Patents by Inventor Ian A. Nicholls

Ian A. Nicholls has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for detecting pharmaceuticals in a sample
    Patent number: 8841633
    Abstract: A method and apparatus for measuring a vitamin K antagonizing anticoagulant present in a sample (116), arranged to: irradiate (304) the sample (116) with light from a light source (114) for exciting the anticoagulant through its absorption of the light, the excitation of the sample (116) resulting in a fluorescent emission from the sample (116); measure (306) the fluorescent emission from the sample (116); determine (308) a fluorescence lifetime (T1) of the fluorescent emission of the sample (116); determine (310) an intensity (A1) of the fluorescent emission at the fluorescence lifetime (T1); and determine (312) a amount (c) of the anticoagulant, as a function of the intensity (A1) of the fluorescent emission at the fluorescence lifetime (T1).
    Type: Grant
    Filed: March 25, 2010
    Date of Patent: September 23, 2014
    Inventors: Ian A Nicholls, Bjorn C.G. Karlsson, Annika M Rosengren, Per Ola Andersson
  • METHOD AND APPARATUS FOR DETECTING PHARMACEUTICALS IN A SAMPLE
    Publication number: 20120032095
    Abstract: A method and apparatus for measuring a vitamin K antagonizing anticoagulant present in a sample (116), arranged to: irradiate (304) the sample (116) with light from a light source (114) for exciting the anticoagulant through its absorption of the light, the excitation of the sample (116) resulting in a fluorescent emission from the sample (116); measure (306) the fluorescent emission from the sample (116); determine (308) a fluorescence lifetime (?1) of the fluorescent emission of the sample (116); determine (310) an intensity (A1) of the fluorescent emission at the fluorescence lifetime (?1); and determine (312) a amount (c) of the anticoagulant, as a function of the intensity (A1) of the fluorescent emission at the fluorescence lifetime (?1).
    Type: Application
    Filed: March 25, 2010
    Publication date: February 9, 2012
    Inventors: Ian A. Nicholls, Bjorn C.G. Karlsson, Annika M. Rosengren, Per Ola Andersson
  • Use of molecularly imprinted polymers for stereo- and/or regioselective synthesis
    Publication number: 20050027102
    Abstract: Molecularly imprinted polymers can be utilized in stereo- and regio-selective synthesis. These systems can be utilized, e.g. for peptide synthesis, by selectively coordinating reactants at a predetermined preformed cavity. Further, such polymers may be used for the selective removal of one enantiomeric species from solution, allowing reaction to be directed to another species in bulk solution leading to stereoselective and/or regio-selective synthesis in the cavity of for instance peptides. Additionally, when utilized as regioselectively interacting protectioning matrices, these polymers can direct reaction to an alternate centre of a reacting substrate.
    Type: Application
    Filed: August 24, 2004
    Publication date: February 3, 2005
    Inventors: Klaus Mosbach, Ian Nicholls, Olof Ramstrom