Patents by Inventor Ian Andrew Wilson

Ian Andrew Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ANTIBODY SEQUENCES FOR DIAGNOSTICS AND THERAPEUTICS
    Publication number: 20240390531
    Abstract: Aspects of the present disclosure relate generally to novel antigen binding sequences and uses thereof. More specifically, certain features of the present disclosure concern antibodies, minibodies, and cys-diabodies for use in targeting the protein FAP. The antigen binding sequences herein may be used as part of treatment to confer health benefits to subjects in need thereof. The antigen binding sequences can also be used for detection, targeting, and imaging purposes.
    Type: Application
    Filed: July 8, 2022
    Publication date: November 28, 2024
    Inventors: Alessandro MASCIONI, Fang JIA, Leticia Maria DE SOUZA CORDEIRO, Kelley C. ATKINSON, Patrick JOYCE, Argin AIVAZIAN, Zheng LIU, Ian Andrew WILSON
  • METHODS OF IMAGING USING MULTIPLE IMAGING AGENTS
    Publication number: 20230211024
    Abstract: Methods of non-invasively imaging a subject using two or more antigen-binding constructs that selectively bind to immune cell markers are described.
    Type: Application
    Filed: December 3, 2020
    Publication date: July 6, 2023
    Inventors: Alessandro Mascioni, Ian Andrew Wilson, Ivan Plavec, William Huy Le
  • CD8 IMAGING CONSTRUCTS AND METHODS OF USE THEREOF
    Publication number: 20220001043
    Abstract: Antigen binding constructs that bind to CD8, as well as formulations and methods of using them, are described herein.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 6, 2022
    Inventors: Ian Andrew Wilson, Deepak Behera, William Huy Le
  • Anti-met therapy for previously diagnosed cancer patients
    Patent number: 9956303
    Abstract: The present invention relates to methods useful in the selection of cancer patients suitable for treatment with therapies directed at c-Met. The method employs imaging agents which comprise 18F-radiolabelled c-Met binding peptides suitable for positron emission tomography (PET) imaging in vivo. Also disclosed are methods of treatment, methods of monitoring therapy directed atc-Met and the use of the imaging agents and peptides in the methods of the invention.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: May 1, 2018
    Assignee: GE HEALTHCARE LIMITED
    Inventors: Grethe Tang Dalsgaard, Ian Andrew Wilson
  • METHOD FOR PATIENT SELECTION
    Publication number: 20140335022
    Abstract: The present invention relates to methods useful in the selection of cancer patients suitable for treatment with therapies directed at c-Met. The method employs imaging agents which comprise 18F-radiolabelled c-Met binding peptides suitable for positron emission tomography (PET) imaging in vivo. Also disclosed are methods of treatment, methods of monitoring therapy directed atc-Met and the use of the imaging agents and peptides in the methods of the invention.
    Type: Application
    Filed: December 19, 2012
    Publication date: November 13, 2014
    Inventors: Grethe Tang Dalsgaard, Ian Andrew Wilson
  • Labelled glutamine and lysine analogues
    Patent number: 7049289
    Abstract: Synthetic analogues of lysine and glutamine are provided which function as substrates for the fibrin-stabilising enzyme Factor XIIIa even when labelled with a detectable moiety. The use of suitable protecting groups provides compounds which possess reduced susceptibility to in vivo metabolism especially by peptidases, and are hence useful agents for the diagnosis of thrombosis, embolism, atherosclerosis, inflammation or cancer.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: May 23, 2006
    Assignee: Amersham PLC
    Inventors: Anthony Eamon Storey, Marivi Mendizabal, Susan Champion, Alex Gibson, Benedicte Guilbert, Ian Andrew Wilson, Peter Knox
  • Labelled factor XIIIa substrates
    Patent number: 6897209
    Abstract: A complex of a radiometal or paramagnetic metal ion with a metal chelating agent such as a diaminedioxime has attached thereto a substituent of formula (Y)m-A-NHR)k can function as a substrate for the fibrin-stabilizing Factor XIIIa. The complex is useful for the diagnosis or therapy of thrombosis, embolism, atherosclerosis, inflammation or cancer.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: May 24, 2005
    Assignee: GE Healthcare Limited
    Inventors: Alan Michael Forster, Peter Knox, Marivi Mendizabal, Timothy Charles Richardson, Anthony Eamon Storey, Ian Andrew Wilson, Susan Champion, Alex Gibson, Benedicte Guilbert
  • Labelled factor XIIIa substrates
    Publication number: 20040076580
    Abstract: A complex of a radiometal or paramagnetic metal ion with a metal chelating agent such as a diaminedioxime has attached thereto a substituent of formula (Y)m—A—NHR)k can function as a substrate for the fibrin-stabilizing Factor XIIIa. The complex is useful for the diagnosis or therapy of thrombosis, embolism, atherosclerosis, inflammation or cancer.
    Type: Application
    Filed: August 22, 2003
    Publication date: April 22, 2004
    Applicant: AMERSHAM PLC
    Inventors: Alan Michael Forster, Peter Knox, Marivi Mendizabal, Timothy Charles Richardson, Anthony Eamon Storey, Ian Andrew Wilson, Susan Champion, Alex Gibson, Benedicte Guilbert
  • Labelled factor XIIIa substrates
    Patent number: 6653299
    Abstract: A complex of a radiometal or paramagnetic metal ion with a metal chelating agent such as a diaminedioxime has attached thereto a substituent of formula —(Y)m—A—NHR, can function as a substrate for the fibrin-stabilizing Factor XIIIa. The complex is useful for the diagnosis or therapy of thrombosis, embolism, atherosclerosis, inflammation or cancer.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: November 25, 2003
    Assignee: Nycomed Amersham PLC
    Inventors: Alan Michael Forster, Peter Knox, Marivi Mendizabal, Timothy Charles Richardson, Anthony Eamon Storey, Ian Andrew Wilson, Susan Champion, Alex Gibson, Benedicte Guilbert