventors: Sridhar Iyengar, Ian Harding, Richard Williams, Kevin Cai
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Publication number: 20230204646Abstract: An electromagnetic apparatus (EMA) for measuring electromagnetic properties of an electrical conductor such as a power cord is provided. Methods of using the EMA are also provided. The EMA includes a plurality of electromagnetic sensors (EMSs) disposed in an array along a length and a width of the EMA. The EMA further includes circuitry such as a microprocessor, communication circuitry, and power circuitry. The circuitry is in electrical communication with the EMSs.Type: ApplicationFiled: February 17, 2021Publication date: June 29, 2023Applicant: Elemental Machines, Inc.Inventors: Alex Nichols, Casey Peters, Lauren Lisle, John Sakalowsky, Ian Harding, Sridhar Iyengar
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Patent number: 11408849Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: GrantFiled: April 6, 2020Date of Patent: August 9, 2022Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
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Publication number: 20220175829Abstract: Liquid compositions are described which have enzyme that is able to convert a substrate to release hydrogen peroxide; substrate for the enzyme; and polymer. The substrate is less than 10% by weight of the composition and the composition does not comprise sufficient free water to allow the enzyme to convert the substrate, or has a water activity of 0.7 or less.Type: ApplicationFiled: March 27, 2020Publication date: June 9, 2022Inventors: Stewart Green, Mark Broughton, Wendy Richings-Barrow, Ian Harding
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Patent number: 11346803Abstract: A test strip and analytical apparatus have pin connections permitting the definition of geographic regions or of particular customers. A test strip made for use in a particular region or for a particular customer will have pin connections matching features of the apparatus made for use in that region or by that customer. Insertion of the strip into the apparatus does not merely turn on the apparatus, but provides the regional or customer coding. Analog switches within the apparatus allow coding of a larger number of distinct regions or customers than would otherwise be possible, all without degrading the quality of the measurements made of the fluid being tested. Conductive paths in the strips permit testing the strips during manufacture so as to detect quality lapses regarding the printing or deposition of the paths.Type: GrantFiled: December 4, 2017Date of Patent: May 31, 2022Assignee: AgaMatrix, Inc.Inventors: Steven Diamond, Martin Forest, Baoguo Wei, Ian Harding, Sridhar Iyengar
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Publication number: 20220154120Abstract: Devices and systems for cell culture analysis are provided. A device for cell culture analysis includes a first component comprising a receptacle configured to receive a cell culture insert having an apical surface and a basal surface and a second component. The device further includes an inlet port disposed at at least one of the first and second components and an outlet port disposed at at least one of the first and second components. The first component and second component are releasably couplable and configured to define a flow path from the inlet port to the outlet port when in a coupled state. The flow path is at least partially defined by a surface of the second component, and the first component is configured to expose the basal surface of the cell culture insert to the flow path.Type: ApplicationFiled: November 12, 2021Publication date: May 19, 2022Inventors: Eno Essien Ebong, Ian Harding, Ira M. Herman, Abigail N. Koppes, Alex Caraballo, Nicholas O'Hare, Mark Vigliotti
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Patent number: 11175256Abstract: An electrochemical test device is provided having a base layer with a first electrode thereon and a top layer with a second electrode thereon. The two electrodes are separated by a spacer layer having an opening therein, such that a sample-receiving space is defined with one electrode on the top surface, the other electrodes on the bottom surface and side walls formed from edges of the opening in the spacer. Reagents for performing the electrochemical reaction are deposited on one of the electrodes and on the side walls of the sample-receiving space.Type: GrantFiled: August 27, 2013Date of Patent: November 16, 2021Assignee: AgaMatrix, Inc.Inventor: Ian Harding
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Publication number: 20210303628Abstract: An empirical data management system (EDMS) includes an application server, an environmental sensor unit, a process instrument, a data storage system, and a correlation module. If a correlation exists between two or more of process data, environmental data, and specified environmental operating ranges of the process instrument, a user is prompted with a specific message such as a recommendation, warning and/or query.Type: ApplicationFiled: March 31, 2020Publication date: September 30, 2021Applicant: Elemental Machines, Inc.Inventors: Ian Harding, Sridhar Iyengar
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Patent number: 10983083Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.Type: GrantFiled: June 15, 2017Date of Patent: April 20, 2021Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
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Publication number: 20200392556Abstract: A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively-charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.Type: ApplicationFiled: August 27, 2020Publication date: December 17, 2020Applicant: AgaMatrix, Inc.Inventors: Ian Harding, Mary Y. Lee, Sandie Tan
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Publication number: 20200333282Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: ApplicationFiled: April 6, 2020Publication date: October 22, 2020Applicant: AgaMatrix, Inc.Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
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Patent number: 10760111Abstract: A dry reagent composition that includes an active redox enzyme that oxidizes an analyte as a specific substrate to produce an inactive reduced form of the enzyme; and a salt of ferricyanide provides improved performance in electrochemical test strips such as those used for detection of glucose. The salt of ferricyanide consists of ferricyanide and positively-charged counter ions, and the positively charged counter ions are selected such that the salt of ferricyanide is soluble in water, and such that the salt of ferricyanide or the crystalline phase of the salt of ferricyanide has a solubility in water and/or a lower E0eff at a concentration of 100 mM than potassium ferricyanide. For example, the salt of ferricyanide may be tetramethylammonium ferricyanide.Type: GrantFiled: July 25, 2012Date of Patent: September 1, 2020Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Mary Y. Lee, Sandie Tan
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Patent number: 10641725Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.Type: GrantFiled: November 29, 2017Date of Patent: May 5, 2020Assignee: AgaMatrix, Inc.Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
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Publication number: 20200103259Abstract: An empirical data management system (EDMS), such as an electronic laboratory notebook (ELN) system, includes an application server running an EDMS server application, a data storage system containing data in communication with the application server, and an environmental sensor unit in communication with the application server. The data comprises environmental data received from the environmental sensor unit.Type: ApplicationFiled: October 1, 2019Publication date: April 2, 2020Applicant: Elemental Machines, Inc.Inventors: Ian Harding, Sridhar Iyengar