Patents by Inventor Ian Ashworth

Ian Ashworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for asymmetric synthesis of substituted 1,4 -dihydropyridines
    Patent number: 7074931
    Abstract: A process is described for reacting a vinylogous amide with an ?,?-unsaturated ketone in the presence of a silicon compound to form an 1,5-diketone which is converted to a 1,4-dihydropyridine. Asymmetric substituted 1,4-dihydropyridines are synthesized by the process by preparing an asymmetric vinylogous amide by reacting a 1,3-cyclohexanedione with a substantially homo-chiral phenylethylamine. Reaction of the asymmetric vinylogous amide with an ?,?-unsaturated ketone in the presence of a silicon compound forms an asymmetric 1,5-diketone. The 1,5-diketone is converted to an asymmetric substituted 1,4-dihydropyridine.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: July 11, 2006
    Assignee: Astrazeneca AB
    Inventors: Ian Patel, Ian Ashworth, Daniel Levin
  • Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof
    Publication number: 20050182269
    Abstract: The present invention is related to a process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof of formula (1), the intermediate 1-halo-3-cyano naphthalene and some analogues thereof used in this process and a process for the preparation of said intermediate.
    Type: Application
    Filed: June 18, 2003
    Publication date: August 18, 2005
    Inventors: Ian Ashworth, Martin Bowden, Bruce Dembofsky, Daniel Levin
  • Process for asymmetric synthesis of substituted 1,4 -dihydropyridines
    Publication number: 20040039207
    Abstract: A process is described for reacting a vinylogous amide with an &agr;,&bgr;-unsaturated ketone in the presence of a silicon compound to form an 1,5-diketone which is converted to a 1,4-dihydropyridine. Asymmetric substituted 1,4-dihydropyridines are synthesized by the process by preparing an asymmetric vinylogous amide by reacting a 1,3-cyclohexanedione with a substantially homo-chiral phenylethylamine. Reaction of the asymmetric vinylogous amide with an &agr;,&bgr;-unsaturated ketone in the presence of a silicon compound forms an asymmetric 1,5-diketone. The 1,5-diketone is converted to an asymmetric substituted 1,4-dihydropyridine.
    Type: Application
    Filed: January 21, 2003
    Publication date: February 26, 2004
    Inventors: Ian Patel, Ian Ashworth, Daniel Levin
  • Body holster
    Patent number: D464194
    Type: Grant
    Filed: December 27, 2001
    Date of Patent: October 15, 2002
    Assignee: Bodyguard International Limited
    Inventor: Ian Ashworth